Aminophenols
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 50MG
Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 50MG
Medchemexpress LLC Bepridil hydrochloride | 68099-86-5 | MFCD00065498 | 100.0% | 403.0 g/mol | C24H35ClN2O | 1 ML
Bepridil hydrochloride is the hydrochloride salt of bepridil, a non-selective calcium channel blocker used in research to probe cardiac ion channels and antianginal mechanisms. Supplied for research and analytical applications, it is available as a solid and as a prepared solution.
- Non-selective calcium channel blocker used in electrophysiology and pharmacology studies.
- Hydrochloride salt form enhances solubility for assays.
- Available as solid and as a 10 mM solution in DMSO for ready-to-use experiments.
- High purity (~99.98%) appropriate for analytical standards.
- Well-characterized identifiers: CAS 68099-86-5; molecular weight 403.0 g/mol.
Medchemexpress LLC Scopine hydrochloride | 85700-55-6 | 99.7% | 1 ML
Scopine hydrochloride, also known as 6,7-Epoxytropine hydrochloride, is a metabolite of Scopolamine and a brain-targeting compound. It significantly increases the brain exposure of Chlorambucil and enhances its anti-glioma activity. It can be utilized in targeted therapy research for brain gliomas.
- Metabolite of Scopolamine
- Brain-targeting compound
- Increases brain exposure of Chlorambucil
- Enhances anti-glioma activity
- Suitable for targeted therapy research for brain gliomas
Medchemexpress LLC ST-836 (hydrochloride) | 1415564-68-9 | C23H35ClN4OS | 25 MG
ST-836 hydrochloride is a potent dopamine receptor ligand with Ki values of 4.5 nM and 132 nM for D3 and D2 receptors, respectively. It has potential for Parkinson's disease. The salt form typically offers enhanced water solubility and stability compared to the free form, while maintaining comparable biological activity at equivalent molar concentrations.
- Potent dopamine receptor ligand
- Targets D3 receptor (Ki: 4.5 nM)
- Targets D2 receptor (Ki: 132 nM)
- Potential for Parkinson's disease treatment
- Enhanced water solubility and stability (salt form)
- Store solid at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
Medchemexpress LLC LY294002 hydrochloride | 934389-88-5 | MFCD01530034 | 99.9% | 343.8 g/mol | C19H18ClNO3 | 50 MG
LY294002 hydrochloride is the hydrochloride salt of LY294002, a broad-spectrum phosphoinositide 3-kinase (PI3K) inhibitor supplied as a high-purity powder for research use only. It is commonly used in biochemical and cell-based studies to probe PI3K-dependent signaling, apoptosis, and autophagy pathways.
- Broad-spectrum PI3K inhibitor, active against multiple PI3K isoforms.
- Potent biochemical activity with submicromolar IC50 values for key isoforms.
- High purity suitable for biochemical and cell-based assays (reported ~99.9%).
- Hydrochloride salt form with improved solubility in polar solvents.
- Supplied as a solid powder for convenient weighing and storage.
- Commonly used to study apoptosis, autophagy, and cell signaling.
- CAS number 934389-88-5 and molecular weight ≈343.8 g/mol.
- Available in small research pack sizes including 50 MG.
Medchemexpress LLC Acetaminophen | 103-90-2 | 99.97% | C8H9NO2 | 50 MG
Acetaminophen (Standard) is the analytical standard of Acetaminophen, intended for research and analytical applications. Also known as Paracetamol, it is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM, and a widely used antipyretic and analgesic agent. It also acts as a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Analytical standard grade
- Reference standard supplied assay
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC
- Suitable for GC
- Suitable for MS
Medchemexpress LLC AP14145 hydrochloride | 2387505-59-9 | 98.3% | 5 MG
AP14145 hydrochloride is a hydrochloride salt of a small-molecule negative allosteric modulator of KCa2 (SK) channels. It shows in vitro potency near 1.1 μM for KCa2.2 (SK2) and KCa2.3 (SK3) and has demonstrated prolongation of atrial effective refractory period and antiarrhythmic effects in preclinical models. Supplied as a 5 MG vial with reported purity of 98.3%.
