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Filtered Search Results
Medchemexpress LLC GM-CSF Mouse HEK29 50ug
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The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages including granulocytes macrophages eosinophils and erythrocytes Structurally GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex GM-CSF Protein Mouse (HEK293 Fc) is the recombinant mouse-derived GM-CSF protein expressed by HEK293 with N-hFc labeled tag
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Medchemexpress LLC Cucurbitacin E | 18444-66-1 | 556.69 | 1 MG
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Cucurbitacin E is a natural compound sourced from Cucurbitaceae plants. It significantly suppresses the activity of the cyclin B1/CDC2 complex and is intended for research use only. This compound exhibits growth inhibition in various cancer cell lines and reduces obesity in mice by targeting the JAK-STAT5 signaling pathway.
- Natural compound from Cucurbitaceae plants.
- Significantly suppresses the activity of the cyclin B1/CDC2 complex.
- Exhibits growth inhibition in various cancer cell lines including human prostate, CNS, breast, colon, HL-60, HSC-T6, HT-1080, HeLa, HepG2, JY, MCF7, and U-937 cells.
- Induces morphological changes in primary colon cancer cells and inhibits tumor growth by arresting the cell cycle in the G2/M phase.
- Reduces obesity and related metabolic dysfunction in mice.
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Medchemexpress LLC Bromo-PEG1-C2-azide | 1144106-65-9 | 99.5% | C4H8BrN3O | 100 MG
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Bromo-PEG1-C2-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Click chemistry reagent with Azide group
- Reacts with Alkyne groups via CuAAc
- Reacts with DBCO or BCN groups via SPAAC
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Medchemexpress LLC G0-C14 | 1510653-27-6 | C106H216N10O10 | 25 MG
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G0-C14 is a cationic lipid-like compound, an alkyl-modified polyamidoamine (PAMAM) dendrimer. It is utilized in the preparation of macrophage-targeted nanoparticles (NPs) for agent and vaccine delivery.
- Strong entrapment of mRNA and pDNA with over 95% encapsulation efficiency.
- Appears as an oil.
- Colorless to light yellow in appearance.
- Purity of 98.0%.
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Medchemexpress LLC Cyromazine | 66215-27-8 | 99.8% | 100 G
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Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine functions by affecting the nervous system of the immature larval stages of certain insects. It has been shown to reduce the number of germ cells by interfering with the Ecdysone signaling pathway and induces renal toxicity, which can be attenuated and restored by green tea extract in rats.
- Insect growth regulator
- Insecticide
- Acaricide
- Affects the nervous system of immature larval stages of certain insects
- Reduces the number of germ cells by interfering with the Ecdysone signaling pathway
- Induces renal toxicity that can be attenuated by green tea extract in rats
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Medchemexpress LLC Ethanone, 2-bromo-1-(2-methoxyphenyl)- | 31949-21-0 | 98.4% | 229.07 | 5 G
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2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, inhibiting MurA in *E. coli* with an IC50 of 0.38 μM. It can be used in antibacterial research for blocking bacterial cell wall synthesis.
- Inhibits MurA in *E. coli* with an IC50 of 0.38 μM.
- Used in antibacterial research.
- Blocks bacterial cell wall synthesis.
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Medchemexpress LLC Copper(II) oxalate | 814-91-5 | MFCD00064789 | 98.0% | 151.56 g/mol | C2CuO4 | 25 G
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Copperoxalate (Copper(II) oxalate, C2CuO4) is an inorganic copper salt supplied as a blue to blue-green solid and used as a reagent in research and synthesis. It provides a stable source of Cu(II) for catalysis, materials preparation, and laboratory studies, and is offered in small laboratory packaging for analytical and preparative work.
- Blue to blue-green solid and stable source of Cu(II).
- Suitable for catalysis and materials synthesis applications.
- Appropriate for laboratory reagent and analytical use.
- Molecular formula C2CuO4; molecular weight 151.56 g/mol.
- Supplied in 25 G packaging; typical purity 98%.
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Medchemexpress LLC Varenicline dihydrochloride | 866823-63-4 | 99.2% | 284.18 g/mol | C13H15Cl2N3 | 50 MG
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Varenicline dihydrochloride is a small-molecule partial agonist of neuronal nicotinic acetylcholine receptors, used as a research reagent to study α4β2, α6β2, and α7 receptor pharmacology and mechanisms of nicotine dependence. The dihydrochloride salt improves aqueous solubility for in vitro assays and analytical workflows.
- Potent partial agonist of α4β2 nicotinic receptors.
- Also active at α6β2 and α7 receptor subtypes.
