Tricarboxylic acids and derivatives
Medchemexpress LLC (E/Z)-Zotiraciclib hydrochloride | 1321626-25-8 | C23H25ClN4O | 5 MG
(E/Z)-Zotiraciclib ((E/Z)-TG02) is an orally active inhibitor of CDK2, JAK2, and FLT3 with IC50s of 13, 73, and 56 nM, respectively. It effectively inhibits the proliferation of cancer cells, making it suitable for cancer research.
- Orally active inhibitor of CDK2, JAK2, and FLT3
- Inhibits proliferation of cancer cells
- Useful for cancer research
- Potently inhibits the CDK2 biomarker pRb
TARGETMOL CHEMICALS INC SPD-473 citrate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SPD-473 citrate (BTS 74398 citrate) is a dopamine reuptake inhibitor, a norepinephrine transporter protein (NET) inhibitor, and a 5-hydroxytryptamine reuptake inhibitor, and is used in the study of neurological disorders and endocrine and metabolic diseases. Purity 99.37%
Medchemexpress LLC 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo- | 108466-89-3 | MFCD17019374 | 263.29 | 1 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs utilize two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein, to selectively degrade target proteins through the intracellular ubiquitin-proteasome system. This product is intended for research use only.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- For research use only
- Molecular weight: 263.29
- Formula: C11H21NO6
- CAS no: 108466-89-3
- Appearance: Colorless to light yellow liquid
- Purity (LCMS): 99.87%
Medchemexpress LLC (E/Z)-Zotiraciclib citrate | 1204918-73-9 | C29H32N4O8 | 100 MG
(E/Z)-Zotiraciclib citrate is a potent inhibitor targeting CDK2, JAK2, and FLT3. It is intended for research use only.
- Potent CDK2, JAK2, and FLT3 inhibitor
- Purity: 99.83%
- Molecular weight: 564.59
- Chemical formula: C29H32N4O8
- CAS number: 1204918-73-9
- Appearance: Solid, off-white to light yellow
- Solubility in DMSO: 250 mg/mL
Alkali Scientific L (+) Rhamnose, Monohydrate, 5 Kg
L (+) Rhamnose Monohydrate, 5 kilograms, is a bulk quantity of this high-purity sugar used in large-scale laboratory experiments, especially in studies involving microbiology and plant metabolism. This form of rhamnose is essential for fermentation processes, bacterial growth studies, and enzyme assays that require a consistent and controlled sugar source. The 5kg quantity is ideal for extensive research applications, supporting high-throughput testing and long-term experiments. Rhamnose plays a critical role in the study of cell wall biosynthesis, bacterial metabolism, and microbial enzymatic activity, offering reliable results in biochemical and environmental testing protocols.
![Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 1 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660960.jpg-250.jpg)
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 1 Kg
Sodium Citrate, Trisodium Salt, Dihydrate, laboratory grade, is commonly used in buffer preparation and other laboratory applications. This 1 kg package of trisodium citrate dihydrate is a versatile reagent that plays a critical role in maintaining pH balance during chemical and biological experiments. Sodium citrate is widely used in the preparation of anticoagulants for blood samples, in the formulation of buffers for molecular biology applications, and in various enzymatic assays. The trisodium salt form of citrate ensures effective buffering capabilities, maintaining stability across a broad range of pH values. This reagent is ideal for use in biochemical research and laboratory settings that require precise pH control.
Sigma Aldrich Fine Chemicals Biosciences Propyl 4-hydroxybenzoate BioXtra | 94-13-3 | MFCD00002354 | 500G
Propyl 4-hydroxybenzoate BioXtra | Mol Wt: 180.2 | 94-13-3 | MFCD00002354 | 500G
Medchemexpress LLC Adenosine 5'-(α,β-methylene) diphosphate (triammonium) | 99.9% | 476.32 | 25 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor that can be used for research of the ATP-adenosine pathway.
- CD73 inhibitor.
- Can be used for the research of the ATP-adenosine pathway.
- Inhibits 5'-AMP induced adenosine formation in A498 cells (in vitro).
![Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 25 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659812.jpg-250.jpg)
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 25 Kg
Sodium Citrate, Trisodium Salt, Dihydrate, laboratory grade, is available in a 25 kg package for high-volume applications in buffer preparation and other laboratory processes. Sodium citrate is a crucial reagent in many biological and chemical experiments, particularly for maintaining pH stability in solution. This large quantity of trisodium citrate dihydrate is ideal for laboratories and research institutions that require bulk quantities for routine preparation of buffer solutions, including those used in electrophoresis, chromatography, and enzyme assays. Its versatility makes it a common choice in molecular biology, biochemistry, and diagnostic laboratories for controlling pH levels and maintaining consistent experimental conditions.
Medchemexpress LLC Dicresulene diammoni 5mg | 5MG
Dicresulene diammonium is an impurity of Policresulen an organic acid with hemostatic antimicrobial and antiviral activities[1 [2
Medchemexpress LLC PF-543 Citrate | 1415562-83-2 | C33H39NO11S | 1 ML
PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) is a potent, selective, reversible, and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. It demonstrates over 100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. It is known to induce apoptosis, necrosis, and autophagy.
- Potent, selective, reversible, and sphingosine-competitive SPHK1 inhibitor
- IC50 of 2 nM and Ki of 3.6 nM for SPHK1
- Over 100-fold selectivity for SPHK1 over SPHK2
- Effective inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM
- Induces apoptosis, necrosis, and autophagy
eMolecules 1021868-83-6 | Medchem Express | ARL67156 (trisodium) | 1mg | 527574555 | HY-103265 | 785.055 | C15H21Br2N5Na3O12P3
Ambeed | 4-Fluoro-3-hydroxybenzaldehyde | 250mg | 572969521 | A543929 | 103438-85-3 | MFCD11110190 | 140.113 | C7H5FO2
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Medchemexpress LLC Toremifene (Citrate) | 89778-27-8 | 99.9% | C32H36ClNO8 | 1 ML
Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) developed for the prevention of osteoporosis and other adverse effects from Androgen Deprivation Therapy (ADT) in prostate cancer. It also potently inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.07 μM and 2.6 μM, respectively.
- Second-generation selective estrogen-receptor modulator (SERM).
- Developed for the prevention of osteoporosis.
- Potently inhibits infectious EBOV Zaire and Marburg (MARV).
- Used in development for the prevention of adverse effects from ADT with prostate cancer.
- Inhibits growth of Ac-1 cells in vitro.
- Stable under recommended storage conditions.
- Soluble in DMSO (≥ 100 mg/mL).
Medchemexpress LLC Citrate synthase | 9027-96-7 | MFCD00131495 | ~98 KDa dimer | 250 U
Citrate synthase catalyzes the first reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is localized within eukaryotic cells in the mitochondrial matrix.
- Catalyzes the first reaction of the citric acid cycle
- Condenses acetyl-CoA and oxaloacetate to form citrate
- Localized in the mitochondrial matrix
- Specific activity: ≥100 U/mg protein
- Appearance: Colorless to light yellow liquid
- Source: Microorganism