Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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2,851 – 2,865 of 7,041 results

2,851

Medchemexpress LLC HY-15142 200mg , Doxorubicin (hydrochloride) CAS:25316-40-9 Purity:>98%

HY-15142 200mg Doxorubicin (hydrochloride) CAS: 25316-40-9 Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,852

Enzo Life Sciences Leptomycin B (100µg). CAS: 87081-35-4

A potent and specific nuclear export inhibitor. Leptomycin B alkylates and inhibits CRM1/exportin 1, a protein required for nuclear export of proteins containing a nuclear export sequence (NES). In addition to antifungal and antibacterial activities, blocks the cell cycle and is a potent anti-tumor agent. At low nM concentrations, blocks the nuclear export of many proteins including HIV-1 Rev, MAPK/ERK, and NF-κB/IκB and it stabilizes the expression of p53. Other proteins that are influenced by leptomycin B are actin, c-Abl, cyclin B1, MDM2/p53, Iκb, MPF and PKA. Leptomycin B also inhibits the export and translation of many RNAs, including COX-2 and c-Fos mRNAs, by inhibiting export of ribonucleoproteins. Alternative name: LMB. Formulation: Solution in 100% ethanol. Purity: ≥96% (HPLC). Appearance: Liquid. Solubility: Soluble in methanol or 100% ethanol; insoluble in water. Unstable in DMSO. Long Term Storage: -20°C.

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2,853

U.S. Pharmacopeia Linezolid | 165800-03-3 | MFCD00937825 | 200 mg

Linezolid | Mol Wt: 337.35 | 165800-03-3 | MFCD00937825 | 200 mg

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2,854

eMolecules 3615-17-6 | N-Acetyl-D-mannosamine | MFCD09756160 | 1g

Medchem Express | Velusetrag | 5mg | 634371096 | HY-10457 | 866933-46-2 | 504.650 | C25H36N4O5S

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2,855

eMolecules 132-98-9 | Penicillin V potassium | Apollo Scientific | MFCD00051771 | 388.480 | C16H17KN2O5S | 0.000 | [K+].CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C([O-])=O | 25g | 562435273

Penicillin V potassium | Apollo Scientific | 132-98-9 | MFCD00051771 | 388.480 | C16H17KN2O5S | 0.000 | [K+].CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C([O-])=O | 25g | 562435273

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2,856

Selleck Chemical LLC Daptomycin S1373-10mM/1mL

Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms

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2,857

Selleck Chemical LLC Cyclophosphamide Monohydrate S2057-200mg

Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent it attaches the alkyl group to the guanine base of DNA shown to crosslink DNA causing strand breakage and inducing mutations Cyclophosphamide (NSC-26271) Monohydrate can be used to induce animal models of Anemia

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2,858

Selleck Chemical LLC Tanespimycin (17-AAG) S1141-1g

Tanespimycin (17-AAG CP127374 NSC-330507 KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells Tanespimycin (17-AAG) induces apoptosis necrosis autophagy and mitophagy Phase 3

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2,859

Selleck Chemical LLC Veratraldehyde (3.4-Dimethoxybenzaldehyde) S3214-500mg

Veratraldehyde (3 4-dimethoxybenzaldehyde VD VAD VAld Verapamil Related Compound E Methylvanillin) a derivative of vanillin is the chemical that is found and isolated from peppermint ginger bourbon vanilla and fruits such as raspberry Veratraldehyde is widely used as a flavorant and odorant because of its pleasant woody fragrance Veratraldehyde also acts as a redox cycle agent