- Suitable for in vitro pharmacology and signaling studies.
- High reported purity appropriate for research use.
- Dihydrochloride salt enhances solubility in aqueous media.
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Apexbio Technology LLC Verapamil HCl 152-11-4 5g
Verapamil HCl (CAS 152-11-4) is a small molecule belonging to the phenylalkylamine class characterized by selective inhibition of L-type calcium channels By blocking calcium influx through voltage-dependent calcium channels verapamil modulates intracellular calcium signaling affecting smooth muscle contraction cardiac electrophysiology and neurotransmitter release It is frequently utilized in research to investigate calcium channel-related physiological processes cardiovascular function and cellular signaling mechanisms
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Medchemexpress LLC Parecoxib (Sodium) | 198470-85-8 | 99.6% | 392.40 | 10 MM 1 ML
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Parecoxib Sodium is a highly selective, orally active, and blood-brain barrier-permeable COX-2 inhibitor, functioning as a prodrug of Valdecoxib. It is a nonsteroidal anti-inflammatory agent (NSAID) that inhibits prostaglandin synthesis. It is used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions like osteoarthritis and rheumatoid arthritis.
- Target: COX-2
- Inhibits cell proliferation of GBM cells in a dose-dependent manner
- Decreases migratory ability of U343 cells
- Chronic administration exerts anxiolytic-like and memory-enhancing effects in mice
- Modulates synaptophysin expression in mice
- Appearance: Solid
- Color: White to off-white
- Shipping at room temperature in continental US
- Storage at 4°C, sealed, away from moisture
- In solvent storage at -80°C for 6 months or -20°C for 1 month
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Alkali Scientific Timentin [Ticarcillin Disodium Salt/Potassium Clavulanate Mixture 15:1 Ratio], 100 G
Timentin (100g) combines Ticarcillin Disodium Salt and Potassium Clavulanate in a 15:1 ratio to offer broad-spectrum antibacterial activity. The Ticarcillin component disrupts bacterial cell wall synthesis, while Potassium Clavulanate prevents bacterial resistance by inhibiting beta-lactamase enzymes. This 100g size is ideal for preparing larger volumes of solution for high-throughput testing or clinical treatments. Timentin is highly effective against Gram-negative and Gram-positive organisms, especially those resistant to other antibiotics. It is commonly used in treating complex infections such as sepsis, pneumonia, and intra-abdominal infections in hospital settings.
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Medchemexpress LLC Bis(pinacolato)diborane | 73183-34-3 | 99.97% | C12H24B2O4 | 100 G
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Bis(pinacolato)diborane is an organoboron reagent. It functions as a source of the [Bpin] moiety, which exhibits a pronounced nucleophilic character. This makes it valuable in the synthesis of various organoboranes, including organoboron compounds and arylboronates. Additionally, Bis(pinacolato)diborane is known to react with p-benzyne, leading to the production of tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group.
- Organoboron reagent
- Source of nucleophilic [Bpin] moiety
- Used in the synthesis of various organoboranes, including organoboron compounds and arylboronates
- Reacts with p-benzyne to produce tetraborylated products
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eMolecules 116435-77-9 | 2-Amino-3-bromophenol | Combi-Blocks | MFCD08445676 | 188.024 | C6H6BrNO | 98.000 | Nc1c(O)cccc1Br | 25g | 290689683
2-Amino-3-bromophenol | Combi-Blocks | 116435-77-9 | MFCD08445676 | 188.024 | C6H6BrNO | 98.000 | Nc1c(O)cccc1Br | 25g | 290689683
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eMolecules 1143516-05-5 | AEEA-AEEA | Ambeed | MFCD13184942 | 308.331 | C12H24N2O7 | 98.000 | NCCOCCOCC(=O)NCCOCCOCC(O)=O | 100g | 633658012
AEEA-AEEA | Ambeed | 1143516-05-5 | MFCD13184942 | 308.331 | C12H24N2O7 | 98.000 | NCCOCCOCC(=O)NCCOCCOCC(O)=O | 100g | 633658012
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Apexbio Technology LLC Fenspiride HCl 5053-08-7 25g
Fenspiride hydrochloride (CAS 5053-08-7) is a small molecule antagonist of -adrenergic and histamine H1 receptors By inhibiting these signaling pathways Fenspiride HCl modulates bronchial smooth muscle tone and reduces inflammatory processes mediated by histamine and adrenergic activity This compound is utilized in biomedical research to investigate mechanisms of airway hyperreactivity neurogenic inflammation and the pharmacological modulation of respiratory tract disorders related to histaminergic and adrenergic signaling
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