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Filtered Search Results
Medchemexpress LLC 2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-a,a-dimethyl- | 1204975-42-7 | 98.92% | 432.56 | 50 MG
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LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively. It inhibits Hedgehog (Hh) signaling in a human cell line (HEPM) and shows a tendency to preferentially inhibit Gli1 rather than Ptch1 mRNA. It is efficacious in decreasing Gli1 mRNA by approximately 70% to 80%.
- Second-generation inhibitor of smoothened (Smo).
- IC50s of 2 nM (human smo) and 4 nM (mouse smo).
- Inhibits Hedgehog (Hh) signaling in a human cell line.
- Efficacious in decreasing Gli1 mRNA by approximately 70% to 80%.
- Shows a tendency to preferentially inhibit Gli1 over Ptch1 mRNA.
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Alkali Scientific Tobramycin Sulfate, 100 Mg
Tobramycin Sulfate is an aminoglycoside antibiotic used for treating severe bacterial infections caused by gram-negative bacteria. Available in powder form, it is commonly used for the treatment of respiratory tract infections, urinary tract infections, and other life-threatening bacterial infections. The 100mg vial provides a concentrated dose to ensure the antibiotic's efficacy against resistant organisms. Tobramycin works by inhibiting bacterial protein synthesis, making it effective for treating infections that do not respond to other antibiotics. The product is commonly used in hospitals and clinical settings for intravenous administration.
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eMolecules 1265166-14-0 | Medchem Express | Antifungal agent 1 | 5mg | 446257586 | HY-102025 | 352.77 | C19H13ClN2O3
Medchem Express | Rizatriptan (benzoate) | 10mg | 518571254 | HY-B0206 | 145202-66-0 | MFCD00866224 | 391.475 | C22H25N5O2
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Chem-Impex International, Inc. Colistin methanesulfonate sodium salt | 8068-28-8 | MFCD31707668 | 100MU
Colistin methanesulfonate sodium salt, 8068-28-8, MFCD31707668, 100MU
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Medchemexpress LLC Natamycin (standard) | 7681-93-8 | 99.5% | 50 MG
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Natamycin (Standard) is an analytical standard, also known as Pimaricin. This macrolide antibiotic agent is produced by several Streptomyces strains. It inhibits fungal growth by preventing amino acid and glucose transport across the plasma membrane, making it suitable for various research and analytical applications.
- Intended for research and analytical applications
- Inhibits fungal growth by preventing amino acid and glucose transport
- Used as a food preservative
- Functions as an antifungal agent in agriculture
- Utilized for fungal keratitis research
- Applied in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
- Serves as a reference standard assay
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Medchemexpress LLC Carmofur (HCFU) | 61422-45-5 | 99.9% | 500 MG
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Carmofur (HCFU) is a rat recombinant acid ceramidase inhibitor with an IC50 of 29 nM. It also functions as a protease inhibitor of SARS-CoV-2 main protease (Mpro), fatty acid amide hydrolase (FAAH), and N-acylethanolamine acid amidase (NAAA). This compound demonstrates anti-cancer, anti-inflammatory, and anti-virus activities, making it valuable for research into COVID-19 and acute lung injury (ALI).
- Inhibits acid ceramidase (AC) activity in human colon cancer SW403 cells.
- Inhibits SARS-CoV-2 activity in Vero E6 cells.
- Acts as an inhibitor of FAAH and NAAA activities in HEK293 cells.
- Shows anti-inflammatory effects in Raw264.7 cells by reducing pro-inflammatory cytokines.
- Improves LPS-induced inflammatory responses and promotes resolution of lung injury in acute lung injury (ALI) mice models.
- Inhibits AC activity in various tissues in male Swiss Webster mice.
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Medchemexpress LLC Cl-amidine (hydrochloride) | 1373232-26-8 | 99.4% | 347.25 g·mol⁻¹ | C14H20Cl2N4O2 | 100 MG
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Cl-amidine hydrochloride is the hydrochloride salt of Cl-amidine, a peptidylarginine deiminase (PAD) inhibitor used in biochemical and cellular research. It is supplied as a white to light yellow solid with batch-specific high purity and is applied to inhibit PAD-mediated protein citrullination in vitro and in vivo studies.
- High purity suitable for biochemical and cellular research.
- Pan-PAD inhibition activity for PAD1, PAD3, and PAD4 studies.
- White to light yellow solid for stable storage and handling.
- Molecular weight 347.25 g·mol⁻¹ for accurate dosing.
- Recommended storage at -20°C under nitrogen to preserve stability.
