Aminophenols
Medchemexpress LLC RGX-104 (hydrochloride) | 610318-03-1 | 99.9% | 632.54 | 10 MG
RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. It is for research use only and not sold to patients.
- LXR agonist
- Modulates innate immunity via transcriptional activation of the ApoE gene
- Oral administration significantly suppresses the growth of multiple cancer types (e.g., lung cancer, melanoma, glioblastoma, ovarian, renal cell, triple-negative breast, and colon cancer) in animals with palpable tumors.
- Can cause partial or complete tumor regression in some instances.
Cayman Chemical NG-amino-L-Arginine (hydrochloride), Purity: ≥97%, CAS: 1031799-40-2, 25 mg
Inhibits nNOS, iNOS, and eNOS (Ki = 0.3, 3, and 2.5 μM, respectively); can be used both in cell culture and in vivo
Medchemexpress LLC SKI-178 | 1259484-97-3 | 99.29% | 100 MG
SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. It exhibits cytotoxicity at IC50 concentrations ranging from 0.1 to 1.8 μM in various cancer cell lines, including MTR3, NCI-ADR, and HL60/VCR cells. SKI-178 induces apoptosis in human acute myeloid leukemia cell lines in a CDK1-dependent manner and has been shown to inhibit leukemic progression in an MLL-AF9 mouse model.
- Potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2
- Exhibits cytotoxicity in multiple cancer cell lines
- Induces apoptosis in human acute myeloid leukemia cell lines
- Inhibits leukemic progression in MLL-AF9 mouse model
- Purity of 99.29%
- Soluble in DMSO for in vitro experiments
- Formulations suitable for oral and intraperitoneal injection for in vivo studies
Medchemexpress LLC Imiloxan hydrochloride | 81167-22-8 | 98.5% | 280.75 g/mol | C14H17ClN2O2 | 5 MG
Imiloxan hydrochloride is a potent, selective α2B-adrenoceptor antagonist used in pharmacological research to probe α2-adrenergic receptor subtype function. It is supplied as a characterized solid with defined purity and molecular weight for use in receptor-binding studies, in vitro assays, and in vivo experiments.
- Selective α2B-adrenoceptor antagonist
- High purity suitable for research applications
- Supplied in small research pack sizes for lab use
- Supported by analytical data (HNMR, LC-MS)
- Provided with SDS, COA, and handling instructions
Medchemexpress LLC DC-Chol hydrochloride | 166023-21-8 | >99.9% | 537.26 | 250 MG
DC-Chol hydrochloride is a cationic lipid that inhibits Aβ40 fibril formation and amyloidogenesis of oxidized hCT. It enhances the body's immune response to antigens by inducing the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. This compound is also utilized as a gene delivery vector.
- Can inhibit Aβ40 fibril formation
- Strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner
- Induces production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines
- Enhances the body's immune response to antigens
- Used as a gene delivery vector
- Can be used in research for hepatitis B vaccines to improve vaccine immunity
Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 25 MG
Biotin-4-aminophenol is a biotin-phenol analog. It is designed for research use only and generates free radicals that conjugate to tyrosine residues in proteins more efficiently and selectively than previously reported BP1. This product is suitable for various laboratory applications.
- Generates free radicals
- Efficiently conjugates to tyrosine residues in proteins
- More selective than BP1
- For research use only
- White to off-white solid appearance
Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | 99.9% | 100 MG
Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker and a potent antiarrhythmic agent. It can be used for the research of pediatric arrhythmias and also functions as an antiepileptic agent.
- Blocks β-receptors
- Blocks potassium KCNH2 channels
- Suitable for research on pediatric arrhythmias
- Functions as an antiepileptic agent
Medchemexpress LLC Bestatin-d7 (hydrochloride) | 97.7% | 1 MG
Bestatin-d7 (hydrochloride) is a deuterium-labeled version of Bestatin (hydrochloride). Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, primarily utilized in cancer research.
