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Filtered Search Results
Medchemexpress LLC Tris(hydroxymethyl)aminomethane | 77-86-1 | 99.9% | 500 G
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THAM (Tris) is a biologically inert amino alcohol with low toxicity that buffers carbon dioxide and acids both in vitro and in vivo. It is an effective amine compound for pH control in the physiological range. It has been shown to reduce arterial carbon dioxide tension (PaCO2) levels and increase pH above 7.4 during infusion in pigs.
- Biologically inert amino alcohol with low toxicity
- Buffers carbon dioxide and acids
- Effective for pH control in the physiological range
- Reduces arterial carbon dioxide tension
- Increases pH during infusion
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Apexbio Technology LLC Levobetaxolol HCl 116209-55-3 10mM (in 1mL DMSO)
Levobetaxolol HCl (CAS 116209-55-3) is a selective -adrenergic receptor antagonist It demonstrates a high binding affinity for human 1-adrenergic receptors (K sub i /sub 0 76 nM) and lower affinity for 2-adrenergic receptors (K sub i /sub 32 6 nM) indicating pronounced selectivity toward the 1 subtype Through inhibition of -adrenergic signaling Levobetaxolol HCl is utilized in research investigating cardiovascular regulation receptor pharmacology and the molecular mechanisms underlying 1-adrenergic blockade Its well-characterized receptor selectivity supports its use in dissecting -adrenergic pathway contributions in preclinical models
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eMolecules 126-33-0 | Sulfolane | Oakwood Chemicals | MFCD00005484 | 120.170 | C4H8O2S | 99.000 | O=S1(=O)CCCC1 | 1kg | 480131568
Sulfolane | Oakwood Chemicals | 126-33-0 | MFCD00005484 | 120.170 | C4H8O2S | 99.000 | O=S1(=O)CCCC1 | 1kg | 480131568
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Apexbio Technology LLC Tolazoline HCl 59-97-2 10mM (in 1mL DMSO)
Tolazoline hydrochloride (CAS 59-97-2) is a small molecule that functions as a competitive antagonist at -adrenergic receptors exhibiting non-selective affinity for both 1- and 2-adrenoceptor subtypes By inhibiting endogenous catecholamine binding tolazoline modulates vasomotor tone and vascular smooth muscle contraction This pharmacological profile enables researchers to investigate adrenergic signaling pathways and the physiological roles of -adrenergic receptors Tolazoline HCl is widely utilized in studies of vascular function receptor pharmacology and the characterization of sympathetic nervous system mechanisms
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Medchemexpress LLC 2-pyridinecarboxamidoxime | 1772-01-6 | MFCD00085159 | 95.0% | 137.14 g/mol | C6H7N3O | 100 G
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2-Pyridinecarboxamidoxime is a solid small-molecule synthetic intermediate (CAS 1772-01-6; C6H7N3O; MW 137.14 g/mol) commonly used as a building block in pharmaceutical and organic synthesis.
- Used as a synthetic intermediate in pharmaceutical and medicinal chemistry.
- Solid form for straightforward weighing and storage.
- Molecular formula C6H7N3O and molecular weight 137.14 g/mol.
- Typical purity ≥95% suitable for synthetic applications.
- Available in multiple laboratory pack sizes for scale flexibility.
- Compatible with standard organic synthesis workflows.
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Medchemexpress LLC Maltol | 118-71-8 | MFCD00006578 | >=99.0% | 126.11 | 100 G
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Maltol is an aromatic compound with antioxidant properties. It enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol inhibits oxidative damage in nerve cells and helps prevent diabetic peripheral neuropathy (DPN). It is also widely used as a safe flavoring agent and food preservative. Additionally, Maltol acts as a metal ion chelator, useful in catalysis, cosmetics, and medicine.
- Antioxidant agent
- Enhances neural function by mitigating oxidative stress and cell apoptosis
- Inhibitor of oxidative damage in nerve cells
- Effective in preventing diabetic peripheral neuropathy (DPN)
- Used as a flavoring agent and food preservative
- Metal ion chelator
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Medchemexpress LLC E/Envelope Dengue v 50ug
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E/Envelope Protein Dengue virus 2 (102a a P pastoris His) is the recombinant Virus-derived E/Envelope protein expressed by P pastoris with C-His labeled tag
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Medchemexpress LLC Mao-in-m30 dihydrochloride | 64821-19-8 | MFCD20488063 | 99.3% | C14H16Cl2N2O | 10MG
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MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain-selective irreversible inhibitor of monoamine oxidase A and B (MAO-A and MAO-B). It also acts as a potent iron chelator and radical scavenger, showing neuroprotective and neurorestorative effects in preclinical models, and contains an alkyne moiety suitable for click-chemistry labeling.
- Orally active and brain-permeable inhibitor of MAO-A and MAO-B.
- Potent inhibition (MAO-A IC50 = 37 nM; MAO-B IC50 = 57 nM).
- Functions as an iron chelator and radical scavenger.
- Demonstrates neuroprotective and neurorestorative effects in preclinical models.
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Supplied as a dihydrochloride salt with high purity (~99.3%).