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Medchemexpress LLC (1R,2R)-2-PCCA hydrochloride | 1609563-71-4 | 98.1% | 528.56 g/mol | C30H39Cl2N3O | 5 MG
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(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA and a potent small-molecule agonist of the GPR88 receptor for research applications. It shows high potency in biochemical assays and measurable cellular activity, supplied as a solid hydrochloride salt with defined purity and solubility for in vitro and in vivo use.
- Potent GPR88 receptor agonist with EC50 3 nM in cell-free assay.
- Demonstrates cellular activity with EC50 603 nM in cell-based assays.
- High purity solid (98.08%).
- Soluble in DMSO (50 mg/mL) and compatible with stated in vivo formulations.
- Light yellow to khaki solid; store at 4°C under nitrogen; solutions stable at -80°C for six months.
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Medchemexpress LLC HY-112473 100mg Medchemexpress, NAV-2729 CAS:419547-11-8 Purity:98%
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Medchemexpress,HY-112473 100mg NAV-2729 CAS:419547-11-8 Formula:C25H17ClN4O3 NAV-2729 is a dual Arf1/Arf6 activation inhibitor. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC D-Cl-amidine hydrochloride | 2985338-61-0 | 99.9% | 347.24 g/mol | C14H20Cl2N4O2 | 100 MG
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D-Cl-amidine hydrochloride is a research-grade small-molecule inhibitor provided as the hydrochloride salt and intended for in vitro and preclinical studies. It is supplied as a solid powder with high reported purity and should be handled and stored under recommended conditions to preserve stability.
- Selective inhibitor of protein arginine deiminase 1 (PAD1).
- Hydrochloride salt, solid form.
- High purity (99.9%).
- White to light yellow powder.
- Store at -20°C, protect from light and moisture.
- Available in research quantities such as 100 MG.
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Medchemexpress LLC A 438079 hydrochloride | 899431-18-6 | C13H10Cl3N5 | 100 MG
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A 438079 hydrochloride is a potent and selective antagonist of the P2X7 receptor, with a pIC50 of 6.9. It blocks BzATP-evoked changes in intracellular calcium concentrations with an IC50 of 321 nM in 1321N1 cells expressing rat P2X7 receptors. This compound shows selectivity for the P2X7 receptor at concentrations up to 100 μM and has demonstrated neuroprotective effects in vivo.
- P2X7 receptor antagonist
- Reduces noxious and innocuous evoked activity of spinal neurons
- Raises withdrawal thresholds in neuropathic models
- Reduces seizure severity and neuronal death
- White to off-white solid appearance
- High purity of 99.99%
- Soluble in DMSO and H2O
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Medchemexpress LLC HY-100034 25mg Medchemexpress, NSC 663284 CAS:383907-43-5 Purity:>98%
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Medchemexpress, HY-100034 25mg NSC 663284 CAS:383907-43-5 NSC 663284 is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC 50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 848249-10-5 | Medchem Express | HS-243 | 5mg | 721310160 | HY-134911 | 324.34 | C17H16N4O3
Medchem Express | HS-243 | 5mg | 721310160 | HY-134911 | 848249-10-5 | 324.340 | C17H16N4O3
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eMolecules 76326-31-3 | Medchem Express | DL-AP5 | 5mg | 736629904 | HY-100714 | MFCD00010515 | 197.127 | C5H12NO5P
Medchem Express | DL-AP5 | 5mg | 736629904 | HY-100714 | 76326-31-3 | MFCD00010515 | 197.127 | C5H12NO5P
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Medchemexpress LLC c-Fms-IN-10 | 1527517-50-5 | 98.6% | 429.5 g/mol | C22H19N7OS | 50MG
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c-Fms-IN-10 is a potent small-molecule inhibitor of the Colony Stimulating Factor 1 Receptor (CSF-1R, also called c-Fms), developed as a thieno[3,2-d]pyrimidine derivative with reported anti-tumor activity and an in vitro IC50 of 2 nM. It is supplied as a solid and as a 10 mM solution in DMSO for in vitro use, and has high purity and well-defined storage recommendations for both powder and solution forms.
- Potent inhibitor of CSF-1R with IC50 = 2 nM.
- Thieno[3,2-d]pyrimidine derivative with kinase inhibitory activity.
- Available as solid solids and as a 10 mM DMSO solution for in vitro studies.
- Soluble in DMSO at 10 mg/mL using ultrasonic warming to 60°C.
- High purity suitable for research applications.
- Defined storage stability for powder and solution forms.
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