Halophenols
Medchemexpress LLC Pregnan-20-one, 3,17,21-trihydroxy-, (3α,5β)- | 68-60-0 | MFCD00069490 | 98.2% | 350.49 g·mol⁻¹ | C21H34O4 | 5 MG
Tetrahydro-11-deoxycortisol is an endogenous urinary steroid metabolite supplied as a research reference standard for studies of 11β-hydroxylase deficiency and steroid metabolism. It is provided as a white to off-white solid suitable for analytical and biochemical applications.
- High purity (>98.2% by HPLC).
- Suitable as a reference standard for steroid metabolism and diagnostic research.
- Solid form for accurate weighing and analytical preparation.
- Molecular formula C21H34O4; molecular weight 350.49 g·mol⁻¹.
- Available in small-quantity vials for method development and validation.
Medchemexpress LLC (S)-2-Aminopropanamide (hydrochloride) | 33208-99-0 | ≥97.0% | C3H9ClN2O | 50 G
This chemical is (S)-2-Aminopropanamide (hydrochloride), identified by CAS Number 33208-99-0. It has a molecular formula of C3H9ClN2O and a purity of ≥97.0%. It is a white to off-white solid.
- CAS Number: 33208-99-0
- Purity: ≥97.0%
- Molecular formula: C3H9ClN2O
- Molecular weight: 124.57
- Appearance: White to off-white solid
- Storage conditions for powder: -20°C for 3 years; 4°C for 2 years
- Storage conditions in solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC 3-Benzyl-6-bromo-1H-quinolin-2-one | 924633-09-0 | 98.3% | 314.18 | 100 MG
3-Benzyl-6-bromo-1H-quinolin-2-one is a drug intermediate used for the synthesis of various active compounds. It is supplied as a white to off-white solid with a purity of 98.33%.
- Purity of 98.33%
- Molecular weight of 314.18
- CAS number 924633-09-0
- Solid appearance
- White to off-white color
- Stable as powder for 3 years at -20°C or 2 years at 4°C
- Stable in solvent for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC Broussonin E | 90902-21-9 | 1 ML
Broussonin E is a phenolic compound exhibiting anti-inflammatory activity. It suppresses inflammation by modulating the activation state of macrophages through inhibiting the ERK and p38 MAPK pathways, while enhancing the JAK2-STAT3 signaling pathway. This compound can be utilized for research related to inflammation-related diseases, such as atherosclerosis.
- Inhibits LPS (lipopolysaccharides)-stimulated phosphorylation of ERK and p38 MAPK at 20 μM for 3 hours.
- Activates janus kinase (JAK) 2 and signal transducer and activator of transcription (STAT) 3.
- Suppresses LPS-induced pro-inflammatory production in RAW264.7 cells (0-20 μM, 3 h), including TNF-α, IL-1β, IL-6, COX-2, and iNOS.
- Enhances the expression of anti-inflammatory mediators such as IL-10, CD206, and arginase-1 (Arg-1) in LPS-stimulated RAW264.7 cells.
Medchemexpress LLC 2'-bromo-2'-deoxyuridine | 4753-02-0 | MFCD06658226 | 96.9% | 307.10 g/mol | C9H11BrN2O5 | 5 MG
2'-Bromo-2'-deoxyuridine is a brominated deoxyuridine nucleoside analog supplied for research use. It is provided as a white to off-white solid and is commonly used as a thymidine analog for DNA incorporation, cell proliferation assays, and other biochemical studies.
- White to off-white solid appearance.
- Molecular formula C9H11BrN2O5; molecular weight 307.10 g/mol.
- CAS number 4753-02-0.
- Purity 96.9% (HPLC).
- Storage: powder at -20°C for long-term stability.
- Intended for research use only.
Medchemexpress LLC 2'-bromo-2'-deoxyuridine | 4753-02-0 | MFCD06658226 | 96.9% | 307.10 g/mol | C9H11BrN2O5 | 100 MG
2'-Bromo-2'-deoxyuridine is a brominated deoxyuridine nucleoside supplied for research use. It serves as a nucleoside analog for biochemical and molecular biology studies where modified nucleosides are required.
- Brominated deoxyuridine nucleoside for incorporation in nucleic acid studies.
- Molecular formula C9H11BrN2O5; molecular weight 307.10 g/mol.
- Purity 96.9% by HPLC (certificate of analysis).
- Available as a powder; storage recommended at -20°C for long-term stability.
- CAS number 4753-02-0 for chemical identification.
- Supplied in a 100 mg quantity suitable for lab-scale research.
Apexbio Technology LLC Tranylcypromine hydrochloride 1986-47-6 10mM (in 1mL DMSO)
Tranylcypromine hydrochloride (CAS 1986-47-6) is a small molecule inhibitor that irreversibly targets monoamine oxidase (MAO) isoforms A and B demonstrating mechanism-based inhibition with Ki values of 101 9 M for MAO A and 16 M for MAO B and corresponding IC50 values of 2 3 M and 0 95 M Additionally tranylcypromine acts as a time-dependent irreversible inhibitor of lysine-specific demethylase 1 (LSD1) an amine oxidase homolog with structural similarities to MAOs exhibiting a Ki of 242 M and an IC50 of 20 7 M This compound is widely utilized in studies investigating MAO and LSD1 enzymatic functions epigenetic regulation and monoamine metabolism
Apexbio Technology LLC AZD-3463 1356962-20-3 100mg
AZD-3463 (CAS 1356962-20-3) is an orally bioavailable small molecule inhibitor targeting anaplastic lymphoma kinase (ALK) and insulin-like growth factor 1 receptor (IGF1R) exhibiting a Ki of 0 75 nM ALK expression is predominantly neuronal and is upregulated in neuroblastoma where its activation promotes cell survival and proliferation In vitro AZD-3463 suppresses proliferation of neuroblastoma cell lines with wild-type or mutant ALK by inhibiting the ALK-mediated PI3K/AKT/mTOR signaling pathway leading to apoptosis and autophagy induction AZD-3463 also enhances the cytotoxicity of chemotherapeutic agents such as doxorubicin and temozolomide In vivo it has demonstrated efficacy in reducing neuroblastoma growth in xenograft mouse models
Medchemexpress LLC N-methylnicotinamide | 114-33-0 | MFCD00006384 | 99.6% | 136.15 g/mol | C7H8N2O | 5G
N-Methylnicotinamide is an endogenous metabolite supplied as a high-purity solid for research use. It is provided as an analytical standard suitable for in vitro and in vivo studies, with recommended storage and formulation guidance for laboratory applications.
- High purity: 99.6%
- CAS number: 114-33-0
- Molecular weight: 136.15 g/mol; formula: C7H8N2O
- Appearance: white to off-white solid
- Solubility: DMSO 200 mg/mL (may require sonication)
- Recommended storage: 4°C, protect from light; in solvent -80°C (6 months), -20°C (1 month)
- Pack sizes: includes 5 G; larger quantities available upon request