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Filtered Search Results
Medchemexpress LLC Terephthalaldehyde | 623-27-8 | MFCD00006949 | 99.9% | 134.13 | C8H6O2 | 250g
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Terephthalaldehyde is a cross-linking agent Terephthalaldehyde can copolymerize with chitosan and acrylic acid to form hydrogels that selectively adsorb anionic dyes Terephthalaldehyde can be used as a drug intermediate to synthesize a series of novel benzothiazole and benzotriazolopyrimidinone heterocyclic compounds[1][2]
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Medchemexpress LLC 3-Benzyl-6-bromo-1H-quinolin-2-one | 924633-09-0 | 98.3% | 314.18 | 100 MG
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3-Benzyl-6-bromo-1H-quinolin-2-one is a drug intermediate used for the synthesis of various active compounds. It is supplied as a white to off-white solid with a purity of 98.33%.
- Purity of 98.33%
- Molecular weight of 314.18
- CAS number 924633-09-0
- Solid appearance
- White to off-white color
- Stable as powder for 3 years at -20°C or 2 years at 4°C
- Stable in solvent for 6 months at -80°C or 1 month at -20°C
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Medchemexpress LLC PR-104A | 680199-06-8 | 99.0% | C14H19BrN4O9S | 1 ML
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PR-104A (SN 27858) is the alcohol metabolite of the phosphate proagent PR-104. It functions as a hypoxia-selective DNA cross-linking and damaging agent and cytotoxin with antitumor activity. It undergoes metabolism under hypoxic conditions via the 1-electron NADPH:cytochrome P450 oxidoreductase and is utilized in research concerning relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL).
- Functions as a hypoxia-selective DNA cross-linking agent
- Acts as a DNA-damaging agent and cytotoxin
- Exhibits antitumor activity
- Undergoes metabolism under hypoxic conditions via 1-electron NADPH:cytochrome P450 oxidoreductase
- Utilized in research concerning relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL)
- For research use only
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Medchemexpress LLC Tris(hydroxymethyl)aminomethane | 77-86-1 | 99.9% | 25 G
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THAM (Tris) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. It is an effective amine compound for pH control in the physiological range.
- Biologically inert amino alcohol
- Low toxicity
- Buffers carbon dioxide and acids
- Effective for pH control in physiological range
- Available as a white to off-white solid
- High purity
- Soluble in water and DMSO
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Medchemexpress LLC N,N'-Carbonyldiimidazole | 530-62-1 | 99.9% | C7H6N4O | 250 G
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N,N'-Carbonyldiimidazole is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. It can be used as a coupling agent and a peptide synthesis reagent.
- Highly reactive carboxylating reagent
- Activates hydroxyl groups to form reactive carbonyl groups
- Functions as a coupling agent
- Used as a peptide synthesis reagent
- Can mediate conjugation of ovalbumin with magnetite nanoparticles for vaccine delivery
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Medchemexpress LLC Guadecitabine sodium | 929904-85-8 | C18H23N9NaO10P | 1 MG
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Guadecitabine sodium is a second-generation DNA methyltransferases (DNMT) inhibitor. It is utilized in research for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).
- Second-generation DNA methyltransferase (DNMT) inhibitor
- Inhibits DNA methylation
- Induces p16 expression
- Effective in reducing DNA methylation and retarding tumor growth
- Better tolerated than 5-Aza-CdR in vivo
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Medchemexpress LLC Sivelestat sodium tetrahydrate | 201677-61-4 | 99.9% | 528.51 | 1 ML
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Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. It has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
- Competitively inhibits human neutrophil elastase.
- Does not inhibit other proteases like trypsin, thrombin, plasmin, plasma kallikrein, pancreas kallikrein, chymotrypsin, and cathepsin G.
- Suppresses lung hemorrhage.
- Ameliorates lung injury after hemorrhagic shock.
- Prevents ischemia-reperfusion injury in the bladder.
