Halophenols

Organic compounds derived from phenols that contain a halogen atom (bromine, chlorine, fluorine, iodine).

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6,736 – 6,750 of 12,498 results

6,736

Apexbio Technology LLC β-Interleukin I (163-171), human 106021-96-9 10mg

beta-Interleukin I 163-171 human is a peptide fragment derived from human interleukin-1 (IL-1 ) It is utilized to investigate immune signaling pathways particularly those involved in inflammatory responses and T cell activation beta-Interleukin I 163-171 human exerts its biological activity by participating in the modulation of inflammatory signaling cascades relevant to immune system regulation Based on these pharmacological properties beta-Interleukin I 163-171 human holds research potential in the study of immune activation inflammation and associated signaling mechanisms in biomedical research

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6,737

Apexbio Technology LLC Mouse CD8+ T Cell Isolation Kit (Negative Selection) 100assays(for 1×10⁹ cells)

Mouse CD8plus T Cell Isolation Kit Negative Selection is a reagent kit designed for the isolation of untouched CD8 T cells It employs a negative immunomagnetic selection mechanism where non-CD8 T cells are labeled with biotin-conjugated antibodies and subsequently removed using streptavidin-conjugated magnetic beads The kit is optimized for use with murine splenic or lymph node single-cell suspensions The isolated CD8 T cell population typically achieves a purity of over 95% Based on these properties Mouse CD8plus T Cell Isolation Kit Negative Selection is suitable for downstream applications including flow cytometry functional assays or adoptive transfer experiments

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6,738

Apexbio Technology LLC Tetrahydro-β-carboline 16502-01-5 1g

Tetrahydro- -carboline (CAS 16502-01-5) is a -carboline alkaloid derivative characterized by a tetrahydroindole fused to a pyridine ring This compound modulates neurotransmitter dynamics in the central nervous system by interacting with specific receptors and enzymes thereby influencing neurotransmitter release and metabolism Tetrahydro- -carboline has been utilized in studies on drug dependence neuroprotection and cognitive function within neuropharmacology Its molecular framework supports applications in the development of lead compounds and the investigation of neurobiological pathways involved in central nervous system disorders

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6,739

Apexbio Technology LLC Dorzolamide HCl 130693-82-2 10mM (in 1mL H2O)

Dorzolamide hydrochloride (CAS 130693-82-2) is a synthetic small molecule that selectively inhibits carbonic anhydrase an enzyme involved in the reversible hydration of carbon dioxide By blocking this enzyme s activity Dorzolamide HCl reduces the production of aqueous humor which influences intraocular pressure This mechanism underpins its utility in studies investigating ocular physiology glaucoma pathogenesis and the pharmacological modulation of carbonic anhydrase Dorzolamide HCl serves as a valuable tool for elucidating carbonic anhydrase-related pathways in preclinical and biochemical research contexts

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6,740

Apexbio Technology LLC Ziprasidone HCl 122883-93-6 10mM (in 1mL DMSO)

Ziprasidone hydrochloride (CAS 122883-93-6) is a small molecule classified as an atypical antipsychotic that exerts its pharmacological effects primarily through antagonism of serotonin 5-HT2A and dopamine D2 receptors It demonstrates high binding affinity for the 5-HT2A receptor with a 5-HT2A/D2 affinity ratio greater than those observed in other atypical antipsychotics (pKi for 5-HT2A 9 38) This dual antagonistic activity modulates neurotransmitter pathways implicated in neuropsychiatric disorders Ziprasidone HCl is frequently utilized in research to investigate serotonergic and dopaminergic mechanisms relevant to schizophrenia mood disorders and behavioral pharmacology

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6,741

Apexbio Technology LLC ODN 1826 sodium 1mg

ODN 1826 sodium is a synthetic oligodeoxynucleotide agonist targeting Toll-like receptor 9 (TLR9) It is designed to activate TLR9-mediated immune responses thereby modulating both innate and adaptive immunity ODN 1826 sodium exerts its biological activity primarily through direct interaction with TLR9 which is expressed in intracellular compartments of immune cells such as dendritic cells macrophages and B lymphocytes Upon binding it triggers downstream signaling cascades leading to the secretion of cytokines including type I interferons and interleukin-12 (IL-12) promoting the polarization of T-helper type 1 (Th1) immune responses Based on these pharmacological properties ODN 1826 sodium holds research potential in studies of immune activation mechanisms tumor immunology infectious disease modeling and vaccine adjuvant development

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6,742

Apexbio Technology LLC Imidapril HCl 89396-94-1 10mM (in 1mL DMSO)

Imidapril hydrochloride (CAS 89396-94-1) is a synthetic angiotensin-converting enzyme (ACE) inhibitor that interrupts the renin-angiotensin-aldosterone system by preventing the conversion of angiotensin I to angiotensin II This inhibition leads to vasodilation and a reduction in blood pressure and has been associated with improvements in cardiac function Imidapril HCl is extensively utilized in biomedical research to investigate the molecular mechanisms underlying hypertension and chronic heart failure as well as to evaluate ACE inhibition in various experimental models

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6,743

Apexbio Technology LLC α-Casein (90-95) TFA 1mg

alpha-Casein 90-95 TFA is a peptide fragment derived from bovine -casein It is used as a defined substrate or competitor peptide to investigate protein-protein interactions receptor binding specificity and enzymatic activity assays alpha-Casein 90-95 TFA exerts its biological activity primarily by serving as a tool in studies of signal transduction pathways mediated by protein kinases or regulatory enzymes Based on these properties alpha-Casein 90-95 TFA holds research potential in biochemical and biomedical research including studies of protein interactions immunological assays for antigen recognition and antibody affinity and pharmacological research involving receptor-ligand interactions and peptidomimetic screening

