Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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2,611 – 2,625 of 7,041 results

2,611

eMolecules 1784282-12-7 | Medchem Express | KHS101 hydrochloride | 5mg | 437899078 | HY-10996A | MFCD28133379 | 375.92 | C18H22ClN5S

ChemScene | tert-Butyl (124-thiadiazol-5-yl)carbamate | 1g | 536804720 | CS-0099339 | 264600-76-2 | MFCD18375242 | 201.240 | C7H11N3O2S

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2,612

Medchemexpress LLC Clarithromycin | 81103-11-9 | 99.93% | 747.95 | 500 MG

Clarithromycin has a broad spectrum of antimicrobial activity. It inhibits CYP3A4-catalyzed triazolam alpha-hydroxylation with an IC50 (Ki) value of 56 (43) μM. It significantly inhibits the hERG potassium current and affects autophagic flux by impairing the signaling pathway linking hERG1 and PI3K. It has also shown activity against Mycobacterium avium complex infection in mice.

Broad spectrum of antimicrobial activity
Inhibits CYP3A4-catalyzed triazolam alpha-hydroxylation
Significantly inhibits hERG potassium current
Affects autophagic flux by impairing the signaling pathway linking hERG1 and PI3K
Induces intracytoplasmic vacuoles in various cell lines
Triggers apoptotic cell death in colorectal cancer cells
Increases LC3-II/LC3-I ratio dose- and time-dependently
Reduced organ cell counts in animal models of Mycobacterium avium infection

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2,613

Medchemexpress LLC 1H-Pyrrole-3-carboxamide, N-[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoin | 2222635-92-7 | 99.3% | 654.69 | 100 MG

MI-389 is a PROTAC translation termination factor GSPT1 degrader. It disrupts a target that is a shared dependency in different AML and ALL cell lines, and its action is dependent on the CRL4CRBN E3 ligase.

Disrupts GSPT1 target
Action dependent on CRL4CRBN E3 ligase
Target is Cereblon
EC50 value of 21.3 nM on Kasumi 1 cells
Antiproliferative activity against human Kasumi 1 cells
Molecular formula: C35H35FN6O6
Appearance: Yellow to orange solid
Purity: 99.34%
Solubility: 66.67 mg/mL (101.83 mM) in DMSO
Storage: 4°C, stored under nitrogen
In solvent storage: -80°C for 6 months; -20°C for 1 month (stored under nitrogen)

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2,614

Medchemexpress LLC Cd80-in-3 | 486449-65-4 | MFCD32701897 | 98.0% | 323.28 g/mol | C17H10FN3O3 | 100 MG

CD80-IN-3 is a small-molecule inhibitor that blocks the CD80/CD28 interaction, showing in vitro potency (EC50 = 630 nM) and measurable binding affinity (Kd = 125 nM). It is supplied as a solid and is also available as a DMSO solution for assay use; intended for research use only.

Potent CD80 inhibitor; inhibits CD80/CD28 interaction (EC50 = 630 nM).
Measured binding affinity Kd = 125 nM.
High purity solid suitable for biochemical and cellular assays (98.0%).
Molecular weight 323.28 g/mol; molecular formula C17H10FN3O3.
CAS number 486449-65-4 for unambiguous identification.
Available in milligram quantities and solution formats for assay flexibility.

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2,615

Medchemexpress LLC Benzoic acid, 4-(6-fluoro-3,5-dihydro-3-oxo-2H-pyrazolo[4,3-c]quinolin-2-yl) | 486449-65-4 | 98.0% | 323.28 g/mol | C17H10FN3O3 | 5 MG

CD80-IN-3 is a small-molecule inhibitor of the immune co-stimulatory protein CD80 that disrupts CD80-CD28 interaction. It is reported to have an EC50 of 630 nM and a binding Kd of 125 nM, and is supplied as a high-purity solid for in vitro research applications.

Potent inhibition of CD80-CD28 interaction (EC50 630 nM; Kd 125 nM).
Well-characterized small molecule: MW 323.28, formula C17H10FN3O3.
High purity suitable for biochemical and cell-based assays.
Available in small research quantities for screening and profiling.
Stable powder with defined storage conditions for long-term retention.
Light brown to yellow solid, convenient for formulation in DMSO.

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2,616

Research Products International Corp PAROMOMYCIN SULFATE, 1GM

Paromomycin Sulfate belongs to the aminoglycoside class of antibiotics. It is primarily studied for its antibiotic properties, particularly its effectiveness against various types of bacteria and parasites.

Researchers investigate its mechanism of action, pharmacokinetics, and potential applications in treating infectious diseases.

Paromomycin is often used as a tool in molecular biology research due to its ability to inhibit protein synthesis in bacteria and parasites. It is employed in experiments involving gene expression, translation studies, and the development of antibiotic resistance mechanisms.

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2,617

Medchemexpress LLC HY-108881 1mg , Troleandomycin CAS:2751-09-9 Purity:>98%

HY-108881 1mg Troleandomycin CAS: 2751-09-9 Troleandomycin (Triacetyloleandomycin), a macrolide acrolide antibiotic, is a selective CYP3A inhibitor. Troleandomycin is an oral corticosteroid for asthma study. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,618

Research Products International Corp Cefazolin Sodium Salt, 100 Milligrams

Cefazolin Sodium Salt is a first-generation cephalosporin antibiotic. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), enzymes involved in the final stages of peptidoglycan synthesis. This interference leads to structural instability and eventual cell lysis.

Effective against a broad spectrum of bacteria, particularly Gram-positive organisms. Can be used in microbiology research and studies focusing on antibacterial agents. Its inclusion in culture media can help selectively isolate bacteria that are susceptible to this antibiotic.

