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Filtered Search Results
Apexbio Technology LLC (+,-)-Octopamine HCl 770-05-8 5g
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( -)-Octopamine HCl (CAS 770-05-8) is a biogenic monoamine structurally analogous to noradrenaline In invertebrates it functions as a neurohormone neuromodulator and neurotransmitter by interacting with specific octopamine receptors to regulate physiological and behavioral processes including metabolism locomotion and learning The compound is widely utilized in neurobiological research to investigate aminergic signaling pathways synaptic transmission and the functional roles of monoamines in invertebrate nervous systems Its use facilitates studies on neurotransmitter mechanisms distinct from those predominant in vertebrates
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Apexbio Technology LLC Mouse CD8+ T Cell Isolation Kit (Negative Selection) 100assays(for 1×10⁹ cells)
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Mouse CD8plus T Cell Isolation Kit Negative Selection is a reagent kit designed for the isolation of untouched CD8 T cells It employs a negative immunomagnetic selection mechanism where non-CD8 T cells are labeled with biotin-conjugated antibodies and subsequently removed using streptavidin-conjugated magnetic beads The kit is optimized for use with murine splenic or lymph node single-cell suspensions The isolated CD8 T cell population typically achieves a purity of over 95% Based on these properties Mouse CD8plus T Cell Isolation Kit Negative Selection is suitable for downstream applications including flow cytometry functional assays or adoptive transfer experiments
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Apexbio Technology LLC Sodium Monofluorophosphate 10163-15-2 10mM (in 1mL H20)
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Sodium Monofluorophosphate is a small-molecule inhibitor targeting enzymes including pyruvate kinase alkaline phosphatase and phosphorylase phosphatase It is designed to competitively and irreversibly inhibit these enzymes thereby modulating enzyme-mediated phosphorylation processes and impacting glycogen metabolism pathways Sodium Monofluorophosphate exerts its biological activity primarily through competitive inhibition of pyruvate kinase and alkaline phosphatase by interfering with endogenous phosphate substrates and irreversible inhibition of phosphorylase phosphatase Based on these pharmacological properties Sodium Monofluorophosphate holds research potential in the study of enzymatic mechanisms involving phosphate-transfer reactions and in investigations of metabolic regulations dependent on pyruvate kinase alkaline phosphatase and phosphorylase phosphatase pathways
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Apexbio Technology LLC Butenafine HCl 101827-46-7 5g
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Butenafine HCl (CAS 101827-46-7) is a small-molecule inhibitor targeting squalene epoxidase It is designed to inhibit this enzyme thereby disrupting fungal sterol biosynthesis Butenafine HCl exerts its biological activity primarily through inhibition of squalene epoxidase leading to impaired ergosterol synthesis and accumulation of squalene which disrupts fungal cell membrane integrity and results in cell death In biochemical studies Butenafine HCl demonstrates inhibitory activity with reported IC50 values ranging from approximately 0 03 M to 0 1 M depending on fungal species and experimental conditions Based on these pharmacological properties Butenafine HCl holds research potential in biomedical antifungal studies including investigations into fungal physiology antifungal efficacy and drug resistance mechanisms
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Apexbio Technology LLC Eletriptan HBr 177834-92-3 10mM (in 1mL DMSO)
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Eletriptan hydrobromide (CAS 177834-92-3) is an orally bioavailable small molecule that acts as a selective agonist for the 5-hydroxytryptamine (serotonin) 5-HT1B and 5-HT1D receptors By activating these receptor subtypes eletriptan hydrobromide modulates cranial blood vessel tone and neuronal signaling implicated in migraine pathophysiology This compound is commonly utilized in preclinical and clinical research to investigate serotonergic modulation of neurovascular function and to explore therapeutic mechanisms relevant to migraine and related neurovascular disorders
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Medchemexpress LLC Trimethylacetohydrazideammonium chloride | 123-46-6 | MFCD00012009 | 99.8% | 167.64 g/mol | C5H14ClN3O | 100 G
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Girard's reagent T is a quaternary hydrazide salt used to derivatize carbonyl compounds (aldehydes and ketones) into stable hydrazones for chromatographic and spectrometric analysis. It is a water-soluble solid commonly used in analytical chemistry and organic synthesis for selective enrichment, detection, and quantification of carbonyl-containing molecules.
