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Filtered Search Results
Matrix Scientific 2-FLUORO-6-NITROPHENOL-5G
2-Fluoro-6-nitrophenol, 98%; 5g,C6H4FNO3, MFCD00042446, mw 157.10, [1526-17-6]
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Apexbio Technology LLC AZD-5597 924641-59-8 25mg
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AZD-5597 (CAS 924641-59-8) is an imidazole pyrimidine amide compound that acts as a potent inhibitor of cyclin-dependent kinases CDK1 and CDK2 exhibiting an IC50 of 2 nM for both enzymes CDKs are serine/threonine protein kinases involved in regulation of the cell cycle transcription mRNA processing and neuronal differentiation In cellular studies AZD-5597 demonstrates strong antiproliferative activity such as an MIC50 of 0 039 M in LoVo cells The compound displays high aqueous solubility stability under various conditions and does not inhibit CYP enzymes Preclinical pharmacokinetic evaluations reveal favorable properties supporting its utility as a research tool for investigating CDK inhibition and antitumor activity
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Medchemexpress LLC Polyvinyl alcohol | 9002-89-5 | >99% hydrolyzed | 145000 | 5 G
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Polyvinyl alcohol (PVA) with an average molecular weight of 145000 and 99+% hydrolysis. The hydrolysis degree refers to the conversion rate of acetic acid groups to hydroxyl groups in the original polyvinyl acetate. This PVA is obtained by the polymerization of vinyl acetate followed by the removal of acetic acid groups through hydrolysis.
- Can be self-crosslinked to form frozen gels.
- Used as biological excipients.
- Suitable for biochemical assay reagents.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377476 ISD CONTROL SODIUM 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712449 3-METHYLTHIOPROPYL 10G
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Ambeed AMBEED
5000866779 8-BROMO-5-CHLOROQUINOLINE 1GR
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Medchemexpress LLC MTR-106 | 1639357-93-9 | 99.4% | 525.62 | 25 MG
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MTR-106 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor, primarily utilized in cancer research. It effectively induces apoptosis and inhibits cell growth in various cancer models.
- Potent G-quadruplex stabilizer
- RNA polymerase I inhibitor
- Induces apoptosis
- Inhibits cell growth
- Shows antitumor activity in HR-deficient and PARPi-resistant cells
- Suppresses tumor growth in BRCA-deficient and PARPi-resistant xenografts
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Apexbio Technology LLC Olsalazine Sodium 6054-98-4 10mM (in 1mL H2O)
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Olsalazine Sodium (CAS 6054-98-4) is a small-molecule anti-inflammatory agent It is designed to modulate inflammatory pathways thereby reducing the production of local inflammatory mediators Olsalazine Sodium exerts its biological activity primarily through inhibition of prostaglandin and leukotriene synthesis pathways after biotransformation by gut microbiota into 5-aminosalicylic acid (5-ASA) In experimental settings researchers employ olsalazine sodium to investigate disease mechanisms underlying colonic inflammation and to evaluate therapeutic responses in models of intestinal inflammation Currently precise IC50 values for olsalazine sodium have not been reported in the literature Based on these pharmacological properties olsalazine sodium holds research potential in inflammatory bowel disease (IBD) especially ulcerative colitis
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431947 SIRNA MIRNA TRANSFEC 5ML
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Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.5% | 464.96 | 25 MG
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PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). It forms a complex with MMP-12 and also demonstrates potency against MMP-13, MMP-8, MMP-9, and MMP-3.
- Specific inhibitor of MMP-12
- Non-peptidic, non-zinc chelating ligand
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- For research use only
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Medchemexpress LLC TSI-01 | 704878-75-1 | 98.5% | 328.15 | 1 ML
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TSI-01 is a selective inhibitor of LPCAT2, an enzyme involved in the rapid synthesis of pro-inflammatory phospholipid mediators like platelet-activating factor (PAF). It is designed for research use only.
- Selectively inhibits lysophosphatidylcholine acyltransferase 2 (LPCAT2).
- Demonstrates higher potency against human LPCAT2 than LPCAT1.
- Suppresses PAF biosynthesis in mouse peritoneal macrophages.
- Available in various package sizes for research flexibility.
- Provided with detailed documentation for quality assurance.
- Multiple solvent options for reconstitution are available.
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Medchemexpress LLC Odn 2336 (sodium) | DNA, d(G-sp-G-sp-G-G-A-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 1 MG
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ODN 2336 (sodium) is a laboratory chemical provided as a solid. It is stable under recommended storage conditions and is not classified as a hazardous substance or mixture.
- Recommended for laboratory use and substance manufacturing
- Stable when stored under recommended conditions
- Store sealed at 4°C, away from moisture
- Store in solvent at -80°C for up to 6 months or -20°C for up to 1 month
- Ships at room temperature for durations less than two weeks
- Use in well-ventilated areas with appropriate exhaust systems
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Medchemexpress LLC DNA, d(P-thio)(T-C-C-T-G-G-C-G-c7G-G-G-A-A-G-T), sodium salt | 1964506-29-3 | 1 MG
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ODN 20844 sodium is a guanine-modified inhibitory oligonucleotide (INH-ODN) that is more potent than its parent INH-ODN 2088. It impairs TLR7- and TLR9-induced responses by murine immune cells and effectively blocks TLR9-mediated IFN-α release while inhibiting IL-6 secretion in human peripheral blood mononuclear cells.
- Molecular weight of 4872.9 (free acid)
- Off-white to light yellow solid
- Purity of 92.74% by LCMS
- Recommended storage at -20°C, sealed and away from moisture
- In solvent, stable for 6 months at -80°C or 1 month at -20°C
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Medchemexpress LLC 16α,17α-Epoxyprogesterone | 1097-51-4 | 25 G
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16α,17α-Epoxyprogesterone is an important steroid that serves as an intermediate for many hormonal drugs. It can also biotransform into 11α-hydroxy-16α,17α-epoxyprogesterone, another significant intermediate for manufacturing additional compounds. This product is for research use only.
- Acts as an intermediate for numerous hormonal drugs
- Can biotransform into other significant intermediates
- Suitable for research use
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Medchemexpress LLC Icapamespib hydrochloride | 2267287-26-1 | 98.7% | 599.32 g/mol | C19H25Cl2IN6O2S | 5 MG
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Icapamespib hydrochloride is the hydrochloride salt of icapamespib, a selective, orally active inhibitor of epichaperomes assembled by HSP90. Supplied as a high-purity solid for research use, it is intended for biochemical and cellular studies of HSP90-related epichaperome biology and therapeutic modulation.
- Selective inhibitor of epichaperomes assembled by HSP90.
- Intended for biochemical and cellular research applications.
- High purity: 98.7%.
- Molecular weight: 599.32 g/mol.
- Chemical formula: C19H25Cl2IN6O2S.
- White to off-white solid appearance.
- Recommended storage sealed and away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
- Available in 5 mg packaging.
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