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Filtered Search Results
Medchemexpress LLC Perhexiline maleate | 6724-53-4 | MFCD00057329 | 98.0% | 393.56 | C23H39NO4 | 10 MG
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Perhexiline maleate is the maleate salt of perhexiline, a small-molecule inhibitor of carnitine palmitoyltransferase 1 and 2 (CPT1/CPT2) used in preclinical research to probe mitochondrial fatty-acid metabolism, cancer biology, and cardiovascular disease models. It is provided as a solid salt intended for biochemical and cell-based assays.
- Inhibits CPT1 and CPT2, reducing fatty-acid oxidation
- Maleate salt form improves aqueous handling for assays
- Available in research-scale quantities, including 10 mg
- High reported purity suitable for in vitro and preclinical studies
- Documented chemical identifiers include CAS 6724-53-4 and molecular weight 393.56
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.8% | C28H32N2O7 | 1 ML
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Indacaterol maleate is an orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It functions by inhibiting NF-κB activity in a β-arrestin2-dependent manner. This chemical property contributes to preventing further lung damage and improving lung function in conditions like chronic obstructive pulmonary disorder (COPD). It also has potential applications in cardiovascular disease research.
- Acts as an ultra-long-acting β2 adrenergic receptor (ADRB2) agonist.
- Inhibits NF-κB activity via a β-arrestin2-dependent mechanism.
- Suppresses MMP-9 mRNA expression and activity.
- Reduces cell migration and inhibits NF-κB nuclear translocation.
- Active in normalizing cardiac remodeling in heart failure models.
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Selleck Chemical LLC Perhexiline maleate
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Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 M and 148 M for rat heart CPT1 and liver CPT1 respectively and also inhibits carnitine palmitoyltransferase 2 (CPT2)
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Selleck Chemical LLC Cediranib Maleate S5242-10mg
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Cediranib Maleate (AZD2171) is the maleate salt of Cediranib which is a potent inhibitor of VEGFR with IC50 of 1 nM and also inhibits Flt1/4 with IC50 of 5 nM/ 3 nM
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Chem-Impex International, Inc. Dimethyl acetylenedicarboxylate | 762-42-5 | MFCD00008456 | 100G
Dimethyl acetylenedicarboxylate, 762-42-5, MFCD00008456, 100G
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eMolecules 103-60-6 | 2-Phenoxyethyl isobutyrate | Ambeed | MFCD00027363 | 208.257 | C12H16O3 | 98.000 | CC(C)C(=O)OCCOc1ccccc1 | 25g | 490489950
2-Phenoxyethyl isobutyrate | Ambeed | 103-60-6 | MFCD00027363 | 208.257 | C12H16O3 | 98.000 | CC(C)C(=O)OCCOc1ccccc1 | 25g | 490489950
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Selleck Chemical LLC Indacaterol Maleate S3083-1g
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Indacaterol (QAB149) is an ultra-long-acting -adrenoceptor agonist with pKi of 7 36 for 1-adrenoceptor and pKi of 5 48 for 2-adrenoceptor
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Ambeed 2-BROMOETHYL METHACRYLATE -25G
2-Bromoethyl methacrylate | 4513-56-8 | MFCD00045051 |
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Medchemexpress LLC Trimebutine (maleate) | 34140-59-5 | 99.7% | 1 ML
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Trimebutine (maleate) | 34140-59-5 | 99.7% | 1 ML
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1PLUSCHEM LLC Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
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TARGETMOL CHEMICALS INC FLUPIRTINE MALEATE 200MG
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Also available in 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Flupirtine maleate (Katadolon maleate) a centrally acting non-opioid analgesia is the salt form of Flupirtine. It is an NMDA receptor antagonist and also a specific neuronal potassium channel opener. purity: 99%
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 99.9% | 541.58 | 5 MG
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Filgotinib maleate is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It effectively inhibits JAK1, JAK2, JAK3, and TYK2. It also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. It can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
- Inhibits differentiation of Th2 cells and Th1 cells.
- Produces dose-dependent bone damage protection.
- Prevents the development of inflammation in animal models of collagen-induced arthritis.
- Reduces inflammatory cell infiltration.
- Protects articular cartilage and bone.
- Reduces serum levels of inflammatory cytokines and chemokines.
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Ambeed tertButyl propiolate
tert-Butyl propiolate, 13831-03-3, 95%
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Medchemexpress LLC (S)-timolol maleate | 26921-17-5 | MFCD00058356 | 100.0% | 432.49 | C17H28N4O7S | 10 MG
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(S)-Timolol maleate is the S-enantiomer of timolol supplied as the maleate salt and provided as an analytical/research standard for pharmacological testing, method development, and quality control. It is a non-cardioselective, hydrophilic β-adrenoceptor blocker commonly used in research related to intraocular pressure and cardiovascular effects.
- Analytical standard for method development and quality control.
- S-enantiomer maleate salt with defined stereochemistry.
- High purity suitable for HPLC and reference standard use.
- Molecular weight 432.49 and formula C17H28N4O7S.
- Store sealed at 4°C, protected from light and moisture.
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 50 MG
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Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It inhibits JAK1, JAK2, JAK3, and TYK2 with varying IC50 values. This compound also demonstrates the ability to inhibit HIV-1 driven gene transcription and reduce the proliferation of HIV-1 infected cells, making it suitable for studies related to rheumatoid arthritis and inflammatory bowel disease.
- Selectively inhibits JAK1
- Possesses anti-inflammatory and antiviral properties
- Inhibits HIV-1 driven gene transcription
- Reduces proliferation of HIV-1 infected cells
- Applicable for rheumatoid arthritis research
- Applicable for inflammatory bowel disease research
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