- Derivatizes aldehydes and ketones to form stable hydrazones.
- Water-soluble solid suitable for chromatographic and spectrometric analysis.
- High purity for reliable analytical results.
- Useful for selective enrichment and detection of carbonyl-containing compounds.
- Available in multiple pack sizes for laboratory and bulk use.
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Medchemexpress LLC Sodium glycolate | 2836-32-0 | MFCD00065358 | 98.0% | 98.03 g/mol | C2H3NaO3 | 25 G
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Sodium glycolate is the sodium salt of glycolic (hydroxyacetic) acid supplied as a white to off-white solid with 98.0% purity. It is used as a metal chelating agent and as a reagent in biochemical assays and buffer formulations.
- Used as a metal chelating agent in biochemical applications.
- Purity: 98.0%.
- CAS number: 2836-32-0.
- Chemical formula: C2H3NaO3.
- Molecular weight: 98.03 g/mol.
- Available in 10 g, 25 g, 50 g, and larger package sizes.
- Documents available: SDS, COA, data sheet.
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Medchemexpress LLC BRAF inhibitor | 918505-61-0 | MFCD16659048 | 99.0% | 456.47 | C22H18F2N4O3S | 1 ML
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BRAF inhibitor (Compound P-0850) is a small-molecule B-Raf kinase inhibitor with reported anti-tumor activity. It is supplied for research use as a solid and as a pre-dosed 10 mM solution in DMSO; formulation protocols, solubility data, and storage recommendations are provided for both in vitro and in vivo applications.
- High purity (~99%).
- Available as 10 mM solution in DMSO or as solid in multiple pack sizes.
- Soluble in DMSO; in vitro solubility reported up to 50 mg/mL (≈109.5 mM).
- In vivo formulation protocols provided for common vehicles (PEG300, Tween-80, SBE-β-CD, corn oil).
- Storage recommendations given for powder and solution to preserve stability.
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Medchemexpress LLC Bomedemstat hydrochloride | 99.9% | 556.07 g/mol | C28H35ClFN7O2 | 5 MG
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Bomedemstat hydrochloride is the hydrochloride salt of bomedemstat, an orally active, irreversible lysine-specific demethylase 1 (LSD1) inhibitor used in preclinical research to modulate histone methylation and evaluate antineoplastic activity. Supplied as a high-purity solid for research use.
- Irreversible LSD1 inhibitor.
- Hydrochloride salt for improved solubility.
- High purity (≈99.9%).
- Modulates H3K4 and H3K9 methylation.
- Suitable for in vitro and preclinical studies.
- Available as solid and as a 10 mM DMSO solution.
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Medchemexpress LLC Dasotraline hydrochloride | 675126-08-6 | >98.0% | 328.66 g/mol | C16H16Cl3N | 5 MG
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Dasotraline hydrochloride is the hydrochloride salt of dasotraline (SEP-225289), a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters. It is provided for research use in biochemical and pharmacological studies of monoamine transporter inhibition.
- Triple reuptake inhibitor activity at DAT, NET, and SERT with reported low-nanomolar IC50 values.
- High purity suitable for research and analytical applications.
- Available in small mass quantities for preparation of stock solutions.
- Analytical data (HPLC, NMR) provided in accompanying documentation.
- Suitable as a reference compound in transporter and pharmacokinetic assays.
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Medchemexpress LLC Cddo-ea | 932730-51-3 | 99.8% | 1 ML
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CDDO-EA (CDDO ethyl amide) is a synthetic triterpenoid that activates the NF-E2-related factor 2/antioxidant response element (Nrf2/ARE) signaling pathway. It is used in research to modulate oxidative stress, inflammation, and apoptosis, and is supplied as a solid or as a 10 mM solution in DMSO for cell-based assays.
- Activates Nrf2/ARE signaling and modulates oxidative stress.
- Available as a solid or a 10 mM solution in DMSO.
