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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378467 LTGO-33 10MM 1ML
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Medchemexpress LLC ODN 4084-F sodium | 1934318-44-1 | DNA, d(P-thio)(C-C-T-G-G-A-T-G-G-G-A-A）, sodium salt | 1 MG
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ODN 4084-F sodium is a class B ('broadly-active') inhibitory ODN. It acts as a potent inhibitor of TLR9-induced B cells and macrophages. This product is a white to off-white solid.
- Class B ('broadly-active') inhibitory ODN
- Potent inhibitor of TLR9-induced B cells and macrophages
- Solid appearance
- White to off-white color
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![eMolecules 1065010-87-8 | Potassium Cyclopropyltrifluoroborate | Accela ChemBio (ASD) | MFCD09265031 | 147.980 | C3H5BF3K | 95.000 | [K+].F[B-](F)(F)C1CC1 | 25g | 454121313](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000159440.jpg-250.jpg)
eMolecules 1065010-87-8 | Potassium Cyclopropyltrifluoroborate | Accela ChemBio (ASD) | MFCD09265031 | 147.980 | C3H5BF3K | 95.000 | [K+].F[B-](F)(F)C1CC1 | 25g | 454121313
Potassium Cyclopropyltrifluoroborate | Accela ChemBio (ASD) | 1065010-87-8 | MFCD09265031 | 147.980 | C3H5BF3K | 95.000 | [K+].F[B-](F)(F)C1CC1 | 25g | 454121313
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430142 VARI FLUOR 425 SE 1MG
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eMolecules 23761-23-1 | 3-Oxocyclobutanecarboxylic acid | Ambeed | MFCD00100900 | 114.100 | C5H6O3 | 98.000 | OC(=O)C1CC(=O)C1 | 10g | 490494921
3-Oxocyclobutanecarboxylic acid | Ambeed | 23761-23-1 | MFCD00100900 | 114.100 | C5H6O3 | 98.000 | OC(=O)C1CC(=O)C1 | 10g | 490494921
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eMolecules SODIUM DODECYLSULFATE MI 250G
5000159271 SODIUM DODECYLSULFATE MI 250G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430683 HP POLYFAST TRANSFEC 5ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430725 VARI FLUOR 647 SE 1MG
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Medchemexpress LLC Rho-Kinase-IN-2 | 2573071-18-6 | C20H25FN4O2 | 100 MG
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Rho-Kinase-IN-2 (Compound 23) is an orally active, selective, and CNS-penetrant Rho Kinase (ROCK) inhibitor with a ROCK2 IC50 of 3 nM, making it suitable for Huntington's research. It increases AKT phosphorylation and decreases MYPT1 phosphorylation both in vitro and in vivo. This product is intended for research use only.
- Orally active, selective, and CNS-penetrant ROCK inhibitor
- Targeted inhibition of ROCK2 with an IC50 of 3 nM
- Increases AKT phosphorylation and decreases MYPT1 phosphorylation in A7r5 and PANC1 cells
- Demonstrates dose- and time-dependent ROCK1 and ROCK2 target engagement in vivo
- Shows excellent tolerability in mouse models
- Decreases mean arterial, systolic, and diastolic blood pressure and heart rate in CD1 mice
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Medchemexpress LLC Boeravinone E | 137787-00-9 | 1 MG
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Boeravinone E is a natural product isolated from *Boerhaavia diffusa L*, classified as a flavonoid, isoflavone, phenol, and polyphenol. It exhibits spasmolytic activity and is intended for research use only.
- Purity of 99.73%
- Molecular weight of 328.27
- Chemical formula: C17H12O7
- Appears as a solid
- Color is white to yellow
- Classified as a flavonoid, isoflavone, phenol, and polyphenol
- Initially sourced from *Boerhaavia diffusa L* plants
- Ships at room temperature in continental US; may vary elsewhere
- Store at 4°C, protected from light. In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
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![Medchemexpress LLC Acetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt | 1459687-96-7 | 99.5% | 364.35 g/mol | C16H13N4NaO3S | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000212884.png-250.jpg)
Medchemexpress LLC Acetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt | 1459687-96-7 | 99.5% | 364.35 g/mol | C16H13N4NaO3S | 1 ML
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GJ103 sodium is the sodium salt form of a small-molecule read-through compound that promotes translational read-through of premature stop codons. It is provided for research use in studies of genetic disorders caused by nonsense mutations and is available as a high-purity solid or as a concentrated solution in DMSO.
- Induces read-through of premature stop codons for genetic research.
- Water-soluble sodium salt form enables easier handling and formulation.
- High purity (reported ~99.5%) suitable for research applications.
- Offered as a 10 mM solution in DMSO and in multiple solid mass sizes.
- Molecular weight approximately 364.35 g/mol.
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Apexbio Technology LLC Buspirone HCl 33386-08-2 10mM (in 1mL DMSO)
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Buspirone hydrochloride (CAS 33386-08-2) is a selective agonist of the 5-HT1A serotonin receptor subtype engaging central nervous system sites to modulate serotonergic neurotransmission Through its specific interaction with 5-HT1A receptors buspirone hydrochloride influences neurochemical signaling pathways associated with anxiety and mood regulation This compound is widely utilized as a research tool in studies investigating the neurobiological mechanisms underlying anxiety and depression as well as the interplay between central neurotransmitter systems and emotional processing
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Medchemexpress LLC Menin-MLL inhibitor MI-2 | 1271738-62-5 | C18H25N5S2 | 1 ML
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Menin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor. It effectively downregulates target genes like HOXA9 and MEIS1, leading to inhibition of leukemia cell proliferation and induction of apoptosis and differentiation. This compound shows promise in the research of MLL-rearranged acute leukemias, including AML and ALL, with an IC50 of 446 nM and a Ki value of 158 nM.
- Competitive and selective Menin-MLL interaction inhibitor
- Downregulates expression of target genes (HOXA9, MEIS1)
- Inhibits proliferation of leukemia cells
- Induces apoptosis and differentiation
- Promising for research of MLL-rearranged acute leukemias
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Medchemexpress LLC N-[4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-1-(2-furanylmethyl)-5-oxo-pyrrolidinecarboxamide | 2784577-71-3 | MFCD00701047 | C24H19ClN4O4 | 1 ML
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RLX-33 is a potent, selective, and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist. This compound blocks relaxin-3-induced ERK1/2 phosphorylation and can prevent the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats, making it suitable for metabolic syndrome research.
- Potent and selective RXFP3 antagonist
- Blood-brain barrier penetrant
- Blocks relaxin-3-induced ERK1/2 phosphorylation
- Attenuates R3/I5-induced feeding
- Good brain penetration
- Highly protein-bound in rat plasma
- Useful for metabolic syndrome research
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Medchemexpress LLC 3,7-bis(4-methoxybenzyl)-3,7-dihydro-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one | 1070773-09-9 | MFCD30489740 | 99.6% | 428.44 g·mol⁻¹ | C23H20N6O3 | 1 ML
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RK-33 is a small-molecule inhibitor of the RNA helicase DDX3 used for preclinical and molecular biology research. It inhibits DDX3 helicase activity and is intended for laboratory studies investigating RNA processing, translation, cell-cycle regulation, and related pathways.
- Inhibits DDX3 RNA helicase activity for mechanistic studies.
- Available as a 10 mM solution in DMSO (1 mL) suitable for in vitro assays.
- High purity (≈99.6%) to minimize off-target effects.
- Soluble in DMSO and formulatable for in vivo dosing with PEG300/saline.
- Recommended storage conditions for powder and solutions to preserve stability.
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