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Medchemexpress LLC 2-CTC Resin | 934816-82-7 | 100 G
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2-CTC Resin is a solid-phase synthesis carrier recognized for its versatility in large-scale peptide production. It prevents racemization during initial amino acid incorporation and minimizes diketopiperazine formation. The resin has been used to investigate metabolic disorders in prostate cancer cells and can form cyclic peptides from terminal residues and adenine nucleotides.
- Solid-phase synthesis carrier
- Prevents racemization during amino acid incorporation
- Minimizes diketopiperazine formation
- Versatile for large-scale peptide production
- Forms covalent ester bonds with amino acids for efficient immobilization
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Medchemexpress LLC DNA, d(P-thio)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A), sodium salt | 871479-94-6 | 98.8% | C177H217N60Na18O94P17S17 | 1 MG
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Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits Transforming Growth Factor-beta 2 (TGF-β2). This inhibition makes it a candidate for studying malignant brain tumors and other solid tumors that overexpress TGF-β2, including those found in the skin, pancreas, and colon. It works by interfering with the expression of the TGF-β2 gene.
- Specifically inhibits TGF-β2
- Candidate for studying malignant brain tumors
- Candidate for studying solid tumors overexpressing TGF-β2
- Available as a solid, white to off-white in color
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Apexbio Technology LLC Milnacipran HCl 101152-94-7 10mM (in 1mL DMSO)
Milnacipran hydrochloride (CAS 101152-94-7) is a small molecule classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) It acts by selectively inhibiting the reuptake of both serotonin and norepinephrine in the central nervous system thereby modulating synaptic neurotransmitter levels Milnacipran HCl has been investigated for its ability to influence neurochemical pathways implicated in pain processing and mood regulation It is utilized in biomedical research to study the pathophysiology of fibromyalgia and related disorders involving monoaminergic dysfunction
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Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 5g
Chlorprothixene hydrochloride (CAS 6469-93-8) is a small-molecule antagonist targeting dopamine (D1 D2 D3 D5) and histamine H1 receptors It modulates neurotransmission by blocking these receptors thereby regulating dopaminergic and histaminergic pathways Chlorprothixene hydrochloride exerts its biological activity primarily through receptor antagonism In in vitro studies it demonstrates nanomolar affinity with Ki values of 18 nM (D1) 2 96 nM (D2) 4 56 nM (D3) 9 nM (D5) and 3 75 nM (H1) Additionally it reduces SARS-CoV viral replication (IC50 13 0 18 5 M depending on strain) Based on these pharmacological properties chlorprothixene hydrochloride holds research potential in antipsychotic therapy antiviral investigation and modulation of inflammation in cystic fibrosis models
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Medchemexpress LLC Ecotin E. coli His 100ug | 100ug
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Ecotin a bacterial protein inhibitor regulates serine proteases like trypsin and subtilisin Ecotin s unique surface loop forms a stable complex influencing enzymatic activity Ecotin Protein E coli (His) is the recombinant E coli-derived Ecotin protein expressed by E coli with C-His labeled tag
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Medchemexpress LLC Ditiocarb sodium | 148-18-5 | 99.7% | 5 G
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Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent used in the research of tumors, inflammatory, and immune-related diseases.
- Exhibits antioxidation
- Exhibits chelation
- Exhibits anti-tumor effects
- Exhibits immunomodulation
- Exhibits anti-HIV properties
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Apexbio Technology LLC Cysteamine HCl 156-57-0 5g
Cysteamine HCl (156-57-0) is a small-molecule modulator designed to facilitate cystine export from lysosomes by lowering intracellular cystine levels Cysteamine HCl exerts its biological activity primarily through cleaving cystine disulfide bonds and forming mixed disulfides enabling cystine transport out of lysosomes In in vitro assays Cysteamine HCl demonstrates antioxidant activity with reported IC50 values typically ranging between 30 80 M depending on cell type and assay conditions Based on these pharmacological properties Cysteamine HCl holds research potential in studies of cystinosis lysosomal storage disorders oxidative stress-related models and cystine metabolic pathway analysis
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Medchemexpress LLC DTAC for IPC 99 500g
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DTAC for IPC 99% is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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