Pyrazoles
![eMolecules 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | Ambeed | 857530-80-4 | MFCD05663852 | 222.100 | C11H19BN2O2 | 97.000 | Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1 | 10g | 525048419](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2041013.JPG-250.jpg)
eMolecules 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | Ambeed | 857530-80-4 | MFCD05663852 | 222.100 | C11H19BN2O2 | 97.000 | Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1 | 10g | 525048419
3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | Ambeed | 857530-80-4 | MFCD05663852 | 222.100 | C11H19BN2O2 | 97.000 | Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1 | 10g | 525048419
Medchemexpress LLC 1,3,5-Trimethylpyrazole | 1072-91-9 | MFCD00015536 | 500 MG
1,3,5-Trimethylpyrazole is a compound primarily used for chemical synthesis.
- High purity of 99.91%
- Molecular weight of 110.16
- Chemical formula C6H10N2
- Appearance as a solid below 38°C and liquid above 41°C
- Colorless to off-white appearance
- Soluble in DMSO and H2O at 100 mg/mL, requiring ultrasonic for dissolution
- Multiple in vivo dissolution protocols available, including those with DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
- Long-term storage recommendations: -20°C for 3 years, 4°C for 2 years for pure form; -80°C for 6 months, -20°C for 1 month for in solvent
Medchemexpress LLC 1,3-Dimethylpyrazole | 694-48-4 | 96.13 | 1 G
1,3-Dimethylpyrazole is a bioactive compound isolated from Moso Bamboo Root. It is an active small molecule that can be used as a building block for the synthesis of multiple compounds.
Medchemexpress LLC Phthalazinone pyrazole | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 5MG
Phthalazinone pyrazole is a small-molecule Aurora-A kinase inhibitor used in research on cell cycle regulation, apoptosis, and mitosis. It is supplied as a solid and as a DMSO solution for biochemical and cellular assays.
- Potent Aurora-A kinase inhibitor for research use.
- Molecular formula C18H15N5O, molecular weight 317.34 g·mol⁻¹.
- Purity ≥98.0% by HPLC.
- Available as solid (5 mg-100 mg) and solution (10 mM in DMSO, 1 mL).
- Store at 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Provided with datasheet, SDS, and COA for characterization.
Medchemexpress LLC 1,3-Dimethylpyrazole | 694-48-4 | 96.13 | 1 ML
1,3-Dimethylpyrazole is a bioactive compound isolated from Moso Bamboo Root, serving as an active small molecule and building block for the synthesis of multiple compounds. It is supplied as a colorless to light yellow liquid.
- Molecular formula: C5H8N2
- High purity (typically >99%)
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Handle in well-ventilated area, avoiding inhalation, skin, and eye contact
- Wear appropriate personal protective equipment
Medchemexpress LLC 3-Methylpyrazole | 1453-58-3 | 99.5% | C4H6N2 | 5 G
This product is 3-Methylpyrazole, a chemical compound primarily used as a nitrification inhibitor in soil. It also demonstrates the ability to inhibit the metabolism of methylazoxymethanol (MAM) by rat liver microsomes.
- Used as a nitrification inhibitor in soil
- Inhibits MAM metabolism by rat liver microsomes
- Appearance: Light yellow to reddish brown
- Purity (HPLC): 99.5%
- Store pure form at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in H2O (25 mg/mL) and PBS (50 mg/mL)
Medchemexpress LLC 1H-Pyrazole, 3-methyl- | 1453-58-3 | 99.5% | C4H6N2 | 25G
3-Methylpyrazole is utilized as a nitrification inhibitor in soil and has been shown to inhibit the metabolism of MAM by rat liver microsomes in vitro.
- Utilized as a nitrification inhibitor in soil
- Inhibits the metabolism of MAM by rat liver microsomes
- Appears as a light yellow to reddish brown solid below 36.5°C and liquid above 36.5°C
- Store pure form at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in H2O at 25 mg/mL (304.48 mM)
- Soluble in PBS at 50 mg/mL (608.97 mM)
Medchemexpress LLC Phthalazinone pyrazole | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 25MG
Phthalazinone pyrazole is a small-molecule Aurora-A kinase inhibitor provided as a brown to gray solid for biochemical and cellular research. The compound has formula C18H15N5O, molecular weight 317.34 g·mol⁻1, and a reported purity of 98.0%. It is offered in multiple solid sizes and as 10 mM solutions in DMSO, and should be stored protected from light at 4°C (in solvent: -80°C for long term storage).
- Potent Aurora-A kinase inhibitor with low-nanomolar activity.
- High reported purity for assay reliability.
- Multiple solid pack sizes and solution formats available.
- Brown to gray solid; handle and store protected from light.
- Accompanied by supporting documents such as data sheet, COA, and SDS.
![Medchemexpress LLC 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236420.png-250.jpg)
Medchemexpress LLC 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 50MG
Phthalazinone pyrazole is a potent, selective, orally active small-molecule inhibitor of Aurora-A kinase intended for laboratory research. It arrests mitosis and induces apoptosis in proliferating cells, and has been reported to modulate epithelial-mesenchymal transition during cellular differentiation. Supplied as a high-purity solid for biochemical and cellular studies.
- Potent Aurora-A kinase inhibitor (IC50 = 0.031 μM).
