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Dicarboxylic acids and derivatives

Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.

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1

Medchemexpress LLC PKUMDL-LC-101-D04 1g | 2143896-83-5 | 378.94 | C14H23ClN4O2S2 | 1 G
SDP

PKUMDL-LC-101-D04 is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) supplied as a hydrochloride research chemical. It increases GPX4 enzymatic activity (reported pEC50 = 4.7) and has been used in cell and animal studies to inhibit ferroptosis and reduce inflammation. Molecular formula C14H23ClN4O2S2; molecular weight 378.94 Da.

  • Allosteric activator of glutathione peroxidase 4 (GPX4).
  • Reported activity pEC50 = 4.7 in biochemical assays.
  • Hydrochloride salt form for improved stability and handling.
  • Molecular formula C14H23ClN4O2S2, molecular weight 378.94 Da.
  • Provided as a research reagent; not for human use.
  • Typical pack size: 1 g.

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2

Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻¹ | C29H58NO8P | 100 MG
SDP

1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a phosphatidylethanolamine derivative bearing two lauroyl (C12:0) acyl chains. It is a research-grade lipid commonly used for liposome formulation and membrane model studies; typical properties include a molecular weight of 579.75 g·mol⁻¹ and high purity (98.0%).

  • Phosphatidylethanolamine lipid with two lauroyl (C12:0) chains.
  • Suitable for liposome synthesis and membrane model studies.
  • High purity (98.0%) for research applications.
  • Molecular formula C29H58NO8P and molecular weight 579.75 g·mol⁻¹.

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3

Medchemexpress LLC 1,2-dilauroyl-3-chloropropanediol | 1051389-99-1 | MFCD34647394 | >98.0% | 475.14 g·mol⁻¹ | C27H51ClO4 | 5 MG
SDP

1,2-dilauroyl-3-chloropropanediol is a chloropropanediol ester used as a research-grade lipid reagent for analytical and synthetic applications. It has molecular formula C27H51ClO4, molecular weight ≈475.14 g·mol⁻¹, and CAS 1051389-99-1. The compound is typically supplied as a solid with reported purity >98% and is recommended to be stored at -20 °C.

  • High purity (>98%) suitable for analytical and synthetic workflows.
  • Well-defined molecular identity: C27H51ClO4; MW 475.14 g·mol⁻¹; CAS 1051389-99-1.
  • Solid form facilitates accurate weighing and handling.
  • Small pack sizes available for method development and reference use.
  • Recommended cold storage to maintain stability.

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4

Medchemexpress LLC GlyH-101 | 328541-79-3 | MFCD01532954 | 99.7% | 493.15 g/mol | C19H15Br2N3O3 | 10 MG
SDP

GlyH-101 is a research-grade small-molecule inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR). It is used in cellular and electrophysiological studies to block CFTR-mediated chloride conductance and has reported antiproliferative activity. Supplied as a purified, characterized compound for laboratory research.

  • Potent CFTR inhibitor for cellular and electrophysiology assays.
  • Reversible blockade of VSORC conductance.
  • High purity (99.7%).
  • Molecular weight 493.15 g/mol.
  • Molecular formula C19H15Br2N3O3.
  • Supplied as a 10 mg vial for research use.

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5

Medchemexpress LLC ULK-101 25mg | 2443816-45-1 | 460.45 | C22H16F4N4OS | 25 MG
SDP

ULK-101 is a potent, selective small-molecule inhibitor of ULK1 used in cellular and biochemical research to suppress autophagy and sensitize cancer cells to nutrient stress.

  • Potent ULK1 inhibition (IC50 = 1.6 nM) with lower activity on ULK2 (IC50 = 30 nM).
  • High purity suitable for research applications (99.91%).
  • Available as a powder in multiple pack sizes, including 25 MG, and as DMSO solution formats.
  • Storage-stable when kept at recommended temperatures for powder and solutions.
  • Molecular weight 460.45 and molecular formula C22H16F4N4OS.

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6

Medchemexpress LLC ULK-101 1mg | 2443816-45-1 | 1 MG
SDP

ULK-101 is a potent, selective small-molecule inhibitor of ULK1 (unc-51-like autophagy activating kinase 1) that suppresses autophagy and can sensitize cancer cells to nutrient stress. It is supplied as a research-grade solid for in vitro studies.