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2,619

Medchemexpress LLC (E)-3-(4-chlorobenzyl)-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one | 2101739-18-6 | 99.9% | 10 MG

RAD51-IN-1 is a small-molecule inhibitor of the RAD51 recombinase, described as a derivative of B02 and used in preclinical cancer research to study homologous recombination and DNA repair pathways.

Potent RAD51 inhibitor for studying DNA repair
Molecular formula C22H16ClN3O and molecular weight 373.83
High purity suitable for biochemical assays (listed as 99.89%)
Available in multiple package sizes, including 10 MG
Yellow to orange solid, commonly supplied as a research reagent

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2,620

Medchemexpress LLC HY-N0068 100mg , Solasodine Purapuridine;Solancarpidine;Solasodin CAS:126-17-0 Purity:98%

Medchemexpress, HY-N0068 100mg Solasodine Purapuridine;Solancarpidine;Solasodin CAS:126-17-0 Formula:C27H43NO2 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,621

Apexbio Technology LLC Rifampin(Synonyms: Rifampicin, Rifaldazine, Rifadin, Rimactane, Rifoldin, Rofact, Rifamycin AMP, Riforal), 10mM (in 1mL DMSO), CAS: 13292-46-1.

Rifampin (CAS 13292-46-1) is an antibiotic belonging to the rifamycin family characterized by bactericidal activity via selective inhibition of bacterial DNA-dependent RNA polymerase This inhibition disrupts transcriptional initiation by preventing RNA synthesis leading to impaired bacterial protein biosynthesis and subsequent cell death In biomedical research rifampin serves as an essential tool for investigations into bacterial resistance mechanisms transcriptional regulation and synthetic biology studies that rely on specific transcription inhibition

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2,622

Medchemexpress LLC HY-50909 100mg , Perifosine KRX-0401;NSC 639966;D21266 CAS:157716-52-4 Purity:98%

Medchemexpress, HY-50909 100mg Perifosine KRX-0401;NSC 639966;D21266 CAS:157716-52-4 Formula:C25H52NO4P Akt Purity:98% Perifosine is an oral Akt inhibitor. All cells are sensitive to the antiproliferative properties of Perifosine with an IC 50 of ~0.6-8.9 μM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,623

Enzo Life Sciences Geldanamycin (5mg). CAS: 30562-34-6

Potent antitumor antibiotic. Inhibitor of pp60src tyrosine kinase and of c-myc gene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src, and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Capable of destabilizing several oncogene and proto-oncogene products. Potent inhibitor of the nuclear hormone receptor family. Protects against α-synuclein toxicity to dopaminergic neurons in Drosophila. Destabilizes mutant p53 protein from a number of breast, leukemic, and prostate cell lines. Inhibits basal and hypoxia-induced expression of c-Jun (IC50=75nM) and abolishes hypoxia-induced increase in c-Jun N-terminal kinase (JNK) activity. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (10mg/ml); insoluble in water. Long Term Storage: -20°C.

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2,624

Medchemexpress LLC Thiamphenicol (Standard) | 15318-45-3 | 99.6% | 50 MG

Thiamphenicol (Standard) is an analytical standard and a methyl-sulfonyl derivative of Chloramphenicol. This broad-spectrum antimicrobial antibiotic inhibits protein synthesis by binding to the 50S ribosomal subunit, providing a bacteriostatic effect against Gram-negative, Gram-positive aerobic, and anaerobic bacteria. It is intended for research and analytical applications.

Analytical standard
Methyl-sulfonyl derivative of chloramphenicol
Broad-spectrum antimicrobial activity
Inhibits bacterial protein synthesis
Effective against Gram-negative, Gram-positive aerobic, and anaerobic bacteria
Suitable for research and analytical applications

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2,625

AdipoGen Epoxomicin,Chemical. CAS: 134381-21-8

Epoxomicin, AdipoGen Life Sciences. Chemical. CAS: 134381-21-8. Formula: C28H50N4O7. MW: 554.7. Synthetic. Antibiotic. Potent anticancer compound. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome trypsin-like and caspase-like activitives (100 and 1,000-fold slower rates respectively). Anti-inflammatory. Antimicrobial and antimalarial. Anti-parasitic. Stimulates bone formation by inhibiting osteoblast proteasome activity. Induces Parkinson's-like symptoms in rats. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems. Blockade of UPS by Epoxomicin activates autophagy.

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Antibiotics

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Medchemexpress LLC Clarithromycin | 81103-11-9 | 99.93% | 747.95 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1H-Pyrrole-3-carboxamide, N-[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoin | 2222635-92-7 | 99.3% | 654.69 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cd80-in-3 | 486449-65-4 | MFCD32701897 | 98.0% | 323.28 g/mol | C17H10FN3O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Benzoic acid, 4-(6-fluoro-3,5-dihydro-3-oxo-2H-pyrazolo[4,3-c]quinolin-2-yl) | 486449-65-4 | 98.0% | 323.28 g/mol | C17H10FN3O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp PAROMOMYCIN SULFATE, 1GM Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-108881 1mg , Troleandomycin CAS:2751-09-9 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Cefazolin Sodium Salt, 100 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E)-3-(4-chlorobenzyl)-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one | 2101739-18-6 | 99.9% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N0068 100mg , Solasodine Purapuridine;Solancarpidine;Solasodin CAS:126-17-0 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-50909 100mg , Perifosine KRX-0401;NSC 639966;D21266 CAS:157716-52-4 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thiamphenicol (Standard) | 15318-45-3 | 99.6% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More