Phthalic acid and derivatives
Sodium Terephthalate, MP Biomedicals
CAS: 10028-70-3 Molecular Formula: C8H4Na2O4 Molecular Weight (g/mol): 210.096 InChI Key: VIQSRHWJEKERKR-UHFFFAOYSA-L Synonym: disodium terephthalate,terephthalic acid disodium salt,terephthalic acid, disodium salt,sodium terephthalate,unii-gi30zoc0oo,gi30zoc0oo,disodiumterephthalate,acmc-1bvw0,disodium terephthalate 5g,1,4-benzenedicarboxylicacid, sodium salt 1:? PubChem CID: 82305 IUPAC Name: disodium;terephthalate SMILES: C1=CC(=CC=C1C(=O)[O-])C(=O)[O-].[Na+].[Na+]
Sodium Dimethyl 5-Sulfoisophthalate 98.0+%, TCI America™
CAS: 3965-55-7 Molecular Formula: C10H9NaO7S Molecular Weight (g/mol): 296.225 MDL Number: MFCD00007493 InChI Key: LLHSEQCZSNZLRI-UHFFFAOYSA-M Synonym: sodium 3,5-bis methoxycarbonyl benzenesulfonate,sodium dimethyl 5-sulphonatoisophthalate,dimethyl 5-sulfoisophthalate sodium salt,unii-7l3g5x9vdu,sodium 1,3-dimethyl 5-sulfoisophthalate,7l3g5x9vdu,5-sulfoisophthalic acid, dimethyl ester, sodium salt,sodium dimethyl 5-sulfoisophthalate,1,3-benzenedicarboxylic acid, 5-sulfo-, 1,3-dimethyl ester, sodium salt,3,5-bis-methylkarboxy-benzensulfonan sodny czech PubChem CID: 23675796 IUPAC Name: sodium;3,5-bis(methoxycarbonyl)benzenesulfonate SMILES: COC(=O)C1=CC(=CC(=C1)S(=O)(=O)[O-])C(=O)OC.[Na+]
Disodium terephthalate, 99+%
CAS: 10028-70-3 Molecular Formula: C8H4Na2O4 Molecular Weight (g/mol): 210.096 MDL Number: MFCD00013137 InChI Key: VIQSRHWJEKERKR-UHFFFAOYSA-L Synonym: disodium terephthalate,terephthalic acid disodium salt,terephthalic acid, disodium salt,sodium terephthalate,unii-gi30zoc0oo,gi30zoc0oo,disodiumterephthalate,acmc-1bvw0,disodium terephthalate 5g,1,4-benzenedicarboxylicacid, sodium salt 1:? PubChem CID: 82305 IUPAC Name: disodium;terephthalate SMILES: C1=CC(=CC=C1C(=O)[O-])C(=O)[O-].[Na+].[Na+]
Disodium Terephthalate 99.0+%, TCI America™
CAS: 10028-70-3 Molecular Formula: C8H4Na2O4 Molecular Weight (g/mol): 210.096 MDL Number: MFCD00013137 InChI Key: VIQSRHWJEKERKR-UHFFFAOYSA-L Synonym: disodium terephthalate,terephthalic acid disodium salt,terephthalic acid, disodium salt,sodium terephthalate,unii-gi30zoc0oo,gi30zoc0oo,disodiumterephthalate,acmc-1bvw0,disodium terephthalate 5g,1,4-benzenedicarboxylicacid, sodium salt 1:? PubChem CID: 82305 IUPAC Name: disodium;terephthalate SMILES: C1=CC(=CC=C1C(=O)[O-])C(=O)[O-].[Na+].[Na+]
Medchemexpress LLC Cyclic AMP sodium | 37839-81-9 | 99.97% | 250 MG
Cyclic AMP (Cyclic adenosine monophosphate) sodium, an adenosine triphosphate derivative, is an intracellular signaling molecule that directs cellular responses to extracellular signals. It acts as an important second messenger in many biological processes. It also modulates mediator generation, suppressing the expression of pro-inflammatory cytokines and enhancing the production of anti-inflammatory cytokine.
- Acts as an important second messenger
- Modulates mediator generation
- Suppresses pro-inflammatory cytokines like TNF-α and IL-12
- Enhances anti-inflammatory cytokine IL-10 production
Medchemexpress LLC Cyclic adenosine monophosphate sodium | 37839-81-9 | 100.0% | 100 MG
Cyclic AMP (Cyclic adenosine monophosphate) sodium, an adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. It is an important second messenger in many biological processes. It modulates mediator generation, suppresses the expression of pro-inflammatory cytokines, including TNF-α and IL-12, and enhances the production of the anti-inflammatory cytokine IL-10.
- Acts as an intracellular signaling molecule.
- Directs cellular responses to extracellular signals.
- Is an important second messenger in many biological processes.
- Modulates mediator generation.
- Suppresses pro-inflammatory cytokines.
- Enhances anti-inflammatory cytokine production.
