2-Isobutyl-3-methoxypyrazine-d3 is the deuterium-labeled analogue of 2-isobutyl-3-methoxypyrazine, an aroma constituent in grapes, wines, green pepper, and asparagus. The labeled material (d3) is provided as a reference standard for analytical and research use, including isotope-dilution assays, method development, and trace-level quantitation.