Thiazoles

Organic heterocyclic compounds that consist of an azole with both sulfur and nitrogen atoms; includes compounds that are derived from thiazoles.

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1,306 – 1,320 of 2,393 results

1,306

Medchemexpress LLC 2 4-Dimethylthiazole | 1G

2 4-Dimethylthiazole | 1G

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1,307

TARGETMOL CHEMICALS INC ML-298 10MG

Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM). Purity 99.7%

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1,308

Medchemexpress LLC (2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone | 141627-42-1 | 99.6% | C20H19NO5 | 25 G

(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone is a drug intermediate for the synthesis of various active compounds. It is for research use only.

Used as a drug intermediate for active compound synthesis
Molecular weight: 353.37
Chemical formula: C20H19NO5
Appearance: Solid, yellow to brown
Shipping: Room temperature in continental US
Storage (powder): -20°C for 3 years, 4°C for 2 years
Storage (in solvent): -80°C for 6 months, -20°C for 1 month

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1,309

Apexbio Technology LLC Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] 5mg

Cytochrome P450 CYP1B1 190-198 is a tumor-associated antigen peptide derived from CYP1B1 It is designed to induce HLA-A2-restricted T-cell responses against the CYP1B1(190-198) epitope thereby promoting tumor-specific cytotoxic immune responses Cytochrome P450 CYP1B1 190-198 exerts its biological activity primarily through antigen-specific activation of CD8 T cells In HLA-A2 transgenic mouse models this peptide delivered via plasmid DNA and poly(lactide-co-glycolide) microparticles demonstrates the ability to elicit CYP1B1 peptide-specific T-cell immunity Based on these pharmacological properties Cytochrome P450 CYP1B1 190-198 holds research potential in cancer immunotherapy and studies of tumor-specific cytotoxic T-cell responses

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1,310

eMolecules 344361-90-6 | ETHYL 4-METHYL-2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBOXYLATE | AstaTech | MFCD19442787 | 228.270 | C9H12N2O3S | 95.000 | CCOC(=O)c1c(C)nc(SC)[nH]c1=O | 1g | 384830780

ETHYL 4-METHYL-2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBOXYLATE | AstaTech | 344361-90-6 | MFCD19442787 | 228.270 | C9H12N2O3S | 95.000 | CCOC(=O)c1c(C)nc(SC)[nH]c1=O | 1g | 384830780

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1,311

Medchemexpress LLC BAY-298 | 2471978-97-7 | 99.9% | 10 MM * 1 ML

BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It demonstrates potent activity against human, rat, and cynomolgus monkey LH receptors, effectively reducing sex hormone levels. It is supplied as a 10 MM solution in DMSO.

Orally active and selective LH-R antagonist
Reduces sex hormone levels
Potent inhibitory activity against human, rat, and cynomolgus monkey LH receptors
Inhibits human ERG in HEK293 cells
Lowers serum estradiol levels in proestrus female rats

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1,312

Medchemexpress LLC Imidazo[1,2-a]pyrazine, 8-(3,6-dihydro-2H-pyran-4-yl)-2-phenyl-6-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- | 3023925-68-7 | C25H26N6O | 50 MG

YL-939 is a potent ferroptosis inhibitor that targets the PHB2/ferritin/iron axis. It efficiently protects cells from ferroptosis and has shown to ameliorate liver damage in an Acetaminophen (APAP)-induced acute liver injury model.

Potent ferroptosis inhibitor
Targets the PHB2/ferritin/iron axis
Protects cells from ferroptosis
Reduces ROS levels in cytosolic and membrane lipids
Inhibits ferritinophagy by improving ferritin protein expression
Ameliorates liver damage in APAP-induced acute liver injury models
High purity of 99.03%
Solid appearance, off-white to light yellow color

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1,313

Selleck Chemical LLC (R)-Nepicastat HCl S4926-10mg

(R)-Nepicastat HCl (RS-25560-198) the R-enantiomer of Nepicastat HCl is a potent and selective inhibitor with IC50 of 25 1 nM and 18 3 nM for bovine and human dopamine- -hydroxylase with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors

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1,314

Medchemexpress LLC YL-939 | 3023925-68-7 | 99.0% | 426.51 g/mol | C25H26N6O | 10 MG

YL-939 is a small-molecule ferroptosis inhibitor that prevents iron-dependent cell death by modulating the PHB2/ferritin/iron axis. It has been characterized as a non-classical ferroptosis inhibitor with demonstrated protective activity in cellular assays.