Medchemexpress LLC Cyclic GMP sodium | 40732-48-7 | 99.9% | 367.19 | 10 MG
Cyclic GMP sodium | 40732-48-7 | 99.9% | 367.19 | 10 MG
Medchemexpress LLC Cyclic GMP sodium | 40732-48-7 | 99.9% | 367.19 | 25 MG
Cyclic GMP (cGMP) sodium is an important second messenger and a major intracellular mediator of extracellular signals like nitric oxide (NO) and natriuretic peptides (NPs). Its effects are mediated through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and phosphodiesterases (PDEs). It can inhibit both platelet adhesion and aggregation, and its conjugate, cGAMP, can enhance antiviral immune responses.
- Important second messenger.
- Major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs).
- Mediates effects through cGMP-dependent protein kinases, cGMP-gated cation channels, and PDEs.
- Inhibits platelet adhesion and aggregation.
- Can enhance antiviral immune responses through its conjugate.
- Activates cGMP-stimulated phosphodiesterases synergistically with Isoprenaline.
Medchemexpress LLC Cyclic AMP (sodium) | 37839-81-9 | 100.0% | 10 MM, 1 ML
Cyclic AMP (Cyclic adenosine monophosphate) sodium, an adenosine triphosphate derivative, is an intracellular signaling molecule that directs cellular responses to extracellular signals. It serves as an important second messenger in many biological processes.
- Intracellular signaling molecule
- Directs cellular responses to extracellular signals
- Important second messenger in many biological processes
- Modulates mediator generation
- Suppresses the expression of pro-inflammatory cytokines (TNF-α and IL-12)
- Enhances the production of the anti-inflammatory cytokine IL-10
Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 25 MG
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also identified as a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. Additionally, 8-CPT-Cyclic AMP sodium inhibits PDE III and PDE IV with IC50Epac and functions as a potent Epac activator.
- Selective activator of cyclic AMP-dependent protein kinase (PKA).
- Potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM.
- Inhibits PDE III and PDE IV.
- Potent Epac activator.
- Delays TNF-/CHX-induced and α-Fas-induced apoptosis in neutrophils.
Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 50 MG
8-CPT-Cyclic AMP sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA) and a potent Epac activator. It also acts as an inhibitor for specific phosphodiesterases.
- Selective activator of cyclic AMP-dependent protein kinase (PKA).
- Potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM.
- Inhibits PDE III and PDE IV.
- Potent Epac activator.
Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 10 MG
8-CPT-Cyclic AMP sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. Additionally, 8-CPT-Cyclic AMP sodium inhibits PDE III and PDE IV with IC50 values of 5.5 μM and 6.6 μM, respectively, and is a potent Epac activator. It has been shown to delay TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
- Selective activator of cyclic AMP-dependent protein kinase (PKA).
- Potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM.
- Inhibits PDE III and PDE IV with IC50 values of 5.5 μM and 6.6 μM.
- Potent Epac activator.
- Delays TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 100 MG
8-CPT-Cyclic AMP sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM, and it inhibits PDE III and PDE IV with IC50Epac, functioning as a potent Epac activator.
- Delays TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
- More effective against apoptosis induced by TNF-α/CHX than by α-Fas.
![Medchemexpress LLC Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-(hydrogen phosphate), sodium salt | 93882-12-3 | 99.9% | 493.79 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000438753-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-(hydrogen phosphate), sodium salt | 93882-12-3 | 99.9% | 493.79 | 1 ML
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM, and inhibits PDE III and PDE IV with IC50Epac. 8-CPT-Cyclic AMP sodium is also a potent Epac activator. It has been shown to delay TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils at a concentration of 0.7 mM, being more efficient against apoptosis induced by TNF-α/CHX.
- Selective activator of cyclic AMP-dependent protein kinase (PKA).
- Potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA).
- Inhibits PDE III and PDE IV.
- Potent Epac activator.
- Can delay TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
![Medchemexpress LLC Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate), sodium salt (1:2) | 168555-66-6 | 99.55% | 440.29 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386671-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate), sodium salt (1:2) | 168555-66-6 | 99.55% | 440.29 | 1 ML
Fosbretabulin disodium is a tubulin destabilizing agent and a Combretastatin A4 proagent. It selectively targets endothelial cells, leading to the regression of nascent tumor neovessels, reduced tumor blood flow, and central tumor necrosis. This compound has demonstrated inhibitory effects on the growth of various cancer cell lines and increases mean arterial blood pressure while decreasing tumor blood flow in vivo.
- Tubulin destabilizing agent
- Combretastatin A4 proagent
- Selectively targets endothelial cells
- Induces regression of nascent tumor neovessels
- Reduces tumor blood flow
- Causes central tumor necrosis
- Inhibits growth of leukemia P-388, pancreas BXPC-3, neuroblast SK-N-SH, thyroid SW1736, lung-NSC NCI-H460, prostate DU-145, and pharynx FADU
- Increases mean arterial blood pressure in vivo
- Decreases tumor blood flow in vivo
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