Phthalic acid and derivatives
Medchemexpress LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester | 150206-05-6 | 99.3% | 25 MG
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell-permeable dye that can label cells by covalently binding to intracellular molecules. It is used to track lymphocyte migration and proliferation.
- Cell permeable dye.
- Labels cells by covalently binding to intracellular molecules.
- Used to track lymphocyte migration and proliferation.
- Excitation at 482 nm.
- Emission at 525 nm.
Medchemexpress LLC Croconic acid disod 50mg
Croconic acid (disodium) (Nacr) can promote cell growth and proliferation by enhancing the expression of genes associated with lysine crotonylation (Kcr) modification Croconic acid holds potential for improving somatic cell nuclear transfer (SCNT) efficiency and optimizing cell culture conditions research[1]
Medchemexpress LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester | 150206-05-6 | 99.3% | 100 MG
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye that labels cells by covalently binding to intracellular molecules. It is used to track lymphocyte migration and proliferation.
- Cell permeable dye
- Labels cells by covalently binding to intracellular molecules
- Used to track lymphocyte migration and proliferation
- Excitation (Ex): 492 nm
- Emission (Em): 517 nm
- Solid, white to off-white appearance
Medchemexpress LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester | 150206-05-6 | 99.3% | 50 MG
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye that labels cells by covalently binding to intracellular molecules. It is used to track lymphocyte migration and proliferation, and is suitable for laboratory research.
- Cell permeable dye.
- Covalently binds to intracellular molecules.
- Used to track lymphocyte migration and proliferation.
- Excitation (Ex): 482 nm.
- Emission (Em): 525 nm.
Apexbio Technology LLC Disodium (R)-2-Hydroxyglutarate 103404-90-6 25mg
Disodium (R)-2-Hydroxyglutarate (CAS 103404-90-6) is an enantiomer of 2-hydroxyglutarate that functions as an inhibitor of ATP synthase a rotary enzyme complex critical for ATP production via oxidative phosphorylation Studies have shown that (R)-2-hydroxyglutarate accumulates in human cancers harboring IDH1 or IDH2 mutations where it suppresses ATP synthase activity leading to tumor cell growth arrest and cell death particularly under glucose-limited conditions In IDH-mutant glioma cells elevated (R)-2-hydroxyglutarate levels reduce oxygen consumption linked to ATP synthase This molecule is used to investigate metabolic vulnerabilities in malignancies with altered 2-hydroxyglutarate metabolism and the role of ATP synthase in cancer cell survival
Apexbio Technology LLC Disodium (R)-2-Hydroxyglutarate 103404-90-6 10mM (in 1mL H2O)
Disodium (R)-2-Hydroxyglutarate (CAS 103404-90-6) is an enantiomer of 2-hydroxyglutarate that functions as an inhibitor of ATP synthase a rotary enzyme complex critical for ATP production via oxidative phosphorylation Studies have shown that (R)-2-hydroxyglutarate accumulates in human cancers harboring IDH1 or IDH2 mutations where it suppresses ATP synthase activity leading to tumor cell growth arrest and cell death particularly under glucose-limited conditions In IDH-mutant glioma cells elevated (R)-2-hydroxyglutarate levels reduce oxygen consumption linked to ATP synthase This molecule is used to investigate metabolic vulnerabilities in malignancies with altered 2-hydroxyglutarate metabolism and the role of ATP synthase in cancer cell survival
Apexbio Technology LLC Disodium (R)-2-Hydroxyglutarate 103404-90-6 100mg
Disodium (R)-2-Hydroxyglutarate (CAS 103404-90-6) is an enantiomer of 2-hydroxyglutarate that functions as an inhibitor of ATP synthase a rotary enzyme complex critical for ATP production via oxidative phosphorylation Studies have shown that (R)-2-hydroxyglutarate accumulates in human cancers harboring IDH1 or IDH2 mutations where it suppresses ATP synthase activity leading to tumor cell growth arrest and cell death particularly under glucose-limited conditions In IDH-mutant glioma cells elevated (R)-2-hydroxyglutarate levels reduce oxygen consumption linked to ATP synthase This molecule is used to investigate metabolic vulnerabilities in malignancies with altered 2-hydroxyglutarate metabolism and the role of ATP synthase in cancer cell survival
Cayman Chemical CyclIc dI-GMPsodIum salt 1mg
A bacterial second messenger and cyclic dinucleotide; an important second messenger in bacteria involved in biofilm formation, motility, virulence, and cell cycling; detected by and binds to STING in eukaryotic cells, activating the innate immune system (Kd = 1.21 µM); induces IFN-β mRNA expression in vitro (EC50 = 537.8 nM) less potently than other cyclic dinucleotides
Medchemexpress LLC Terephthalic acid (Standard) | 100-21-0 | 99.99% | 166.13 | 25 G
Terephthalic acid is an isomer and a precursor of polyester PET, used to make clothing and plastics. It can also be utilized to build skin tumor models by promoting excessive cell proliferation and disrupting the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway. This product is for research use only.
