Aminophenols
Medchemexpress LLC AFM32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 1 ML
AFM32a hydrochloride, also known as PAD2-IN-1 hydrochloride, is a potent and selective benzimidazole-based derivative that inhibits protein arginine deiminase 2 (PAD2). It demonstrates high selectivity, being 95-fold more selective for PAD2 over PAD4 and 79-fold more selective over PAD3.
- Potent and selective PAD2 inhibitor.
- Exhibits superior selectivity over PAD4 and PAD3.
- Effective in inhibiting histone H3 citrullination in HEK293T/PAD2 cells.
Medchemexpress LLC dAURK-4 (hydrochloride) | 99.4% | 1071.93 | 100 MG
dAURK-4 hydrochloride is a potent and selective PROTAC AURKA (Aurora A) degrader. This derivative of Alisertib exhibits anticancer effects and is composed of a ligand for target protein, a linker, and a ligand for E3 ligase.
- Potent and selective degrader of AURKA (Aurora A)
- Exhibits anticancer effects
- Degrades AURKA in a dose-dependent manner (125-1000 nM; 4-24 hours)
- Inhibits protein level of AURKA (Aurora A) in MM.1S cells
Medchemexpress LLC DC-Chol hydrochloride | 166023-21-8 | >99.9% | 537.26 | 250 MG
DC-Chol hydrochloride is a cationic lipid that inhibits Aβ40 fibril formation and amyloidogenesis of oxidized hCT. It enhances the body's immune response to antigens by inducing the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. This compound is also utilized as a gene delivery vector.
- Can inhibit Aβ40 fibril formation
- Strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner
- Induces production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines
- Enhances the body's immune response to antigens
- Used as a gene delivery vector
- Can be used in research for hepatitis B vaccines to improve vaccine immunity
Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 100 MG
Biotin-4-aminophenol is a biotin-phenol analog that generates free radicals. It conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1.
- Biotin-phenol analog
- Generates free radicals
- Efficiently conjugates to tyrosine residues in proteins
- More selective than BP1
- Molecular weight: 335.42
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC V-0219 hydrochloride | 2922283-73-4 | 99.39% | C20H26ClF3N4O2 | 25 MG
V-0219 hydrochloride (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). It can be used for obesity-associated diabetes research.
- Orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R)
- Can be used for obesity-associated diabetes research
- IC50 and target: GLP-1R
Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 25 MG
Biotin-4-aminophenol is a biotin-phenol analog. It is designed for research use only and generates free radicals that conjugate to tyrosine residues in proteins more efficiently and selectively than previously reported BP1. This product is suitable for various laboratory applications.
- Generates free radicals
- Efficiently conjugates to tyrosine residues in proteins
- More selective than BP1
- For research use only
- White to off-white solid appearance
Sigma Aldrich Fine Chemicals Biosciences SKI II >=98% (HPLC), solid | 312636-16-1 | MFCD00733553 | 50MG
SKI II >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 302.78 | 312636-16-1 | MFCD00733553 | 50MG
eMolecules JANEX-1 | 202475-60-3 | MFCD01862614 | 1g
AstaTech | JANEX-1 | 1g | 290663216 | 44061 | 95.000 | 202475-60-3 | MFCD01862614 | 297.314 | C16H15N3O3
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Medchemexpress LLC MELK-8a hydrochloride | 2096992-20-8 | 99.3% | 469.02 g/mol | C25H33ClN6O | 25 MG
MELK-8a hydrochloride is a potent small-molecule inhibitor of maternal embryonic leucine zipper kinase (MELK) with a reported IC50 of 2 nM. Supplied as the hydrochloride salt with high chemical purity, it is intended for research use in biochemical and cellular studies targeting MELK-dependent pathways.
- Potent MELK inhibition with an IC50 of 2 nM.
- Hydrochloride salt for improved stability and handling.
- High purity suitable for biochemical and cellular assays.
- Molecular weight 469.02 g/mol and formula C25H33ClN6O.
- Soluble in DMSO; solution formats available for convenient dosing.
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC Guvacine hydrochloride | 6027-91-4 | MFCD00055191 | 99.9% | 163.60 g/mol | C6H10ClNO2 | 1 ML
Guvacine hydrochloride is a GABA transporter inhibitor used in neuroscience research to investigate GABAergic signaling and transporter pharmacology. It is supplied with documented purity, molecular data, and recommended storage conditions to support reliable in vitro experiments.
- Inhibits GABA transporter activity with reported IC50 values for multiple transporter subtypes.
- Supplied as a ready-to-use 10 mM solution in DMSO (1 ML) for immediate use in assays.
- Also available as a solid for custom preparation and long-term storage.
- High reported purity supports reproducible experimental results.
- Storage guidance provided to maintain stability of solid and solution forms.
Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 | C26H30ClN5O2S | 10 MG
CGP71683 hydrochloride is the hydrochloride salt of a selective neuropeptide Y Y5 receptor antagonist used as a research tool in neuroscience and endocrinology. It is supplied as a high-purity solid for non-clinical laboratory use, with supporting datasheet and certificate of analysis available.
- Selective antagonist for the neuropeptide Y Y5 receptor (Ki ~1.3 nM).
- High reported purity, 99.4%.
- Molecular weight 512.07 g/mol; chemical formula C26H30ClN5O2S.
- CAS number 192322-50-2 for unambiguous identification.
- Solid powder suitable for dissolution in appropriate solvents for assays.
- Supplied with datasheet and certificate of analysis for quality assurance.
- Available in small milligram pack sizes for screening and mechanistic studies.
Cayman Chemical NGaminoLArginine hydrochlori
Inhibits nNOS, iNOS, and eNOS (Ki = 0.3, 3, and 2.5 μM, respectively); can be used both in cell culture and in vivo
Chemscene ChemScene | 2,3-Diaminophenol | 10G | CS-W005863 | 0.97 | 59649-56-8| MFCD00075199 | 124.14
ChemScene | 2,3-Diaminophenol | 10G | CS-W005863 | 0.97 | 59649-56-8| MFCD00075199 | 124.14
Medchemexpress LLC RS100329 hydrochloride (2,4(1H,3H)-pyrimidinedione derivative) | 1215654-26-4 | 99.6% | 462.89 | C20H26ClF3N4O3 | 1 ML
RS100329 hydrochloride is a potent, selective α1A-adrenoceptor antagonist provided for in vitro receptor pharmacology and biochemical assays. It is available as a pre-made 10 mM solution in DMSO (1 mL) and in multiple solid sizes, with accompanying analytical documentation for research use.
- Potent, selective α1A-adrenoceptor antagonist suitable for in vitro studies.
- Available as 10 mM DMSO solution (1 mL) and as solid in multiple mg sizes.
- High purity (99.57%) appropriate for biochemical assays.
- Molecular weight 462.89 and formula C20H26ClF3N4O3.
- Supplied with data sheet, certificate of analysis, and safety data sheet.
- Intended for research use; follow laboratory safety and SDS guidance.
Sigma Aldrich Fine Chemicals Biosciences 4-Nitrophenol-2,3,5,6-d4 98 atom % D, 98% (CP) | 93951-79-2 | MFCD00143352 | 250MG
4-Nitrophenol-2,3,5,6-d4 98 atom % D, 98% (CP) | Purity: 98% (CP) | Mol Wt: 143.13 | 93951-79-2 | MFCD00143352 | 250MG