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Filtered Search Results
Medchemexpress LLC ICA-105665 (PF-04895162) | 2694728-63-5 | 99.9% | 355.34 | C19H15F2N3O2 | 5MG
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ICA-105665 is a small-molecule research compound that acts as an orally active neuronal Kv7 potassium channel opener selective for Kv7.2/7.3 and Kv7.3/7.5. It is provided for laboratory research in milligram-scale quantities and is available as a solid or as a 10 mM solution in DMSO. Molecular formula C19H15F2N3O2; molecular weight 355.34.
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eMolecules 871361-88-5 | Medchem Express | SC66 | 5mg | 446270447 | HY-19832 | MFCD05025493 | 276.339 | C18H16N2O
Medchem Express | SC66 | 5mg | 446270447 | HY-19832 | 871361-88-5 | MFCD05025493 | 276.339 | C18H16N2O
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eMolecules 1005883-72-6 | Medchem Express | Z433927330 | 5mg | 482204282 | HY-126074 | 364.405 | C20H20N4O3
Ambeed | (3aR5R6S7R7aR)-2-(Ethylamino)-5-(hydroxymethyl)-5677a-tetrahydro-3aH-pyrano[32-d]thiazole-67-diol | 1mg | 534567940 | A333018 | 1009816-48-1 | MFCD15144964 | 248.300 | C9H16N2O4S
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Medchemexpress LLC CDK9-IN-13 | 2768712-71-4 | 99.9% | 461.60 | 50 MG
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CDK9-IN-13 is a potent and selective CDK9 inhibitor, demonstrating an IC50 of <3 nM. It also shows inhibitory activity against CDK1, CDK2, CDK7, and CDK12. The compound exhibits short half-lives in rodents and is intended for research use only.
- Potent and selective CDK9 inhibitor
- Inhibits CDK1, CDK2, CDK7, and CDK12
- Suitable for research use only
- Short half-lives in rodents
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO (2.5 mg/mL)
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Medchemexpress LLC Biotin-PEG6-thalidomide | 2144775-48-2 | MFCD31561114 | 98.3% | C37H53N5O12S | 10MG
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Biotin-PEG6-thalidomide is a biotinylated polyethylene glycol (PEG6)-linked thalidomide derivative used as a PROTAC linker and cereblon (CRBN) affinity probe for targeted protein degradation research. It provides a hydrophilic spacer and a biotin handle to facilitate synthesis, biochemical assays, and affinity-based capture of protein complexes. Supplied for research use only.
- Provides a PEG6 spacer to increase solubility and flexibility
- Contains a thalidomide-derived moiety for cereblon binding
- Includes a biotin tag for affinity capture and pull-down assays
- Suitable for PROTAC synthesis and CRBN-binding studies
- Compatible with common organic solvents and assay conditions
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Medchemexpress LLC Lobeline (hydrochloride) | 134-63-4 | 99.9% | 50 MG
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Lobeline hydrochloride is a brain-penetrant nicotinic receptor agonist that increases dopamine release by inhibiting dopamine uptake into synaptic vesicles and altering presynaptic dopamine storage. It is effective in smoking cessation and is intended for research use only.
- Brain-penetrant nicotinic receptor agonist
- Increases dopamine release
- Inhibits dopamine uptake into synaptosomes and vesicles
- Effective in smoking cessation studies
- Decreases d-methamphetamine self-administration in rat models
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Medchemexpress LLC HY-100527 5mg Medchemexpress, AN2718 CAS:174672-06-1 Purity:>98%
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Medchemexpress, HY-100527 5mg AN2718 CAS:174672-06-1 AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Benzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate | 189349-50-6 | MFCD05664727 | 100.0% | 522.60 g/mol | C27H34N6O5 | 10 MG
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L-765314 is a research compound that selectively antagonizes the α1B adrenergic receptor. It has reported inhibition constants in the low nanomolar range for rat and human receptors and is typically supplied as a solid for laboratory pharmacology and receptor characterization studies.
- Potent α1B receptor antagonist with low-nanomolar affinity.
- Selectivity suitable for subtype-specific pharmacology studies.
- Reported Ki values: 5.4 nM (rat) and 2.0 nM (human).
- Solid powder form allows flexible storage and formulation.
- Commonly used for receptor binding, signaling, and cardiovascular research.
