Tricarboxylic acids and derivatives
Medchemexpress LLC Citrate synthase | 9027-96-7 | MFCD00131495 | ~98 KDa dimer | 250 U
Citrate synthase catalyzes the first reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is localized within eukaryotic cells in the mitochondrial matrix.
- Catalyzes the first reaction of the citric acid cycle
- Condenses acetyl-CoA and oxaloacetate to form citrate
- Localized in the mitochondrial matrix
- Specific activity: ≥100 U/mg protein
- Appearance: Colorless to light yellow liquid
- Source: Microorganism
Selleck Chemical LLC Edoxaban tosylate Monohydrate
Edoxaban (DU-176b) is a selective factor Xa inhibitor with Ki of 0 561 nM 10 000-fold selectivity over thrombin and FIXa and is also an orally bioavailable anticoagulant drug
Medchemexpress LLC 1-naphthol-3,6,8-trisulfonic acid trisodium salt | 31894-34-5 | MFCD03427540 | 97.0% | 450.31 g/mol | C10H5Na3O10S3 | 10MG
ζ-Stat trisodium (1-naphthol-3,6,8-trisulfonic acid trisodium salt) is the trisodium salt research reagent that functions as a selective atypical protein kinase C-ζ (PKC-ζ) inhibitor with reported in vitro antitumor activity (IC50 ≈ 5 μM). It reduces proliferation and induces apoptosis in certain melanoma cell lines and is supplied as a solid for biochemical and cell-based assays.
- Selective atypical PKC-ζ inhibitor (IC50 ≈ 5 μM).
- Demonstrated antiproliferative and pro-apoptotic activity in melanoma cell lines.
- Solid, light yellow appearance; purity 97.0%.
- Water soluble: 12.5 mg/mL in H2O with ultrasonic/warming (heat to 60°C).
- Store sealed, away from moisture; recommend 4°C; in solution keep at -80°C (6 months) or -20°C (1 month).
- Available in small research pack sizes including 10 mg.
Medchemexpress LLC GS-443902 trisodium | 1355050-21-3 | 10MG
GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1 1 M 5 M for RSV RdRp and HCV RdRp respectively GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734)[1][2]
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 100 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker; one binds to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Peg-based protac linker
- Used in the synthesis of protacs
- Enables selective degradation of target proteins
Accela Chembio Inc Tri-o-acetyl-d-glucal | 25g | 2873-29-2 | MFCD00063253 | 97+% | Shelf Life: 720 Days | Light Sensitive
Tri-o-acetyl-d-glucal | 25g | 2873-29-2 | MFCD00063253 | 97+% | Shelf Life: 720 Days | Light Sensitive
Medchemexpress LLC Subasumstat | 1858276-04-6 | 578.10 | 100 MG
Subasumstat (TAK-981) is a first-in-class and selective inhibitor of the SUMOylation enzymatic cascade, demonstrating potential immune-activating and antineoplastic activities. It increases the production of type 1 IFN, enhancing type 1 IFN-mediated signaling, activating innate effector cells, and improving antitumor innate immune responses. A single subcutaneous injection induces activation of dendritic cells.
- First-in-class selective inhibitor of SUMOylation enzymatic cascade
- Potential immune-activating activities
- Potential antineoplastic activities
- Increases production of type 1 IFN
- Enhances antitumor innate immune responses
- Activates innate effector cells
- Induces activation of dendritic cells
Medchemexpress LLC Methadp triammonium (adenosine 5'-(α,β-methylene)diphosphate triammonium) | 99.9% | 476.32 | 100 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. It can be used for the research of ATP-adenosine pathway.
- Acts as a CD73 inhibitor
- Used for research of the ATP-adenosine pathway
- Inhibits 5'-AMP induced adenosine formation in A498 cells
Medchemexpress LLC SPD-473 citrate | 161190-26-7 | 99.8% | 552.47 g/mol | C23H31Cl2NO8S | 5 MG
SPD-473 citrate is the citrate salt of a small-molecule triple reuptake inhibitor that blocks serotonin, dopamine, and norepinephrine transport. It is supplied as a solid research chemical for in vitro and in vivo neuroscience and pharmacology studies and is accompanied by analytical and safety documentation.
- Triple reuptake inhibitor activity for serotonin, dopamine, and norepinephrine.
- Citrate salt form supplied as a solid.
- Supplied in small research quantities (1-100 mg) suitable for laboratory studies.
- High purity: 99.8%.
- Analytical data and documentation available, including data sheet, SDS, COA, HNMR, and LCMS.
Medchemexpress LLC Potassium phosphate tribasic | 7778-53-2 | MFCD00036295 | 98.7% | 212.27 g/mol | K3O4P | 1g
Tripotassium phosphate is a kind of biological materials or organic compounds that are widely used in life science research[1]
Gold Biotechnology Inc TCEP-HCl 25 g
TCEP (Tris (2-Carboxyethyl) phosphine Hydrochloride) is an odorless reducing agent suitable for protein applications and in the preparation for electrophoresis. TCEP is water soluble, is stable in a variety of solutions and is particularly useful in the labeling of cysteine residues with maleimides, preventing the cysteines from forming disulfide bonds.
Accela Chembio Inc Triethyl Methanetricarboxylate | 100g | 6279-86-3 | MFCD00009150 | 95+% | D: 1.095 | Shelf Life: 1080 Days | Regular
Triethyl Methanetricarboxylate | 100g | 6279-86-3 | MFCD00009150 | 95+% | D: 1.095 | Shelf Life: 1080 Days | Regular