- Deuterium labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase
Medchemexpress LLC SAR7334 hydrochloride | 1333207-63-8 | 98.0% | 440.79 g/mol | C21H24Cl3N3O | 10 MG
SAR7334 hydrochloride is the hydrochloride salt of SAR7334, a potent and selective small-molecule inhibitor of the TRPC6 ion channel. It inhibits TRPC6 currents with an IC50 of 7.9 nM and is supplied as a high-purity research reagent for biochemical and cellular studies.
- Potent TRPC6 inhibitor (IC50 7.9 nM).
- Hydrochloride salt form for improved stability and solubility.
- Purity: 98.0% (as supplied).
- Molecular weight: 440.79 g/mol.
- Available as milligram quantities and as a 10 mM solution in DMSO.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC PKI-179 hydrochloride | 1463510-35-1 | 99.66% | 525.00 | 10 MG
PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor. It exhibits activity over various PI3K isoforms and mTOR, along with E545K and H1047R. This compound demonstrates anti-tumor activity in vivo.
- Potent and orally active dual PI3K/mTOR inhibitor
- Inhibits PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR
- Shows activity over E545K and H1047R
- Exhibits anti-tumor activity in vivo
Medchemexpress LLC Acetaminophen | 103-90-2 | 99.97% | C8H9NO2 | 10 G
Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor and a widely used antipyretic and analgesic agent. It is also a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor that induces ferroptosis and can lead to acute liver injury in mice models.
- Selective COX-2 inhibitor with an IC50 of 25.8 μM
- Widely used as an antipyretic and analgesic
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor
- Induces ferroptosis
- Can lead to acute liver injury in mice models
Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | 99.9% | 5 MG
Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. It is a potent antiarrhythmic agent used for the research of pediatric arrhythmias.
- Orally active, non-selective β-adrenergic receptor blocker
- Potent antiarrhythmic agent
- Blocks β-receptors and potassium KCNH2 channels
- Suitable for research on pediatric arrhythmias
- Classified as an antiepileptic agent
Medchemexpress LLC Sotalol hydrochloride | 959-24-0 | MFCD00242937 | 99.9% | 308.82 g/mol | C12H21ClN2O3S | 10 MG
Sotalol hydrochloride is an orally active, non-selective β-adrenergic receptor blocker with class III antiarrhythmic activity used in cardiovascular and electrophysiology research. It is supplied as a characterized research chemical with high purity and documented analytical data.
- High purity as determined by LCMS (≈99.9%).
- Molecular weight 308.82 g/mol and molecular formula C12H21ClN2O3S.
- Used to study β-receptor blockade and cardiac repolarization (potassium channel) effects.
- Supplied in small research pack sizes and solution formats (for example, 10 MG solid or 10 mM/1 mL solution).
Medchemexpress LLC Iccb-19 hydrochloride | 1803605-68-6 | 99.3% | 291.84 | 1 ML
ICCB-19 hydrochloride is an inhibitor of TRADD (TNFRSF1A associated via death domain). It binds to the N-terminal domain of TRADD (TRADD-N), which prevents TRADD-N from binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride also acts as an indirect inhibitor of RIPK1 kinase activity and effectively induces autophagy and the degradation of long-lived proteins.
- TRADD (TNFRSF1A associated via death domain) inhibitor.
- Binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2.
- Indirect inhibitor of RIPK1 kinase activity.
- Induces autophagy and degradation of long-lived proteins.
- Inhibits Bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM (In Vitro).
- Reduces inflammatory responses in Tradd-/- mice (In Vivo).
eMolecules 101-18-8 | 3-Hydroxydiphenylamine | Combi-Blocks | MFCD00002262 | 185.226 | C12H11NO | 98.000 | Oc1cccc(Nc2ccccc2)c1 | 1g | 290690778
3-Hydroxydiphenylamine | Combi-Blocks | 101-18-8 | MFCD00002262 | 185.226 | C12H11NO | 98.000 | Oc1cccc(Nc2ccccc2)c1 | 1g | 290690778