  • Potent ULK1 inhibition; reported low-nanomolar IC50 for ULK1, ULK2 ~30 nM
  • Suppresses autophagy and sensitizes cancer cells to nutrient stress
  • Molecular formula C22H16F4N4OS and molecular weight ~460.4 g/mol
  • Provided as a 1 mg quantity suitable for assay development and biochemical studies

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7

Medchemexpress LLC BNC-101 1mg | 1mg
SDP

BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)

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8

Medchemexpress LLC BNC-101 5mg | 5mg
SDP

BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)

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9

Medchemexpress LLC BNC-101 10mg | 10mg
SDP

BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)

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10

Medchemexpress LLC 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | 99.1% | 434.49 g/mol | C24H26N4O4 | 1 ML
SDP

CUDC-101 is a small-molecule inhibitor that targets histone deacetylases (HDAC) and receptor tyrosine kinases EGFR and HER2. It is intended for research use in studies of signaling pathways, anti-proliferative activity, and preclinical cancer models. The compound is supplied as a high-purity reagent suitable for in vitro experiments.

  • Multi-target HDAC, EGFR, and HER2 inhibition
  • High purity suitable for research applications
  • Available as a ready-to-use 10 mM solution in DMSO (1 mL)
  • Confirmed molecular formula and molecular weight for analytical workflows
  • Intended for in vitro and preclinical research use

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11

Medchemexpress LLC Ji-101 | 900573-88-8 | MFCD26142530 | 99.8% | 466.33 | C22H20BrN5O2 | 10 MG
SDP

JI-101 is an orally available multi-kinase inhibitor that targets VEGFR2, PDGFRβ, and EphB4 and has demonstrated potent anti-cancer activity. It is provided as a white to off-white solid powder for research use and is commonly supplied in a 10 mg pack.

  • Orally available multi-kinase inhibitor active against VEGFR2, PDGFRβ, and EphB4.
  • High purity (99.78%).
  • Molecular formula C22H20BrN5O2; molecular weight 466.33 g/mol.
  • White to off-white solid, soluble in DMSO at ≥ 100 mg/mL.
  • Intended for research use only; not for human administration.

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12

Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG
SDP

CUDC-101 is a small-molecule research compound that concurrently inhibits histone deacetylases (HDACs) and receptor tyrosine kinases EGFR and HER2. It is used in preclinical cancer research to study combined epigenetic and kinase-targeted therapies.

  • Potent inhibition of HDAC, EGFR, and HER2 with IC50s of 4.4 nM, 2.4 nM, and 15.7 nM.
  • Contains a hydroxamic acid moiety associated with HDAC activity.
  • High purity (>98.0%) suitable for research applications.
  • Soluble in DMSO at 25 mg/mL (approximately 57.54 mM; may require ultrasonic agitation).
  • Molecular formula C24H26N4O4 and molecular weight 434.49 g/mol.

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13

Medchemexpress LLC AVN-101 hydrochlorid 25mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 25 MG
SDP

AVN-101 hydrochloride is the hydrochloride salt of a brain-penetrant small molecule antagonist of serotonin (5-HT) receptors, supplied for preclinical and in-vitro research. It is provided as a solid with reported high purity for analytical and biological assays.

  • Potent antagonist of 5-HT receptor subtypes (5-HT7, 5-HT6, 5-HT2A, 5-HT2C).
  • High purity: 99.59%.
  • Molecular formula C21H25ClN2; molecular weight 340.89.
  • Available in small research pack sizes, including 25 MG.
  • Provided as hydrochloride salt to improve solubility for assay preparation.
  • For research use only; not for human or veterinary use.

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14

Medchemexpress LLC PKUMDL-LC-101-D04 50mg | 2143896-83-5 | 378.94 g·mol⁻¹ | C14H23ClN4O2S2 | 50 MG
SDP

Small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used as a research tool to study ferroptosis and inflammation. Reported activity includes an approximate pEC50 of 4.7 and an ability to increase GPX4 activity in biochemical assays. Supplied as a solid with good solubility in DMSO for assay preparation.

  • Allosteric activation of glutathione peroxidase 4 with reported pEC50 ≈ 4.7.
  • Shown to increase GPX4 activity to about 150% in biochemical assays.
  • Useful for probing ferroptosis and inflammation pathways in preclinical research.
  • Supplied as a solid with high DMSO solubility for convenient dilution and assay use.
  • Vendor-reported molecular formula and molecular weight provided for analytical reference.

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15

Medchemexpress LLC Vnt-101 | 2894060-67-2 | 456.41 | C21H23F3N2O6 | 10 MG
SDP

VNT-101 is a small-molecule, orally active inhibitor of influenza A virus nucleoprotein (NP) oligomerization. It disrupts NP-NP protein-protein interactions to destabilize the viral ribonucleoprotein complex and has been used in vitro and in vivo to study antiviral activity across multiple influenza A subtypes.

  • Disrupts nucleoprotein oligomerization to inhibit viral replication.
  • Orally bioavailable small molecule suitable for in vivo studies.
  • Demonstrated activity against multiple influenza A subtypes.
  • Molecular weight 456.41 and molecular formula C21H23F3N2O6.
  • CAS number 2894060-67-2 for substance identification.
  • Supplied as a solid for research use with supporting characterization data.

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