Phenylhydrazines
Medchemexpress LLC Valacyclovir hydrochloride | 124832-27-5 | 99.9% | 360.80 | 100 MG
Valacyclovir hydrochloride is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. It inhibits HSV-1 W (50=2.9 μg/ml) and is a proagent of Aciclovir.
- IC50 and target: HSV-1, 2.9 μg/mL (IC50).
- In vitro: Uptake is concentration dependent and saturable, with hPEPT1 dominating intestinal transport.
- In vivo: Effective for treating genital herpes (1 g twice daily) and recurrences. A 1 g daily dose is as effective as 2 g daily and can be administered once a day. Studies in immunosuppressed mice showed reduced erythema, eliminated ear paralysis, ear lesions, and death.
Medchemexpress LLC (R,E)-N-(Cyclopropylmethyl)-N-methyl-3,6-diphenylhex-5-en-3-amine hydrochloride | 99.0% | 355.94 | 1 ML
(+)-Igmesine hydrochloride is a white to off-white solid that has been tested and complies with given specifications. It is suitable for various laboratory applications requiring precise chemical properties.
- Stored at -20°C, protected from light, under nitrogen.
- In solvent, stored at -80°C for 6 months or -20°C for 1 month, protected from light, under nitrogen.
- High purity of 99.0% (HPLC).
Medchemexpress LLC Padoprazanum hydrochloride | 2940882-02-8 | 98.7% | 10 MG
Padoprazanum hydrochloride is the hydrochloride salt of padoprazan, a potassium-competitive acid blocker supplied as a research reagent for inhibition of gastric acid secretion. It is provided in small milligram-scale pack sizes for laboratory use.
- High chemical purity (98.7%).
- Molecular weight 441.90 g/mol.
- Chemical formula C19H21ClFN3O4S.
- Available in small mg pack sizes suitable for assay and in vitro studies.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Hydroxylamine, O-methyl-, hydrochloride (1:1) | 593-56-6 | MFCD00012951 | 98.0% | 83.52 | CH6ClNO | 50g
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor Methoxyamine hydrochloride binds to 3 hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents[1][2]
eMolecules 6971-45-5 | 2-Methoxyphenylhydrazine Hydrochloride | Ambeed | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 5g | 552742604
2-Methoxyphenylhydrazine Hydrochloride | Ambeed | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 5g | 552742604
Medchemexpress LLC Medetomidine (hydrochloride) | 86347-15-1 | 99.8% | 236.74 | 100 MG
Medetomidine hydrochloride is an analytical standard of Medetomidine (hydrochloride), intended for research and analytical applications. This orally active α2-adrenoceptor agonist, with a Ki of 1.08 nM, exhibits sedative and analgesic effects, and can induce peripheral vasoconstriction. It serves as a reference standard for assays and is commonly utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Orally active α2-adrenoceptor agonist (Ki: 1.08 nM)
- Provides sedative and analgesic effects
- Induces peripheral vasoconstriction
- Reference standard for assays
- Suitable for HPLC, GC, and MS research experiments
Medchemexpress LLC Procarbazine hydrochloride | 366-70-1 | 99.7% | 257.76 | 100 MG
Procarbazine hydrochloride is an orally active alkylating agent exhibiting anticancer activity, particularly noted for its use in Hodgkin's disease research. This compound is provided as an off-white to light yellow solid, stable under recommended storage conditions.
- Orally active alkylating agent
- Possesses anticancer activity
- Useful in Hodgkin's disease research
- Stable under recommended storage conditions
- Can induce micronuclei in hematopoietic cells
- Applicable for cell survival studies
Medchemexpress LLC M-peg3-0-benzaldehyde | 153364-63-7 | C14H20O5 | 250 MG
m-PEG3-0-benzaldehyde is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only and is not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs exploit the ubiquitin-proteasome system
- Selectively degrade target proteins
- For research use only
Medchemexpress LLC Ampreloxetine hydrochloride | 1227056-87-2 | 99.5% | 357.80 | C18H19ClF3NO | 10 MG
Ampreloxetine hydrochloride is the hydrochloride salt of ampreloxetine (TD-9855), an orally active, CNS-penetrant inhibitor of norepinephrine and serotonin reuptake. Supplied as a research-grade small-molecule reagent, it is intended for preclinical pharmacology and transporter studies investigating NET and SERT function.
- High reported purity (99.5%) suitable for research assays.
- Provided as a solid for accurate weighing and formulation.
- Suitable for in vitro and in vivo preclinical studies of monoamine transporters.
- Well-characterized molecular properties (C18H19ClF3NO, MW 357.80).
- Available in small milligram package sizes for dose-ranging and screening.
Medchemexpress LLC Cdk4/6-in-15 | 00-00-0 | 99.3% | 442.56 g/mol | C21H27FN8S | 5 MG
CDK4/6-IN-15 is an orally active, selective inhibitor of cyclin-dependent kinases CDK4 and CDK6 used in cellular and biochemical research to probe cell-cycle regulation and anticancer activity. It arrests cells in G1, suppresses Rb phosphorylation, and has demonstrated antiproliferative and pro-apoptotic effects in multiple cell lines.
- selective inhibitor of CDK4 and CDK6 with potent activity
- arrests the cell cycle at G1 and reduces Rb phosphorylation
- demonstrated antiproliferative and pro-apoptotic effects in cell assays
- soluble in DMSO with stock preparation guidance for common concentrations
- stable when protected from light; storage recommendations provided
Aobchem (3-Bromo-2-formyl-5-methylphenyl)boronic acid | 97% | C8H8BBrO3 | 5g
(3-Bromo-2-formyl-5-methylphenyl)boronic acid | 97% | C8H8BBrO3 | 5g
Medchemexpress LLC JBSNF-000028 hydrochloride | C11H14ClN3 | 25 MG
JBSNF-000028 hydrochloride is an orally active small molecule inhibitor of tricyclic nicotinamide N-methyltransferase (NNMT). It demonstrates anti-obesity and anti-diabetic activities in the diet-induced obesity (DIO) model, suitable for research into metabolic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease.
- Orally active small molecule inhibitor of tricyclic nicotinamide N-methyltransferase (NNMT)
- Reduces endogenous MNA levels in U2OS osteosarcoma cells with an EC50 of 2.5 μM
- Exhibits anti-obesity and anti-diabetic activities in diet-induced obesity (DIO) model
- Useful for studying metabolic diseases (obesity, type 2 diabetes, non-alcoholic fatty liver disease)
- IC50 values for NNMT: 33 nM (human), 210 nM (mouse), 190 nM (monkey)
Aobchem Ethyl 2-(3-chloro-5-methylphenyl)-2-oxoacetate | 95% | CAS 1256481-74-9 | C11H11ClO3 | 1g
Ethyl 2-(3-chloro-5-methylphenyl)-2-oxoacetate | 95% | CAS 1256481-74-9 | C11H11ClO3 | 1g
Aobchem (6-Bromo-2-fluoro-3-methylphenyl)(m-tolyl)methanol | 97% | CAS 3002520-50-2 | C15H14BrFO | 1g
(6-Bromo-2-fluoro-3-methylphenyl)(m-tolyl)methanol | 97% | CAS 3002520-50-2 | C15H14BrFO | 1g
Aobchem 2-Chloro-5-fluoro-4-methylphenylboronic acid | ≥97% | CAS 1612184-35-6 | C7H7BClFO2 | 250mg
2-Chloro-5-fluoro-4-methylphenylboronic acid | ≥97% | CAS 1612184-35-6 | C7H7BClFO2 | 250mg