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Filtered Search Results
Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.6% | C28H32N2O7 | 25 MG
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Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing lung damage and improving lung function in chronic obstructive pulmonary disorder (COPD). It also shows promise in cardiovascular disease research, normalizing and reversing cardiac remodeling in a myocardial infarction rat model of heart failure.
- Inhibits NF-κB activity in a β-arrestin2-dependent manner.
- Helps prevent lung damage.
- Improves lung function in chronic obstructive pulmonary disorder (COPD).
- Used in cardiovascular disease research.
- Normalizes and reverses cardiac remodeling in myocardial infarction rat models.
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eMolecules BENZYL PROPIOLATE | 14447-01-9 | MFCD11976128 | 1g
AstaTech | BENZYL PROPIOLATE | 1g | 290661382 | 20949 | 95.000 | 14447-01-9 | MFCD11976128 | 160.172 | C10H8O2
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Medchemexpress LLC Pirepemat fumarate | 2251806-70-7 | 98.3% | C15H17F2NO5 | 10MG
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Pirepemat fumarate is the fumarate salt of pirepemat (IRL752), a cortical-preferring catecholamine- and cognition-promoting research compound investigated for reducing falls and improving cognitive and motor function in Parkinson's disease. The compound is provided as a stable fumarate salt and is used in preclinical and clinical research to modulate cortical neurotransmitter signaling.
- Fumarate salt for improved chemical stability.
- Cortical-preferring catecholamine and cognition-promoting activity.
- Investigated for reduction of falls and improvement of balance in Parkinson's disease.
- Shown to enhance cortical dopamine, acetylcholine, and norepinephrine transmission.
- Supplied in solid and DMSO solution formats for flexible dosing and formulation.
- High purity suitable for research applications.
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Medchemexpress LLC Sumanirole maleate (U-95666E; PNU-95666E) | 179386-44-8 | 99.8% | C15H17N3O5 | 100 MG
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Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. It plays an important role in the research of Parkinson's disease and restless leg syndrome.
- Highly selective D2 receptor full agonist
- ED50 of about 46 nM
- Valuable tool compound for basic research
- Identifies neurobiological mechanisms based on dopamine D2-linked mechanism of action
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Medchemexpress LLC Sumanirole maleate | 179386-44-8 | 99.8% | C15H17N3O5 | 1 ML
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Sumanirole maleate is a highly selective D2 receptor full agonist with an ED50 of approximately 46 nM. It is important in the research of Parkinson's disease and restless leg syndrome. Sumanirole serves as a valuable tool compound for basic research to identify neurobiological mechanisms based on a dopamine D2-linked mechanism of action.
- Highly selective D2 receptor full agonist
- ED50 of approximately 46 nM
- Important in research of Parkinson's disease
- Important in research of restless leg syndrome
- Valuable tool compound for basic research
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Selleck Chemical LLC Indacaterol Maleate S3083-5mg
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Indacaterol (QAB149) is an ultra-long-acting -adrenoceptor agonist with pKi of 7 36 for 1-adrenoceptor and pKi of 5 48 for 2-adrenoceptor
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Medchemexpress LLC Cinepazide Maleate | 26328-04-1 | 99.7% | C26H35N3O9 | 25 MG
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Cinepazide Maleate is a piperazine derivative that acts as a weak calcium channel blocker and a potent vasodilator. It is utilized in research for cerebrovascular diseases, including ischemic stroke and brain infarct.
- Acts as a weak calcium channel blocker
- Potent vasodilator
- Used for research on cerebrovascular diseases
- Suitable for ischemic stroke and brain infarct research
- For research use only
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Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 25 MG
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Neratinib maleate is an orally available, irreversible, and highly selective inhibitor of HER2 and EGFR, intended for research use only. It inhibits the proliferation of cell lines expressing high levels of HER-2 and demonstrates anticancer activities in vivo by reducing tumor growth in a dose-dependent manner in various xenografts.
- Orally available, irreversible, highly selective HER2 and EGFR inhibitor.
- Inhibits proliferation of cell lines with high HER-2 levels.
- Arrests cell cycle at G1-S phase.
- Inhibits MAPK and Akt phosphorylation.
- Down-regulates cyclin D1 levels and induces p27.
- Shows anticancer activities against HER-2 or EGFR expressing cancer cells in vivo.
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Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 25 MG
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Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor that abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. It has potential for Alzheimer's disease research and is also an apoptosis inhibitor. Additionally, it can be used for congenital muscular dystrophy (CMD) research.
- Orally active GAPDH nitrosylation inhibitor.
- Abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
- Potential for Alzheimer's disease research.
- Apoptosis inhibitor.
- Can be used for congenital muscular dystrophy (CMD) research.
- Click chemistry reagent with an alkyne group for CuAAc reactions.
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TARGETMOL CHEMICALS INC DIZOCILPINE MALEATE 50MG
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Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. purity: 99%
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Medchemexpress LLC Quipazine maleate 500mg | 500MG
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Quipazine maleate 500mg | 500MG
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Medchemexpress LLC BRL-44408 maleate | 681806-46-2 | MFCD02262218 | 99.0% | 331.37 g/mol | C17H21N3O4 | 5 MG
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BRL-44408 maleate is a small-molecule α2A-adrenoceptor antagonist used in preclinical pharmacology research. It shows high affinity for α2A receptors (Ki ≈ 8.5 nM) and has demonstrated antidepressant and analgesic activity in animal studies.
- Selective α2A-adrenoceptor antagonist with Ki ≈ 8.5 nM.
- Demonstrates antidepressant and analgesic activity in preclinical models.
- Solid, light brown to brown appearance.
- Molecular weight 331.37 g/mol; formula C17H21N3O4.
- Purity 99.0% (HPLC).
- Soluble in DMSO at 30 mg/mL; may require ultrasonic and warming.
- Store sealed, away from moisture at -20 °C; in solution, store at -80 °C for long-term stability.
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eMolecules 5089-70-3 | (3-Chloropropyl)triethoxysilane | Ambeed | MFCD00018985 | 240.800 | C9H21ClO3Si | 97.000 | CCO[Si](CCCCl)(OCC)OCC | 25g | 491684614
(3-Chloropropyl)triethoxysilane | Ambeed | 5089-70-3 | MFCD00018985 | 240.800 | C9H21ClO3Si | 97.000 | CCO[Si](CCCCl)(OCC)OCC | 25g | 491684614
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eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 25g | 552720844
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 25g | 552720844
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eMolecules 1150114-53-6 | (5-((tert-Butyldimethylsilyl)oxy)-2-fluorophenyl)boronic acid | Ambeed | MFCD11855846 | 270.180 | C12H20BFO3Si | 98.000 | CC(C)(C)[Si](C)(C)Oc1ccc(F)c(c1)B(O)O | 100mg | 717401769
(5-((tert-Butyldimethylsilyl)oxy)-2-fluorophenyl)boronic acid | Ambeed | 1150114-53-6 | MFCD11855846 | 270.180 | C12H20BFO3Si | 98.000 | CC(C)(C)[Si](C)(C)Oc1ccc(F)c(c1)B(O)O | 100mg | 717401769
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