- Used in animal modeling to create skin tumor models
- Metabolized in the body to form calcium terephthalate or calcium hydrogen terephthalate
- Promotes formation of bladder stones
- Promotes excessive cell proliferation
- Induces skin tumor formation by disrupting p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway
- Available in solid form
- Soluble in DMSO
- Stable under recommended storage conditions
- Room temperature shipping
Apexbio Technology LLC Cyclic Pifithrin-α hydrobromide 511296-88-1 50mg
Cyclic Pifithrin- hydrobromide (CAS 511296-88-1) is a synthetic small molecule that functions as an inhibitor of the tumor suppressor protein p53 By blocking p53-dependent transcriptional activation of response genes it interferes with p53-mediated cellular processes such as apoptosis and cell cycle arrest In vitro Cyclic Pifithrin- hydrobromide inhibits p53-dependent apoptosis and DNA damage-induced growth arrest in various cell models without notable effects on p53-deficient cells In vivo it protects mice from the toxic side effects of genotoxic cancer therapies likely through suppression of p53-dependent pathways This compound is utilized in research investigating p53 biology cellular stress responses and modulation of chemotherapeutic toxicity
Medchemexpress LLC Terephthalic acid | 100-21-0 | 99.99% | 166.13 | 50 G
Terephthalic acid is an isomer and a precursor of polyester PET, used in clothing and plastics. It can also be utilized to build skin tumor models and promote excessive cell proliferation by disrupting the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway. In vivo, it can lead to bladder stone formation in animal models, particularly in weanling mice at higher doses.
- Isomer and precursor of polyester PET
- Used to build skin tumor models
- Promotes excessive cell proliferation
- Induces skin tumor formation
- Metabolized to form calcium terephthalate, potentially leading to bladder stone formation
Apexbio Technology LLC Cyclic Pifithrin-α hydrobromide 511296-88-1 25mg
Cyclic Pifithrin- hydrobromide (CAS 511296-88-1) is a synthetic small molecule that functions as an inhibitor of the tumor suppressor protein p53 By blocking p53-dependent transcriptional activation of response genes it interferes with p53-mediated cellular processes such as apoptosis and cell cycle arrest In vitro Cyclic Pifithrin- hydrobromide inhibits p53-dependent apoptosis and DNA damage-induced growth arrest in various cell models without notable effects on p53-deficient cells In vivo it protects mice from the toxic side effects of genotoxic cancer therapies likely through suppression of p53-dependent pathways This compound is utilized in research investigating p53 biology cellular stress responses and modulation of chemotherapeutic toxicity
Apexbio Technology LLC Cyclic Pifithrin-α hydrobromide 511296-88-1 10mg
Cyclic Pifithrin- hydrobromide (CAS 511296-88-1) is a synthetic small molecule that functions as an inhibitor of the tumor suppressor protein p53 By blocking p53-dependent transcriptional activation of response genes it interferes with p53-mediated cellular processes such as apoptosis and cell cycle arrest In vitro Cyclic Pifithrin- hydrobromide inhibits p53-dependent apoptosis and DNA damage-induced growth arrest in various cell models without notable effects on p53-deficient cells In vivo it protects mice from the toxic side effects of genotoxic cancer therapies likely through suppression of p53-dependent pathways This compound is utilized in research investigating p53 biology cellular stress responses and modulation of chemotherapeutic toxicity
Medchemexpress LLC Terephthalic acid | 100-21-0 | 99.99% | 166.13 | 100 MG
Terephthalic acid is an isomer and precursor of polyester PET, widely used in textiles and plastics. It is also utilized in biological research for developing skin tumor models. This compound promotes cell proliferation and can induce skin tumor formation by interfering with the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway.
- Isomer and precursor of polyester PET
- Used in clothing and plastics
- Can be used to build skin tumor models
- Promotes excessive cell proliferation
- Induces skin tumor formation
- May lead to bladder stone formation at higher doses
Apexbio Technology LLC Cyclic Pifithrin-α hydrobromide 511296-88-1 5mg
Cyclic Pifithrin- hydrobromide (CAS 511296-88-1) is a synthetic small molecule that functions as an inhibitor of the tumor suppressor protein p53 By blocking p53-dependent transcriptional activation of response genes it interferes with p53-mediated cellular processes such as apoptosis and cell cycle arrest In vitro Cyclic Pifithrin- hydrobromide inhibits p53-dependent apoptosis and DNA damage-induced growth arrest in various cell models without notable effects on p53-deficient cells In vivo it protects mice from the toxic side effects of genotoxic cancer therapies likely through suppression of p53-dependent pathways This compound is utilized in research investigating p53 biology cellular stress responses and modulation of chemotherapeutic toxicity