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6,744

Apexbio Technology LLC Conivaptan HCl 168626-94-6 10mM (in 1mL DMSO)

Conivaptan Hydrochloride (CAS 168626-94-6) is a non-peptide antagonist of the antidiuretic hormone vasopressin It selectively inhibits vasopressin V1A and V2 receptors thereby blocking vasopressin-mediated water reabsorption in renal collecting ducts This action promotes aquaresis without affecting sodium or potassium excretion Conivaptan Hydrochloride is utilized in biomedical research to investigate pathways involved in fluid balance sodium homeostasis and cardiovascular dysfunction including models of congestive heart failure and disorders of hyponatremia

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6,745

Apexbio Technology LLC Ticarcillin sodium 29457-07-6 10mM (in 1mL DMSO)

Ticarcillin sodium (29457-07-6) is a semisynthetic beta-lactam antibiotic targeting bacterial transpeptidase enzymes (penicillin-binding proteins) It is designed to inhibit bacterial cell wall synthesis thereby compromising cell wall integrity Ticarcillin sodium exerts its biological activity primarily through irreversible inhibition of transpeptidase enzymes In antimicrobial susceptibility assays Ticarcillin sodium demonstrates bactericidal activity with minimum inhibitory concentration (MIC) values typically ranging from 2 g/mL to above 128 g/mL depending on the bacterial species tested Based on these pharmacological properties Ticarcillin sodium holds research potential in selective antibacterial applications including the isolation or screening of bacterial strains and comparative evaluation of bacterial resistance or sensitivity profiles

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6,746

Apexbio Technology LLC Butenafine HCl 101827-46-7 5g

Butenafine HCl (CAS 101827-46-7) is a small-molecule inhibitor targeting squalene epoxidase It is designed to inhibit this enzyme thereby disrupting fungal sterol biosynthesis Butenafine HCl exerts its biological activity primarily through inhibition of squalene epoxidase leading to impaired ergosterol synthesis and accumulation of squalene which disrupts fungal cell membrane integrity and results in cell death In biochemical studies Butenafine HCl demonstrates inhibitory activity with reported IC50 values ranging from approximately 0 03 M to 0 1 M depending on fungal species and experimental conditions Based on these pharmacological properties Butenafine HCl holds research potential in biomedical antifungal studies including investigations into fungal physiology antifungal efficacy and drug resistance mechanisms

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6,747

Apexbio Technology LLC WWL 70 947669-91-2 2000mg

WWL 70 (CAS 947669-91-2) is a small molecule inhibitor targeting / hydrolase domain-containing protein 6 (ABHD6) a serine hydrolase implicated in lipid metabolism Developed as an O-arylated derivative of carbamate 18 WWL 70 demonstrates approximately five-fold enhanced potency exhibiting an IC50 of 70 nM for ABHD6 inhibition Activity-based protein profiling and proteomic studies indicate that WWL 70 selectively inhibits ABHD6 over a panel of 27 serine hydrolases with minimal activity against ABHD10 at concentrations up to 100 M WWL 70 serves as a valuable chemical probe for elucidating ABHD6 function and investigating lipid signaling pathways in neurological research

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6,748

Apexbio Technology LLC Anagrelide HCl 58579-51-4 10mM (in 1mL DMSO)

Anagrelide hydrochloride (CAS 58579-51-4) is a selective thrombocytopenic agent approved for the treatment of essential thrombocythemia Its primary mechanism involves inhibiting the maturation of megakaryocytes thereby reducing platelet production without significantly affecting leukocytes or erythrocytes Orally administered anagrelide demonstrates platelet-lowering effects at doses as low as 0 5 mg In preclinical studies anagrelide exhibits positive inotropic and vasodilatory properties with additional implications for use in other myeloproliferative disorders such as polycythemia vera and chronic myeloid leukemia Its application extends to research on thrombopoiesis and related hematological pathologies

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6,749

Apexbio Technology LLC Epinastine HCl 108929-04-0 10mM (in 1mL DMSO)

Epinastine hydrochloride (CAS 108929-04-0) is a small molecule antagonist of the histamine H1 receptor and a mast cell stabilizer By inhibiting H1 receptor-mediated signaling and preventing the degranulation of mast cells epinastine suppresses the release of pro-inflammatory mediators such as histamine It is commonly applied in ophthalmic research models to investigate mechanisms underlying allergic conjunctival inflammation and to evaluate antiallergic therapies Epinastine hydrochloride is used to study the modulation of allergic responses at the cellular and molecular levels particularly within ocular tissues

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6,750

Apexbio Technology LLC 2,4,6-Triiodophenol 609-23-4 10mg

2 4 6-Triiodophenol (CAS 609-23-4) is a small molecule inhibitor known to block the biosynthetic pathway of leukotriene B4 (LTB4) thereby modulating the production of pro-inflammatory mediators By targeting LTB4 synthesis it serves as a valuable tool for studying inflammatory processes and related signaling mechanisms Additionally this compound has been reported to induce apoptosis in murine blastocyst-stage cells making it relevant for investigations into early embryonic development embryotoxicity and the regulation of apoptotic pathways

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Halophenols

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