Tricarboxylic acids and derivatives
Medchemexpress LLC 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo-. | 108466-89-3 | 263.29 | 10 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by this linker: one targeting an E3 ubiquitin ligase and the other for a specific protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Functions as a PEG-based PROTAC linker
- Essential for the synthesis of PROTACs
- Enables selective degradation of target proteins
- Utilizes the intracellular ubiquitin-proteasome system
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 50 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize two ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- Other ligand binds to the target protein
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- High solubility in DMSO (100 mg/mL)
Medchemexpress LLC 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo- | 108466-89-3 | 263.29 | 25 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Contains two different ligands connected by a linker
- Includes a ligand for an E3 ubiquitin ligase
- Includes a ligand for a target protein
Medchemexpress LLC Arimoclomol citrate | 368860-21-3 | 99.8% | 505.90 g·mol⁻¹ | C20H28ClN3O10 | 1 ML
Arimoclomol citrate is the citrate salt of arimoclomol, a heat-shock protein (HSP) co-inducer used in research to enhance Hsp expression, reduce protein aggregation, and study neurodegenerative conditions such as Niemann-Pick disease type C. Supplied for in vitro and preclinical laboratory work, it is available as a solution in DMSO and in multiple solid pack sizes.
- High reported purity (99.8%).
- Supplied as a 10 mM solution in DMSO for ready use.
- Also available in solid form for flexible dosing and formulation.
- Molecular weight 505.90 g·mol⁻¹ for stoichiometric calculations.
- Facilitates studies of Hsp induction and protein aggregation.
- Suitable for in vitro and preclinical model applications.
Selleck Chemical LLC Edoxaban tosylate Monohydrate
Edoxaban (DU-176b) is a selective factor Xa inhibitor with Ki of 0 561 nM 10 000-fold selectivity over thrombin and FIXa and is also an orally bioavailable anticoagulant drug
Medchemexpress LLC 2'-deoxyuridine-5'-triphosphate trisodium salt | 102814-08-4 | MFCD00084701 | 99.7% | 534.09 | C9H12N2Na3O14P3 | 5 MG
dUTP trisodium (2'-deoxyuridine-5'-triphosphate trisodium salt) is the trisodium salt of dUTP, a deoxynucleotide triphosphate used as a dTTP substitute in PCR and related enzymatic applications to produce uracil-containing DNA. Supplied as a solid with high reported purity, it is intended for workflows that require uracil incorporation or UDG-based carryover prevention.
- High purity (99.74%) suitable for sensitive enzymatic reactions.
- Provided as a white to off-white solid, 5 mg pack size.
- Trisodium salt form for stable handling and solubility.
- Compatible with PCR and RT-PCR to produce uracil-containing PCR products.
- Supports uracil-DNA glycosylase (UDG)-based carryover prevention.
- Store sealed, away from moisture; in solution: -80°C (up to 6 months), -20°C (up to 1 month).
U.S. Pharmacopeia Triethyl Citrate | 77-93-0 | MFCD00009201 | 100 mg
Molecular formula C12-H20-O7 | Molecular weight 276.29 | Melting Point -67 °F (-55 °C) | Boiling Point 561.2 °F (294 °C) | Synonyms: Ethyl citrate
Selleck Chemical LLC Oxeladin Citrate S4402-25mg
Oxeladin citrate (OL) a cough suppressant is a highly potent and effective drug applied in the treatment of all types of cough of various etiologies
Medchemexpress LLC (E/Z)-Zotiraciclib citrate | 1204918-73-9 | C29H32N4O8 | 100 MG
(E/Z)-Zotiraciclib citrate is a potent inhibitor targeting CDK2, JAK2, and FLT3. It is intended for research use only.
- Potent CDK2, JAK2, and FLT3 inhibitor
- Purity: 99.83%
- Molecular weight: 564.59
- Chemical formula: C29H32N4O8
- CAS number: 1204918-73-9
- Appearance: Solid, off-white to light yellow
- Solubility in DMSO: 250 mg/mL
Crescent Chemical Co Inc CITRIC ACID-NA3-SALT-2H2O
Citric acid-Na3-salt-2H2O analytical grade, Ph. Eur. Size - 1KG Storage Conditions - +15 °C TO +30 °C Catalog Number - 38642.02 CAS 1545801
TARGETMOL CHEMICALS INC SPD-473 citrate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SPD-473 citrate (BTS 74398 citrate) is a dopamine reuptake inhibitor, a norepinephrine transporter protein (NET) inhibitor, and a 5-hydroxytryptamine reuptake inhibitor, and is used in the study of neurological disorders and endocrine and metabolic diseases. Purity 99.37%
Medchemexpress LLC Citrate synthase | 9027-96-7 | ~98 KDa dimer (49 KDa monomer) | 1000 U
Citrate synthase catalyzes the initial reaction of the citric acid cycle, facilitating the condensation of acetyl-CoA and oxaloacetate to produce citrate. This enzyme is primarily found within the mitochondrial matrix of eukaryotic cells.
- Catalyzes the condensation of acetyl-CoA and oxaloacetate
- Forms citrate, initiating the citric acid cycle
- Localized in the mitochondrial matrix of eukaryotic cells
- Specific activity of ≥100 U/mg protein
- Unit defined as 1.0 μmole of citrate formed per minute at pH 8.0 at 37°C
- Liquid appearance
- Colorless to light yellow
- Molecular weight of ~98 KDa dimer (49 KDa monomer)
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 5 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- For research use only
- Molecular formula: C11H21NO6
- Appearance: Liquid, colorless to light yellow
- Storage: Pure form at -20°C for 3 years, 4°C for 2 years
- Storage: In solvent at -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 100 mg/mL
Sigma Aldrich Fine Chemicals Biosciences Trisodium citrate dihydrate meets USP testing specifications | 6132-04-3 | MFCD00150031 | 25KG
Trisodium citrate dihydrate meets USP testing specifications | Purity: 99.0-100.5% anhydrous basis | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 25KG
Medchemexpress LLC Citrate synthase | 9027-96-7 | MFCD00131495 | ~98 KDa dimer | 250 U
Citrate synthase catalyzes the first reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is localized within eukaryotic cells in the mitochondrial matrix.
- Catalyzes the first reaction of the citric acid cycle
- Condenses acetyl-CoA and oxaloacetate to form citrate
- Localized in the mitochondrial matrix
- Specific activity: ≥100 U/mg protein
- Appearance: Colorless to light yellow liquid
- Source: Microorganism