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Selleck Chemical LLC Levofloxacin hydrate S4604-20mg
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Levofloxacin (Levaquin Tavanic Quixin Iquix Cravit) is a broad-spectrum third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity It acts by inhibiting DNA gyrase (bacterial topoisomerase II)
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Enzo Life Sciences Staurosporine, (250µg), CAS Number: 62996-74-1
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Apoptosis inducer. Protein kinase inhibitor. Model apoptosis inducer. Potent cell-permeable inhibitor of a variety of protein kinases, e.g. protein kinase C (PKC), CDK1/cyclin B (IC50~5nM), CDK2/cyclin A (IC50=7nM), CDK4/cyclin D (IC50=3-10µM), CDK5/p25 (IC50=4nM), GSK-3β (IC50=15nM), Pim-1 kinase (IC50=10nM).Binds do the ATP binding domain. Did not inhibit PKC-ζ. At 1µM induced apoptosis in CHO cells. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine. Alternative Name: Antibiotic AM-2282. Formula: C28H26N4O3. MW: 466.5. CAS Number: 62996-74-1. MI: 14: 8802. Purity: ≥99% (HPLC). Appearance: Off-white to green powder. Solubility: Soluble in ethyl acetate, DMSO (25mg/ml) or dimethyl formamide (25mg/ml); only slightly soluble in chloroform and methanol. Insoluble in water. Use/Stability: Stable for at least 2 years after receipt when stored +4°C. Long Term Storage: +4°C
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eMolecules 53123-88-9 | Rapamycin | AA Blocks LLC914.187 | C51H79NO13 | 0.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 25mg | 585999344
Rapamycin | AA Blocks LLC | 53123-88-9914.187 | C51H79NO13 | 0.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 25mg | 585999344
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CPC Scientific H-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2 (trifluoroacetate salt) 1MG
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Potent antagonist of PTH-related protein (1-34) in vitro and in vivo.ONE-LETTER SEQUENCE: LLHDKGKSIQDLRRRFFLHHLIAEIHTA-NH2MOLECULAR FORMULA: C153H247N49O37MOLECULAR WEIGHT:3364.95STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [115695-30-2], SYNONYMS: pTHrP (7-34) amide (human, mouse, rat), pTH-Related Protein (7-34) amide (human, mouse, rat)RESEARCH AREA: OsteoporosisREFERENCES: R.L. McKee et al., J. Bone and Mineral Res., 3, S73 (1988)
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Medchemexpress LLC Ponatinib hydrochloride (AP24534 hydrochloride) | 1114544-31-8 | 99.76% | 569.02 | 500 MG
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Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride salt of ponatinib. It is an orally active multi-targeted kinase inhibitor with IC50 values of 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src.
- Orally active multi-targeted kinase inhibitor.
- Inhibits Abl with an IC50 of 0.37 nM.
- Targets PDGFRα with an IC50 of 1.1 nM.
- Inhibits VEGFR2 with an IC50 of 1.5 nM.
- Targets FGFR1 with an IC50 of 2.2 nM.
- Inhibits Src with an IC50 of 5.4 nM.
- Reduced viability, migration, and function of human endothelial cells in vitro.
- Protects mice from lethal influenza infection by inhibiting cytokine storm in vivo.
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eMolecules 88122-99-0 | Octyl triazone | Combi-Blocks | MFCD09753106 | 823.092 | C48H66N6O6 | 97.000 | CCCCC(CC)COC(=O)c1ccc(Nc2nc(Nc3ccc(cc3)C(=O)OCC(CC)CCCC)nc(Nc3ccc(cc3)C(=O)OCC(CC)CCCC)n2)cc1 | 25g | 528670228
Octyl triazone | Combi-Blocks | 88122-99-0 | MFCD09753106 | 823.092 | C48H66N6O6 | 97.000 | CCCCC(CC)COC(=O)c1ccc(Nc2nc(Nc3ccc(cc3)C(=O)OCC(CC)CCCC)nc(Nc3ccc(cc3)C(=O)OCC(CC)CCCC)n2)cc1 | 25g | 528670228
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Medchemexpress LLC Y15 (FAK inhibitor 14) | 4506-66-5 | 98.0% | 284.01 g/mol | C6H14Cl4N4 | 100MG
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Y15 (FAK Inhibitor 14) is a small-molecule research compound that inhibits focal adhesion kinase (FAK) autophosphorylation, reduces cancer cell viability in vitro, and has been used to block tumor growth in preclinical studies. It is supplied as a research-grade reagent for cellular and biochemical assays.
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