Tricarboxylic acids and derivatives
Medchemexpress LLC Magnesium citrate 100mg
Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2]
Medchemexpress LLC Enclomiphene citrate | 7599-79-3 | 99.9% | 598.09 | C32H36ClNO8 | 1 ML
Enclomiphene citrate is a research-grade, non-steroidal estrogen receptor antagonist supplied as a solid or as a ready-to-use 10 mM solution in DMSO for in vitro and in vivo studies.
- High purity typically 99.93%.
- Available as a 10 mM solution (1 mL) in DMSO or as mg-scale solids.
- Used for studies of ovarian dysfunction, testosterone deficiency, and male hypogonadism.
- Molecular weight 598.09, formula C32H36ClNO8, CAS 7599-79-3.
- Store powder at 4°C; stock solutions at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC MRTX9768 | 2629314-68-5 | 99.48% | 424.43 | 50 MG
MRTX9768 is a potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor. It inhibits SDMA and cell proliferation in HCT116 MTAP-del cells with marked selectivity over HCT116 MTAP-WT cells. This compound selectively targets MTAP/CDKN2A-deleted tumors, such as glioblastoma, and exhibits a favorable ADME profile.
- Potent and selective PRMT5-MTA complex inhibitor
- Inhibits SDMA and cell proliferation in MTAP-del cells
- Demonstrates dose-dependent inhibition of SDMA in MTAP-del tumors
- Selectively targets MTAP/CDKN2A-deleted tumors, including glioblastoma
- Favorable ADME profile with high bioavailability and moderate to high clearance
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | C15H22O8S | 10MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker with a tosyl cap and a three-unit polyethylene glycol spacer terminating in a carboxylic acid. It is designed for use in the synthesis of PROTACs and other bifunctional molecules where a short, flexible, polar spacer and a carboxyl functional handle are required.
- Tosyl-capped PEG3 spacer ending in a carboxylic acid for conjugation.
- Provides a short, flexible, hydrophilic linker suitable for cellular applications.
- Terminal carboxyl group enables amide or ester coupling chemistries.
- Compatible with solid-phase and solution-phase synthetic workflows.
- Supplied in research-scale quantities for medicinal chemistry and PROTAC development.
- Molecular formula C15H22O8S, molecular weight ≈362.40 g/mol.
Medchemexpress LLC Gefapixant citrate | 2310299-91-1 | 99.2% | 545.52 g/mol | C20H27N5O11S | 5 MG
Gefapixant citrate is the citrate salt of gefapixant, an orally active P2X3 receptor antagonist used in research on chronic cough and pain-related indications. Supplied as a research-grade solid with high purity, it is suitable for in vitro and in vivo studies and is accompanied by technical documentation for analytical use.
- Potent P2X3 receptor antagonist with low-nanomolar activity.
- High purity suitable for research applications.
- Available in small solid quantities for dose-ranging studies.
- Includes datasheet, certificate of analysis, and safety data sheet documentation.
- Soluble stock solutions offered for convenient preparation.
Selleck Chemical LLC Orphenadrine Citrate S2054-50mg
Orphenadrine Citrate is a skeletal muscle relaxant it acts in the central nervous system to produce its muscle relaxant effects
Medchemexpress LLC ARL67156 trisodium hydrate | MFCD12910436 | 99.9% | 834.61 g/mol | C15H23Br2N5Na3O13P3 | 1 MG
ARL67156 trisodium hydrate is the trisodium salt hydrate form of ARL67156 (FPL 67156), a small-molecule inhibitor of ecto-ATPases used in research to study extracellular ATP signaling and disease models such as calcific aortic valve disease and asthma.
- Inhibits ecto-ATPase enzymes, including NTPDase1 (CD39), NTPDase3, and NPP1.
- Reported Ki values: 11 μM, 18 μM, and 12 μM for NTPDase1, NTPDase3, and NPP1, respectively.
- Purity 99.94% as reported on the product page.
- Supplied as a trisodium hydrate salt.
- Available in small research quantities (for example, 1 mg and 5 mg sizes).
Medchemexpress LLC Fmoc-NH-PEG1-CH2COOH | 260367-12-2 | 99.5% | 341.36 g/mol | C19H19NO5 | 1 G
Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG-based linker with a terminal carboxylic acid, designed for installation of linkers in medicinal chemistry workflows such as ADC and PROTAC synthesis.
- Used in antibody-drug conjugate linker synthesis.
- Used in proteolysis-targeting chimera (PROTAC) synthesis.
- Contains an Fmoc-protected amine and a terminal carboxylic acid for conjugation.
- White to off-white solid with good purity for research applications.
- Available in multiple sizes, including 1 g, for flexible laboratory use.
Chem-Impex International, Inc. Sodium citrate dihydrate | 6132-04-3 | MFCD00150031 | 2.5KG
Sodium citrate dihydrate, 6132-04-3, MFCD00150031, 2.5KG
Medchemexpress LLC 5,8,11,14,17,20-hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | 99.4% | 561.62 | C29H39NO10 | 250 MG
Fmoc-NH-PEG6-CH2COOH is an Fmoc-protected polyethylene glycol (PEG6) linker with a terminal carboxylic acid, supplied for research use as a cleavable linker for antibody-drug conjugates and as a PEG-based PROTAC linker in targeted protein degradation research.
- Fmoc-protected amine with terminal carboxylic acid functionality.
- Suitable for ADC and PROTAC linker synthesis.
- Reported purity 99.4% and molecular weight 561.62.
- Molecular formula C29H39NO10.
- Available in small-scale pack sizes including 250 MG.
Medchemexpress LLC Mosapride citrate | 112885-42-4 | 99.96% | 5 MG
Mosapride citrate is an orally active gastroenterokinetic compound, acting as a 5HT4 agonist and a CYP inducer. It demonstrates a concentration-dependent inhibitory effect on Kv4.3 with an IC50 value of 15.2 μM. This compound is suitable for use in the study of gastrointestinal diseases.
- Acts as a 5HT4 agonist
- Functions as a CYP inducer
- Exhibits concentration-dependent inhibitory effect on Kv4.3 with an IC50 of 15.2 μM
- Promotes gastric emptying
- Relieves NSAID-induced ulcers by activating the 5-HT4 receptor
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.4% | 5 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This compound leverages the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Utilized in antibody-drug conjugate (ADC) synthesis
- Used in PROTAC synthesis
- Leverages intracellular ubiquitin-proteasome system
Medchemexpress LLC Mosapride citrate | 112885-42-4 | 99.9% | 1 ML
Mosapride citrate is an orally active gastroenterokinetic compound. It acts as a 5HT4 agonist and a CYP inducer. It exhibits a concentration-dependent inhibitory effect on Kv4.3, with an IC50 value of 15.2 μM. Mosapride citrate is used in the study of gastrointestinal diseases.
- Orally active gastroenterokinetic compound
- 5HT4 agonist
- CYP inducer
- Inhibitory effect on Kv4.3
- Useful for studying gastrointestinal diseases