Phthalic acid and derivatives
Medchemexpress LLC Fosbretabulin disodium | 168555-66-6 | MFCD00943911 | 99.9% | 440.29 g/mol | C18H19Na2O8P | 10 MG
Fosbretabulin disodium is a water-soluble phosphate prodrug of combretastatin A4 that destabilizes microtubules and acts as a vascular-disrupting agent used in preclinical oncology research. It selectively targets tumor endothelial cells, reduces tumor blood flow, and induces central tumor necrosis; supplied as a disodium phosphate salt for laboratory use.
- Microtubule-destabilizing vascular-disruptor mechanism.
- Water-soluble disodium phosphate prodrug form.
- High purity (≈99.9%).
- Molecular weight 440.29 g/mol; formula C18H19Na2O8P.
- Available in small research quantities (1-100 mg) and 10 mM aqueous solutions.
- Intended for preclinical and in vitro research applications.
Medchemexpress LLC Calcium disodium edetate hydrate | 23411-34-9 | MFCD00148919 | 98.0% | 374.27 g·mol⁻¹ | C10H12CaN2O8.xH2O.2Na | 10 G
Calcium disodium edetate hydrate is a research-grade chelating reagent used to bind divalent metal ions in biochemical and toxicology studies. Supplied as a solid, it is commonly used for metal-chelation experiments, sample stabilization, and preparation of buffer solutions in life science research.
- High purity (98.0%) suitable for research applications.
- Solid form for easy weighing and accurate dosing.
- Effective chelation of divalent metal ions such as lead and cadmium.
- Compatible with aqueous buffers and typical laboratory solvents.
- Store sealed, away from moisture and light; in solution: -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Methotrexate disodium 7413-34-5 200mg
Methotrexate disodium (CAS 7413-34-5) is a small-molecule inhibitor targeting dihydrofolate reductase (DHFR) It is designed to inhibit DHFR activity thereby disrupting the enzymatic reduction of dihydrofolate to tetrahydrofolate and impairing DNA and RNA biosynthesis Methotrexate disodium exerts its biological activity primarily through DHFR inhibition In in vitro studies methotrexate disodium demonstrates inhibitory activity with an IC50 value in the nanomolar range (approximately 5 to 50 nM depending on assay conditions and cell models) Based on these pharmacological properties methotrexate disodium holds research potential in autoimmune disorders such as rheumatoid arthritis and psoriasis as well as in antineoplastic studies involving acute lymphoblastic leukemia
Medchemexpress LLC Cyclic GMP (Standard) | 7665-99-8 | 99.5% | 345.21 | 50 MG
Cyclic GMP (Standard) | 7665-99-8 | 99.5% | 345.21 | 50 MG
Medchemexpress LLC Cyclic adenosine monophosphate | 60-92-4 | 99.9% | 100 MG
Cyclic AMP (Standard) is the analytical standard of Cyclic AMP, an adenosine triphosphate derivative and an intracellular signaling molecule. It is an important second messenger in many biological processes, directing cellular responses to extracellular signals.
- Used as a reference standard in assays
- Utilized in qualitative, quantitative, and methodological research experiments
- Suitable for applications involving HPLC, GC, and MS
Medchemexpress LLC Adenosine, cyclic 3',5'-(hydrogen phosphate) | 60-92-4 | 99.9% | 1G
Cyclic AMP (Cyclic adenosine monophosphate), an adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. It acts as an important second messenger in many biological processes.
- Intracellular signaling molecule for cellular responses to extracellular signals.
- Modulates mediator generation.
- Suppresses expression of pro-inflammatory cytokines like TNF-α and IL-12.
- Enhances production of anti-inflammatory cytokine IL-10.
- Functions as a microbial and human endogenous metabolite.
Medchemexpress LLC 8-(4-chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt | 93882-12-3 | 99.9% | 493.79 g/mol | C16H14ClN5NaO6PS | 5 MG
8-CPT-Cyclic AMP sodium is a membrane-permeable cyclic AMP analog that selectively activates cAMP-dependent protein kinase (PKA) and inhibits certain phosphodiesterases. Supplied as the monosodium salt in solid form, it is used to elevate intracellular cAMP levels and to probe cAMP/PKA signaling pathways in biochemical and cell-based assays.
- Selective activator of cAMP-dependent protein kinase.
- Membrane-permeable cyclic AMP analog (monosodium salt).
- High purity (~99.9%) for reproducible experimental results.
- Soluble in DMSO and water with sonication and warming as needed.
- Solid storage at -20°C; in solution store at -80°C for long-term stability.
- Available in small-scale solid quantities and in ready-to-use solution format.