- High purity suitable for research use.
- Molecular weight 518.73 g/mol; formula C33H46N2O3.
- Commonly used in in vitro studies of inflammation and apoptosis.
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Chemscene ChemScene | 3-Bromo-2-nitrophenol | 10G | CS-0042077 | 0.98 | 76361-99-4| MFCD08445675 | 218.006
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ChemScene | 3-Bromo-2-nitrophenol | 10G | CS-0042077 | 0.98 | 76361-99-4| MFCD08445675 | 218.006
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eMolecules Chem-Impex Lawesson's reagent 25g 112766576 26927 98.000 19172-47-5 MFCD00005171 404.450 C14H14O2P2S4
Chem-Impex Lawesson's reagent 25g 112766576 26927 98.000 19172-47-5 MFCD00005171 404.450 C14H14O2P2S4
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3-Bromo-2-hydroxybenzonitrile, 97%, Thermo Scientific™
CAS: 13073-28-4 Molecular Formula: C7H4BrNO Molecular Weight (g/mol): 198.02 MDL Number: MFCD11042854 InChI Key: BUWXNBPLRLEXOZ-UHFFFAOYSA-N Synonym: 2-bromo-6-cyanophenol,benzonitrile,3-bromo-2-hydroxy,acmc-1c4pd,2-hydroxy-3-bromobenzonitrile,3-bromo-2-hydroxy-benzonitrile,benzonitrile, 3-bromo-2-hydroxy,3-bromo-2-hydroxybenznitrile,3-bromo-2-hydroxybenzonitrile,-8-hydroxy-2-dipropylamino tetralin hydrobromide PubChem CID: 12468680 IUPAC Name: 3-bromo-2-hydroxybenzonitrile SMILES: OC1=C(C=CC=C1Br)C#N
| PubChem CID | 12468680 |
|---|---|
| CAS | 13073-28-4 |
| Molecular Weight (g/mol) | 198.02 |
| MDL Number | MFCD11042854 |
| SMILES | OC1=C(C=CC=C1Br)C#N |
| Synonym | 2-bromo-6-cyanophenol,benzonitrile,3-bromo-2-hydroxy,acmc-1c4pd,2-hydroxy-3-bromobenzonitrile,3-bromo-2-hydroxy-benzonitrile,benzonitrile, 3-bromo-2-hydroxy,3-bromo-2-hydroxybenznitrile,3-bromo-2-hydroxybenzonitrile,-8-hydroxy-2-dipropylamino tetralin hydrobromide |
| IUPAC Name | 3-bromo-2-hydroxybenzonitrile |
| InChI Key | BUWXNBPLRLEXOZ-UHFFFAOYSA-N |
| Molecular Formula | C7H4BrNO |
2-Fluoro-6-hydroxybenzeneboronic acid pinacol ester, 96%, Thermo Scientific™
CAS: 1534369-41-9 Molecular Formula: C12H16BFO3 Molecular Weight (g/mol): 238.07 MDL Number: MFCD16994234 InChI Key: GXNDNRWVVOKEBG-UHFFFAOYSA-N Synonym: 2-fluoro-6-hydroxybenzeneboronic acid pinacol ester,3-fluoro-2-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl phenol,2-fluoro-6-hydroxyphenylboronic acid pinacol ester PubChem CID: 72219403 IUPAC Name: 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol SMILES: CC1(C)OB(OC1(C)C)C1=C(O)C=CC=C1F
| PubChem CID | 72219403 |
|---|---|
| CAS | 1534369-41-9 |
| Molecular Weight (g/mol) | 238.07 |
| MDL Number | MFCD16994234 |
| SMILES | CC1(C)OB(OC1(C)C)C1=C(O)C=CC=C1F |
| Synonym | 2-fluoro-6-hydroxybenzeneboronic acid pinacol ester,3-fluoro-2-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl phenol,2-fluoro-6-hydroxyphenylboronic acid pinacol ester |
| IUPAC Name | 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol |
| InChI Key | GXNDNRWVVOKEBG-UHFFFAOYSA-N |
| Molecular Formula | C12H16BFO3 |