- Negative allosteric modulator of KCa2 (SK) channels
- In vitro potency around 1.1 μM for SK2 and SK3
- Demonstrated atrial electrophysiology effects in vivo
- Hydrochloride salt form for improved handling
- High reported purity (98.3%)
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 | 1 ML
CBL0137, a curaxin compound, is a histone chaperone that facilitates chromatin transcription (FACT) inhibitor. It downregulates NF-κB, activates p53, and restores both histone H3 acetylation and trimethylation. CBL0137 acts as an anticancer agent by inducing cancer cell apoptosis. It is intended for research use only and not for sale to patients.
- Histone chaperone FACT inhibitor.
- Downregulates NF-κB and activates p53.
- Restores histone H3 acetylation and trimethylation.
- Induces cancer cell apoptosis.
- Efficacious in preclinical glioblastoma models.
- Reduces colony formation with Gemcitabine in pancreatic cancer cells.
- Modulates RRM1 and RRM2 gene expression.
- Suppresses tumor growth in various xenografts.
Medchemexpress LLC CX-6258 hydrochloride | 1353859-00-3 | 99.0% | 498.40 | 50 MG
CX-6258 hydrochloride is a potent and kinase-selective pan-Pim kinases inhibitor, demonstrating IC50s of 5 nM for Pim-1, 25 nM for Pim-2, and 16 nM for Pim-3.
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins, bad and 4e-bp1, at specific pim kinase sites.
- Treatment diminishes steady-state levels of ectopic nkx3.1 in pc3 cells.
- Treatment results in a significant reduction in nkx3.1 half-life.
- Exhibits robust in vivo efficacy in two pim kinase-driven tumor models.
- Demonstrates dose-dependent efficacy, producing 45% tumor growth inhibition at 50 mg/kg and 75% tumor growth inhibition at 100 mg/kg.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 100 MG
Ozanimod hydrochloride is the hydrochloride salt of ozanimod (RPC-1063), a selective sphingosine 1-phosphate (S1P) receptor modulator used in pharmacological and preclinical research. Supplied as a solid powder and as DMSO solution formats; intended for research use only.
- Hydrochloride salt form suitable for research applications.
- CAS number 1618636-37-5.
- Molecular formula C23H25ClN4O3.
- Molecular weight 440.92 g/mol.
- Purity approximately 98.1% by HPLC.
- Available as solid and as DMSO solution for biochemical assays.
- For research use only; not for human use.
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 1 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This product is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis, multiple sclerosis, lupus, and ulcerative colitis.
- Potent and selective PAD2 inhibitor.
- Inhibits H3 citrullination.
- Useful for cancer research.
- Useful for autoimmune disease research.
- Suppresses NLRP3 signaling.
- Decreases airway remodeling.
- Shows low cell cytotoxicity.
Medchemexpress LLC Afm-30a hydrochloride | 99.8% | 502.97 | 50 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor with an EC50 value of 9.5 μM for PAD2. It also inhibits H3 citrullination with an EC50 value of 0.4 μM. This compound is intended for research related to certain cancers and various autoimmune diseases such as rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis. It exhibits low cytotoxicity in HEK293T/PAD2 cells and can suppress NLRP3 signaling and decrease airway remodeling in PAD2-/- transgenic mice.
- Potent protein arginine deiminase 2 (PAD2) inhibitor.
- Excellent PAD2-selectivity.
- Inhibits H3 citrullination.
- Can be used for research of certain cancers and autoimmune diseases (rheumatoid arthritis, multiple sclerosis, lupus, ulcerative colitis).
- Low cytotoxicity in HEK293T/PAD2 cells.
- Suppresses NLRP3 signaling and decreases airway remodeling in PAD2-/- transgenic mice.