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2,860

STEMCELL Technologies Puromycin (Dihydrochloride), Size: 500 mg

Puromycin is an aminonucleoside antibiotic, derived from Streptomyces alboniger, which acts as a protein synthesis inhibitor. It binds to the target ribosome site A, where it is transferred to the growing polypeptide chain causing premature chain termination (Lührmann et al.; Rodriguez-Fonseca et al.; Azzam & Algranati). A biologically inactive form is generated when puromycin is N-acetylated by puromycin-N-acetyltransferase, allowing this gene to be used as a selective resistance marker (Vara et al. 1985).CELL LINE DEVELOPMENT· Selects for cells expressing puromycin-N-acetyltransferase resistance gene as a research tool (de la Luna & Ortín; Iwaki et al.).· Useful in CRISPR/Cas9 mammalian gene editing by selecting for successful Cas9-induced knock-in with puromycin resistance gene (Park et al.). CANCER RESEARCH· Possesses anti-tumor activity when tested against numerous cell lines (Foley & Eagle).

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2,861

Research Products International Corp Mitomycin C, 5 MG

Mitomycin C is a potent antitumor antibiotic. It is derived from Streptomyces caespitosus and exhibits strong cytotoxic properties. It works by cross-linking DNA, inhibiting DNA synthesis, and inducing cell death. Mitomycin C finds applications in molecular biology and cell biology research. It is frequently employed as a DNA cross-linking agent in studies involving DNA damage and repair mechanisms.

Researchers use Mitomycin C to induce DNA adduct formation and study the cellular response to DNA damage. One notable feature of Mitomycin C is its ability to induce DNA cross-links in both dividing and non-dividing cells, making it useful for investigating cellular processes beyond actively dividing cells.

WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

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2,862

AG Scientific Inc Actinomycin D, 25 MG

Actinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria. Actinomycin D was the first antibiotic shown to have anti-cancer activity. Produced by several Streptomyces spp. Actinomycin is a clear, yellow liquid administered intravenously and most commonly used in the treatment of a variety of cancers. Actinomycin D can induce apoptosis in several cell lines such as lung and prostate cancer lines, and human blood lymphocytes.Used as a radiosensitizer in adjunct to radiotherapies since it can increase the radiosensitivity of tumor cells. In cell biology, actinomycin D is shown to have the ability to inhibit transcription.CAS Number: 50-76-0Molecular Weight: 1255.42 DaChemical Formula: C62H86N12O16Solubility: Clear orange solution at 50 mg/mL DMSO or 10 mg/mL MeOHStorage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.

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2,863

AG Scientific Inc Blasticidin S HCl Sol, 5X2 ML

Blasticidin S HCL is an antibiotic that demonstrates a strong inhibitory effect on protein synthesis in eukaryotic and prokaryotic cells. Blasticidin causes tRNA to bond more strongly to the P site of the large ribosomal subunit while simultaneously deforming the tRNA, thus inhibiting proper translation. The ultimate result of this process is a significant suppression of the hydrolysis of peptidyl-tRNA along with inhibition of peptide bond formation. Isolated from Streptomyces griseochromogenes.CAS Number: 3513-03-9Molecular Weight: 458.9 DaChemical Formula: C17H26N8O5HClSolubility: Soluble in water. Clear and faint yellow solution at 5 mg/ml in water. Insoluble in organic solvents.Storage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.

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2,864

Enzo Life Sciences Puromycin Aminonucleoside (50mg). CAS: 58-60-6

A puromycin analog which does not inhibit protein synthesis or induce apoptosis. It is a glomerular epithelial cell toxin which may be used to induce nephropathy in laboratory animals. Alternative name: 3'-Amino-3'-Deoxy-N,N-dimethyladenosine. Purity: ≥98% (TLC). Solubility: Soluble in water (10mg/ml). Long Term Storage: -20°C.

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2,865

Enzo Life Sciences HDAC assay buffer II (20ml)

50 mM Tris/Cl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, 1 mg/ml BSA. Long Term Storage: -20°C.

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Antibiotics

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Medchemexpress LLC HY-15142 200mg , Doxorubicin (hydrochloride) CAS:25316-40-9 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Mitomycin C, 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-15142 200mg , Doxorubicin (hydrochloride) CAS:25316-40-9 Purity:>98%

Research Products International Corp Mitomycin C, 5 MG