Inhibits ferroptosis via the PHB2/ferritin/iron axis.
Demonstrated cellular activity in vitro against ferroptotic insults.
High chemical purity (~99.0%) and defined physical properties.
Off-white to light-yellow solid, molecular weight 426.51 g/mol.
CAS number 3023925-68-7 for unambiguous identification.
Soluble in DMSO (100 mg/mL) and amenable to in vivo formulations.
Store as powder at -20°C; limited stability in solution.

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1,315

Medchemexpress LLC N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-benzamide | 2244678-29-1 | 98.4% | 1 ML

TH-257 is a potent, selective allosteric inhibitor of LIM kinase 1 and LIM kinase 2 used as a chemical probe in cell biology research. It is supplied as a 10 mM solution in DMSO (1 mL vial), with typical purity of 98.36% and a molecular weight of 422.54 g/mol.

Potent inhibition of LIMK1 and LIMK2 (IC50 84 nM and 39 nM).
Allosteric mode of action with high selectivity against the kinome.
Provided as a ready-to-use 10 mM solution in DMSO for in vitro studies.
High purity suitable for research applications.
Molecular formula C24H26N2O3S and molecular weight 422.54 g/mol.

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1,316

Medchemexpress LLC JH-VIII-157-02 | 1639422-97-1 | 99.0% | 465.55 | 10 MG

JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It demonstrates potent inhibitory activity against various EML4-ALK variants, including those with resistance mutations, and shows selectivity against other kinases. This compound inhibits the growth of several cancer cell lines and exhibits good oral bioavailability, with the ability to penetrate the central nervous system in mice.

Potent inhibitor of EML4-ALK variants, including G1202R resistance mutation
Selective against various other kinases such as IRAK1, CLK4, and RET
Inhibits the growth of cancer cell lines like H3122 and DFCI76
Good oral bioavailability in mice
Penetrates the central nervous system in mice

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1,317

Medchemexpress LLC Blue Tetrazolium | 1871-22-3 | MFCD00040933 | 99.8% | 100 MG

Blue Tetrazolium is a blue dye used in microbial research that can be reduced into blue tetrazolium formazan (BTF). It acts as a substrate to determine the activity of succinate dehydrogenase (SDH) in yeast strains. BTF can be extracted from cells using DMSO, and its absorption spectrum can be analyzed with a broad wavelength range of 480-600 nm, and a maximal absorbance at 540 nm.

Used as a blue dye in microbial research.
Reducible to blue tetrazolium formazan (BTF).
Determines succinate dehydrogenase (SDH) activity in yeast strains.
Absorption spectrum of BTF shows maximal absorbance at 540 nm.
Functions as a novel corrosion inhibitor for cold-rolled steel in hydrochloric acid solutions.

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1,318

Medchemexpress LLC Tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | 99.97% | 278.36 | 50 G

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a drug intermediate used for the synthesis of various active compounds. It is for research use only and not sold to patients.

Drug intermediate
For synthesis of various active compounds

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1,319

eMolecules 1251929-90-4 | 2-hydroxy-2-(4-methylthiazol-2-yl)propanehydrazide | 250mg

Pharmablock | O3-tert-butyl O8-methyl 3-azabicyclo[3.2.1]octane-38-dicarboxylate | 25mg | 590288775 | PBLG0009 | 1403766-87-9 | MFCD23106312 | 269.341 | C14H23NO4

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1,320

eMolecules 71574-33-9 | 4,5-Dimethylthiazol-2-amine hydrochloride | Oakwood Chemical | MFCD00012711 | 164.650 | C5H9ClN2S | 98.000 | Cl.Cc1nc(N)sc1C | 1g | 537714270

4,5-Dimethylthiazol-2-amine hydrochloride | Oakwood Chemical | 71574-33-9 | MFCD00012711 | 164.650 | C5H9ClN2S | 98.000 | Cl.Cc1nc(N)sc1C | 1g | 537714270

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Thiazoles

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Medchemexpress LLC 2 4-Dimethylthiazole | 1G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC ML-298 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone | 141627-42-1 | 99.6% | C20H19NO5 | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BAY-298 | 2471978-97-7 | 99.9% | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Imidazo[1,2-a]pyrazine, 8-(3,6-dihydro-2H-pyran-4-yl)-2-phenyl-6-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- | 3023925-68-7 | C25H26N6O | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC (R)-Nepicastat HCl S4926-10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC YL-939 | 3023925-68-7 | 99.0% | 426.51 g/mol | C25H26N6O | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-benzamide | 2244678-29-1 | 98.4% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC JH-VIII-157-02 | 1639422-97-1 | 99.0% | 465.55 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Blue Tetrazolium | 1871-22-3 | MFCD00040933 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | 99.97% | 278.36 | 50 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More