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Medchemexpress LLC Ethyl N-(2,2-diphenylacetyl)carbamate | 302841-86-7 | MFCD20270619 | 99.9% | 283.32 g/mol | C17H17NO3 | 1 ML
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Ro 01-6128 is a small-molecule positive allosteric modulator of metabotropic glutamate receptor 1 (mGluR1) supplied for research applications. It is provided as a 10 mM solution in DMSO or as solid quantities, and has documented solubility, storage, and purity data to support in vitro and in vivo studies.
- Positive allosteric modulator of mGluR1 for receptor pharmacology studies.
- High purity reported at 99.87%.
- Molecular weight 283.32 g/mol; formula C17H17NO3.
- Available as 10 mM solution in DMSO and as solid sizes for formulation.
- Soluble in DMSO (≈100 mg/mL); may require ultrasonic agitation.
- Storage recommendations include powder at -20°C and prepared solutions at -80°C for extended stability.
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Apexbio Technology LLC PTC209 HBr 1217022-63-3 10mM (in 1mL DMSO)
PTC209 HBr (CAS 1217022-63-3) is the hydrobromide salt form of PTC-209 known as a selective inhibitor of BMI-1 a component of the Polycomb Repressive Complex 1 (PRC1) involved in epigenetic regulation PTC209 HBr inhibits BMI-1 with an IC50 of 0 5 M and suppresses both UTR-mediated reporter activity and endogenous BMI-1 expression in HCT116 colorectal and HT1080 fibrosarcoma cells in a dose-dependent manner independent of cytotoxic effects In vivo treatment of colorectal cancer cells with PTC209 HBr prior to xenotransplantation into mice results in reduced or arrested tumor growth This compound is utilized in studies of cancer stem cell biology and epigenetic modulation in colorectal cancer
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Medchemexpress LLC Apolipoprotein E/APO 5ug
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Recombinant rabbit apolipoprotein E (APOE) is supplied as a lyophilized, affinity- and epitope-tagged protein for biochemical and cell biology research focused on lipid transport, receptor binding, and APOE-related assays. The product is expressed in E. coli and provided with formulation and storage guidance to support reproducible experimental use.
- Recombinant rabbit apolipoprotein E suitable for lipid transport and receptor-binding studies.
- Expressed in E. coli for high-yield production.
- Includes affinity and epitope tags for purification and detection.
- Full-length mature sequence (T20-Q311) representing native protein regions.
- Approximate molecular weight ~55 kDa.
- Purity greater than 90% by reducing SDS-PAGE.
- Lyophilized formulation with stabilizers for room-temperature handling prior to reconstitution.
- Stable storage recommended at -20°C; aliquot and freeze at -20°C or -80°C for extended storage.
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eMolecules 128625-52-5 | PyBop | Combi-Blocks | MFCD00077411 | 520.401 | C18H28F6N6OP2 | 98.000 | F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On1nnc2ccccc12)(N1CCCC1)N1CCCC1 | 1kg | 267211336
PyBop | Combi-Blocks | 128625-52-5 | MFCD00077411 | 520.401 | C18H28F6N6OP2 | 98.000 | F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On1nnc2ccccc12)(N1CCCC1)N1CCCC1 | 1kg | 267211336
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Medchemexpress LLC N-lauryldiethanolamine | 1541-67-9 | MFCD00059002 | 98.0% | 273.45 g/mol | C16H35NO2 | 250 G
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N-Lauryldiethanolamine is an antistatic agent and surfactant-grade reagent used in laboratory research. It exhibits lysosomotropic behavior and has reported inhibitory effects on cell growth at micromolar concentrations; follow the SDS for handling and safety information.
- High purity: 98.0%.
- Molecular weight: 273.45 g/mol.
- Molecular formula: C16H35NO2.
- Antistatic and surfactant properties useful for formulation and dispersion.
- Shows lysosomotropic behavior and cellular growth inhibition at micromolar levels.
- Available in laboratory-scale pack sizes, including 250 g.
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eMolecules 4704-94-3 | TRIMETHYLOLMETHANE | AstaTech | MFCD00192217 | 106.121 | C4H10O3 | 96.000 | OCC(CO)CO | 100g | 801044141
TRIMETHYLOLMETHANE | AstaTech | 4704-94-3 | MFCD00192217 | 106.121 | C4H10O3 | 96.000 | OCC(CO)CO | 100g | 801044141
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Medchemexpress LLC Tranylcypromine hemisulfate | 13492-01-8 | 99.9% | 1 ML
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Tranylcypromine hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. It also acts as a lysine-specific demethylase 1 (LSD1) inhibitor, capable of suppressing lesion growth and ameliorating generalized hyperalgesia in mouse models of induced endometriosis. This compound exhibits antidepressant effects.
- Irreversible, nonselective monoamine oxidase (MAO) inhibitor.
- Lysine-specific demethylase 1 (LSD1) inhibitor.
- Suppresses lesion growth and ameliorates generalized hyperalgesia.
- Neuroprotective against human Aβ(1-42) oligomer-induced toxicity.
- Protects RGCs from glutamate neurotoxicity-induced apoptosis and oxidative stress.
- Promotes mitogen-activated protein kinase 12 (p38 MAPKγ) expression.
- Enhances RGC survival by attenuating NMDA neurotoxicity.
- Increases cell proliferation in brain regions.
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