Thiazoles
Medchemexpress LLC Methyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)benzoate | 179003-02-2 | 279.34 | 250 MG
Methyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)benzoate is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only and should be handled by suitably qualified, experienced personnel in appropriately equipped facilities.
- Used as a drug intermediate.
- Suitable for synthesis of various active compounds.
- Identified for laboratory chemical use.
- Intended for manufacture of substances.
- For research use only.
![Medchemexpress LLC (R)-phenyl (5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)carbamate | 2135871-21-3 | 435.43 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403321-logo.png-250.jpg){kind=logo}
Medchemexpress LLC (R)-phenyl (5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)carbamate | 2135871-21-3 | 435.43 | 25 MG
(R)-phenyl (5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)carbamate is a chemical compound supplied by MedChemExpress for research use. It is intended for laboratory chemicals and the manufacture of substances by experienced personnel.
- For research use only
- Suitable for manufacturing substances
- Intended for experienced personnel
Medchemexpress LLC 93-O17S | 2227008-67-3 | C44H83N3O4S2 | 25 MG
93-O17S is an ionizable lipid involved in the construction of Lipid Nanoparticles (LNP) and can achieve mRNA delivery to the spleen. This product is for research use only.
- Ionizable lipid
- Involved in the construction of lipid nanoparticles (LNP)
- Achieves mRNA delivery to the spleen
- Delivers luciferase mRNA to the spleen of mice
- Purity: 98.0%
- Appearance: Oil
- Color: Light yellow to yellow
- Soluble in DMSO and ethanol
Medchemexpress LLC 5-Azidopentanoic acid | 79583-98-5 | 99.8% | 100 MG
5-Azidopentanoic acid, also known as 5-Azidovaleric acid, is an organic acid that can be used in click chemistry reactions. It is intended for research use only.
- Used in click chemistry reactions
- Suitable as a biochemical assay reagent
- For research applications
Medchemexpress LLC Met C-Met Antibody 100uL | 100uL
Met (C-Met) Antibody (YA5930) is a Rabbit-derived and non-conjugated IgG monoclonal antibody targeting to Met (C-Met)
Medchemexpress LLC GAL-02-221 | 2409538-70-9 | 99.9% | 1016.67 | 10 MG
GAL-02-221 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. It can potently degrade BRD4 in HER2 positive and negative breast cancer cell lines.
- Potently degrades BRD4
- Degrades BRD4 in HER2 positive and negative breast cancer cell lines
- Connected by ligands for von Hippel-Lindau and BRD4
- Shows antiproliferative activity against human 22Rv1, L02, MCF7, and MDA-MB-231 cells
Medchemexpress LLC L-Methionine, 1,1-dimethylethyl ester, hydrochloride (1:1) | 91183-71-0 | ≥98.0% | 241.78 | 1 G
H-Met-OtBu.HCl is a methionine derivative primarily used for research purposes. This compound is not intended for patient use. Amino acids and their derivatives, including H-Met-OtBu.HCl, are recognized as beneficial ergogenic dietary substances. They are commercially utilized as supplements to support physical, mental, and physiological activities by influencing anabolic hormone secretion, providing fuel during exercise, enhancing mental performance under stress, and preventing exercise-induced muscle damage.
- Influences anabolic hormone secretion
- Provides fuel during exercise
- Enhances mental performance during stress
- Prevents exercise-induced muscle damage
Apexbio Technology LLC ET SSB Protein 100ug
ET SSB Protein is a recombinant protein that selectively binds to single-stranded DNA (ssDNA) It is designed to stabilize unfolded DNA regions and prevent strand reassociation or nuclease degradation ET SSB Protein exerts its biological activity primarily by binding ssDNA maintaining DNA in a single-stranded state and withstanding incubation at temperatures up to 95 C Based on these properties ET SSB Protein holds research potential in PCR and q-PCR assay optimization enhancement of DNA polymerase performance stabilization and labeling of ssDNA facilitation of reverse transcriptase efficiency in RT-PCR and sequencing protocols involving strong secondary structures
Medchemexpress LLC N-Methylindan-2-amine hydrochloride | 10408-85-2 | 99.9% | 183.68 | 1 G
N-Methylindan-2-amine hydrochloride (compound 3b) is an N-alkylated congener of phenylethylamine that increases hot plate reaction time in mice without inducing dopaminergic effects. It can be used to study central noradrenergic mechanisms.
- Increases hot plate reaction time in mice without inducing dopaminergic effects.
- Can be used to study central noradrenergic mechanisms.
- For research use only.
Medchemexpress LLC JH-VIII-157-02 | 1639422-97-1 | 99.0% | 465.55 | 100 MG
JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It exhibits an IC50 of 2 nM for EML4-ALK G1202R in cells and potently inhibits various other EML4-ALK mutants and wild type (e.g., EML4-ALKwt, EAC1156Y, EAF1174L, EAS1206Y with IC50s of 2-196 nM). It shows selectivity at other kinases like IRAK1, CLK4, RET, and IRAK 4. JH-VIII-157-02 demonstrates inhibitory growth against cancer cell lines like H3122 and DFCI76 (EC50s of 5 nM and 19 nM). It also has good oral bioavailability and penetrates the CNS in mice.
- Structural analogue of alectinib
- Acts as an ALK inhibitor
- Shows potent inhibition of EML4-ALK G1202R mutant (IC50 of 2 nM)
- Potently inhibits other EML4-ALK mutants and wild type
- Exhibits selectivity at several other kinases
- Inhibits growth of cancer cell lines
- Good oral bioavailability in mice
- Penetrates the CNS of mice
Medchemexpress LLC 2-Phenyl-2-(2-pyridyl)acetonitrile | 5005-36-7 | 100.0% | 194.23 | 500 MG
2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396, metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion.
- Appearance: Off-white to light brown solid
- Powder storage at -20°C for 3 years or 4°C for 2 years
- Solvent storage at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO (100 mg/mL)
- Documentation such as data sheet, COA, SDS, handling instructions, HNMR, and LCMS are available
Medchemexpress LLC 4-Thiazolecarboxylic acid | 3973-08-8 | 99.97% | C4H3NO2S | 10 G
4-Thiazolecarboxylic acid (Compound 1e) is an intermediate used in the synthesis of MGL-IN-2. MGL-IN-2 inhibits wild-type MGL enzyme activity with an IC50 of 0.0121 μM. This compound is suitable for research into metabolic diseases, acting as a biochemical assay reagent and drug intermediate.
- An intermediate compound.
- Used in the synthesis of MGL-IN-2.
- Applicable in metabolic disease research.
- Functions as a biochemical assay reagent.
- Serves as a drug intermediate.
AdipoGen Thiazole Orange Solution
Chemical. CAS 107091-89-4. Formula C26H24N2O3S2. MW 476.61. Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry. Spectral data lambdaex=509nm, lambdaem=530nm in 0.1M phosphate pH 7.0 bound to dsDNA.
Medchemexpress LLC Cyhalofop-butyl | 122008-85-9 | 98.7% | 50 MG
Cyhalofop-butyl is a post-emergence herbicide that inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis.
- Purity of 98.7%
- Appears as a white to off-white solid
- Molecular weight of 357.38
- Chemical formula C20H20FNO4
- Ships at room temperature in continental US
- Store at 4°C, protected from light
- When in solvent, store at -80°C for up to 6 months or -20°C for 1 month, protected from light
- Soluble in DMSO at 250 mg/mL