- Demonstrated cellular activity in multiple cancer cell lines (MCF7 IC50 1.6 μM; COLO 205 IC50 2.9 μM; HCT-116 IC50 7.8 μM).
- High purity (98.0%).
- Molecular weight 317.34; formula C18H15N5O.
- Supplied as a brown to gray solid; recommended solvent DMSO (≥ 11.11 mg/mL).
- Store solid at 4°C protected from light; in solution store at -80°C for long-term stability.
Medchemexpress LLC 3-Methylpyrazole | 1453-58-3 | 99.54% | C4H6N2 | 100 G
3-Methylpyrazole is utilized as a nitrification inhibitor to impede the nitrification process in soil, and has been shown to inhibit the metabolism of MAM by rat liver microsomes. For optimal stability, store the pure form at -20°C for 3 years or 4°C for 2 years. If in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Purity of 99.54%
- Molecular weight of 82.11
- Appears solid below 36.5°C and liquid above 36.5°C
- Color is light yellow to reddish brown
- Solubility in H₂O of 25 mg/mL (304.48 mM), requiring ultrasonic
- Solubility in PBS of 50 mg/mL (608.97 mM), forming a clear solution and requiring ultrasonic
- Inhibits the metabolism of MAM by rat liver microsomes
Medchemexpress LLC ABAT Human His SU 50ug
Recombinant human ABAT (γ-aminobutyrate aminotransferase) produced in E. coli and supplied as a lyophilized powder. The protein includes N-terminal SUMO and 10xHis tags plus a C-terminal Myc tag, is approximately 69 kDa, and is >90% pure by reducing SDS-PAGE. Formulated from PBS with 6% trehalose (pH 7.4), it is intended for biochemical and cellular research on GABA metabolism and mitochondrial function; store frozen and follow reconstitution stability guidelines.
- Expressed in E. coli with SUMO, 10xHis, and Myc tags for purification and detection.
- High purity (>90%) suitable for biochemical assays.
- Lyophilized formulation with trehalose for improved stability.
- Approximate molecular weight 69 kDa for experimental planning.
- Stable short term at 4°C after reconstitution; long-term storage at -20°C/-80°C when aliquoted.
Medchemexpress LLC 3-Nitropyrazole | 26621-44-3 | 113.08 | 100 G
3-Nitropyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds. The nitro group of 3-Nitropyrazole readily undergoes nucleophilic substitution reactions.
- Used as a biological material or organic compound
- Nitrogen-containing heterocyclic compound
- Can be used in the synthesis of other active compounds
- Nitro group readily undergoes nucleophilic substitution reactions
- Appearance: White to light yellow solid
- Purity: 99.98%
- Molecular weight: 113.08
- Storage: Powder at -20°C for 3 years; 4°C for 2 years; in solvent at -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC RecO E.coli His-SU 5ug
Recombinant RecO protein from Escherichia coli expressed with an N-terminal His-SUMO affinity tag, supplied lyophilized for biochemical and molecular biology studies of DNA recombination and repair. The product is formulated for stability and quality and is intended for binding, enzymology, and structural assays after reconstitution.
- Contains an N-terminal His-SUMO affinity tag for straightforward purification and detection.
- Purified to greater than 95% as determined by reducing SDS-PAGE.
- Approximate molecular weight 43.4 kDa, suitable for biochemical characterization.
- Lyophilized from 20 mM Tris-HCl, 0.5 M NaCl, 6% trehalose, pH 8.0, to enhance stability.
- Recommended storage at -20°C or -80°C; stable at 4°C for one week after reconstitution.
- Available in small, research-friendly sizes to facilitate assay optimization.
Medchemexpress LLC STK11 Human His-SU 50ug
STK11 Protein, Human (His-SUMO) is a recombinant human serine/threonine kinase (LKB1) expressed in E. coli and supplied lyophilized for research applications. The protein includes N-terminal SUMO and 6xHis tags to facilitate purification and detection, covers residues M1-C430, and is purified to greater than 90% as determined by reducing SDS-PAGE. It is provided in a stabilizing formulation and should be stored frozen for long-term stability.
- Recombinant human serine/threonine kinase covering residues M1-C430.
- N-terminal SUMO and 6xHis tags for purification and detection.
- Expressed in E. coli and purified to greater than 90% purity by reducing SDS-PAGE.
- Supplied lyophilized in a stabilizing buffer for storage and transport.
- Stable when stored at -20°C to -80°C; reconstituted material is stable short term at 4°C.
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC GFRAL Human His-SU 50ug
Recombinant human GFRAL protein comprising residues S19-E351 with an N-terminal His-SUMO fusion, expressed in E. coli and supplied as purified research-grade material. It is intended for biochemical and cell biology studies that require the extracellular/receptor fragment of GFRAL, and includes recommended storage and handling instructions to preserve integrity and activity.
- Sequence corresponds to UniProt Q6UXV0, residues S19-E351.
- N-terminal His and SUMO fusion tags for purification and stability.
- Expressed in E. coli and purified to 93.0% as determined by reducing SDS-PAGE.
- Typical supplied quantity: 50 μg (lyophilized).
- Storage: store at -20°C for long term; after reconstitution stable at 4°C for 1 week; aliquot and freeze at -20°C or -80°C for extended storage.
- Suitable for biochemical assays, binding studies, and cell-based experiments.
- Provided with a certificate of analysis for lot-specific quality assurance.