Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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3,616 – 3,630 of 7,109 results

3,616

Selleck Chemical LLC Ciliobrevin D-5mg

Ciliobrevin D (compound 5) is a cell-permeable, reversible and specific antagonist of AAA+ (ATPases associated with diverse cellular activities) ATPase motor cytoplasmic dynein. Ciliobrevin D perturbs primary cilia formation and blocks Hedgehog (Hh) signaling.

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3,617

Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 100 Milligrams

Nourseothricin Sulfate, also known as Streptothricin, is a natural, broad-spectrum antibiotic derived from Streptomyces species. It is used as a selective agent in molecular biology, genetics, microbiology, and cell culture. It inhibits protein synthesis in bacterial and eukaryotic cells, enabling selection of transformed cells that express the NAT resistance gene. These cells produce Nourseothricin acetyltransferase, which inactivates the antibiotic. Nourseothricin is commonly used in gene expression studies, plasmid maintenance, and to eliminate bacterial or fungal contaminants from cultures, ensuring purity and stability of resistant strains.

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3,618

Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 1 Gram

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3,619

Research Products International Corp Piperacillin, Sodium Salt, 1 Gram

Piperacillin Sodium Salt is a broad-spectrum β-lactam antibiotic. Piperacillin belongs to the class of extended-spectrum penicillins and inhibits bacterial cell wall synthesis. It achieves this by binding to penicillin-binding proteins (PBPs), enzymes involved in the final stages of peptidoglycan synthesis in the bacterial cell wall. This interference results in structural instability and eventual cell lysis.

Piperacillin Sodium Salt may be used for studying antibiotic susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.

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3,620

Medchemexpress LLC Monomethylauristatin F sodium | 1799706-65-2 | 99.6% | 753.94 g·mol⁻¹ | C39H64N5NaO8 | 5 MG

Monomethylauristatin F sodium (MMAF sodium) is the sodium salt of monomethyl auristatin F, a potent tubulin polymerization inhibitor used primarily as a cytotoxic payload in antibody-drug conjugate research and preclinical antitumor studies.

Potent tubulin polymerization inhibitor used in cytotoxic payload research.
High reported purity (99.6%).
Molecular weight 753.94 g·mol⁻¹; formula C39H64N5NaO8.
Available in small research quantities such as 5 mg.
Store at 4°C, protect from light, and store under inert gas where indicated.
Handle as a cytotoxic compound and follow appropriate safety measures and disposal procedures.

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3,621

STEMCELL Technologies Tunicamycin, Size: 5 mg

Tunicamycin is a nucleoside antibiotic and an N-acetylglucosamine phosphotransferase inhibitor (Contessa et al.). It also inhibits protein palmitoylation (Patterson & Skene.). Tunicamycin can be used to induce the unfolded protein response and investigate the mechanism of autophagy (Ding et al.). CANCER RESEARCH· Radiosensitizes human pancreatic cancer cells to chemotherapy (Contessa et al.).· Induces endoplasmic reticulum stress and autophagy in cancer cells (Ding et al.).

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3,622

Medchemexpress LLC Sri-011381 | 1629138-41-5 | 99.4% | 329.48 g/mol | C20H31N3O | 5 MG

SRI-011381 is an orally active small-molecule agonist of the TGF-β/Smad signaling pathway with reported neuroprotective effects in preclinical studies. It is provided for research use in both solid and solution forms and is commonly used to probe TGF-β pathway activation in vitro and in vivo.

Orally active TGF-β/Smad signaling agonist.
Exhibits reported neuroprotective effects in preclinical models.
High reported purity (99.4%).
Molecular weight 329.48 g/mol.
Chemical formula C20H31N3O.
Available as multiple solid sizes and as a 10 mM solution in DMSO.
Suitable for in vitro and in vivo pathway activation studies.

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3,623

Selleck Chemical LLC Rapamycin (Sirolimus) 100mg 53123-88-9 AY 22989NSC-2260804

Rapamycin (Sirolimus, AY 22989, NSC-2260804) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.

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3,624

Medchemexpress LLC JH-RE-06 | 1361227-90-8 | 99.9% | 468.72 | C20H16Cl3N3O4 | 5MG

JH-RE-06 is a small-molecule REV1-REV7 interface inhibitor that disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of POLζ, sensitizing cells to DNA-damaging chemotherapy. It is characterized in cellular and in vivo models for enhancing cisplatin efficacy and reducing therapy-induced mutagenesis; intended for research use only.

Targets REV1-REV7 interface to inhibit TLS.
Sensitizes tumor cells to DNA-damaging agents.
Demonstrated activity in cellular and in vivo models.
High purity suitable for biochemical and cell-based studies.
Soluble in DMSO; available as solid and DMSO solution formats.
Intended for research use only; not for human or clinical use.

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3,625

Medchemexpress LLC 6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid | 96187-53-0 | MFCD00866437 | 99.9% | 375.37 | C23H15F2NO2 | 10 MG

Brequinar is a small-molecule inhibitor of dihydroorotate dehydrogenase (DHODH) used as a research reagent. It shows potent DHODH inhibition (human DHODH IC50 ≈ 5.2 nM) and has reported antiviral activity in preclinical studies. Supplied as a solid for preparing stock solutions, it is intended for laboratory research use only.

Potent DHODH inhibitor with reported human IC50 ≈ 5.2 nM.
High purity as supplied (99.9%).
Molecular formula C23H15F2NO2 and molecular weight 375.37 g/mol.
Supplied as a solid suitable for preparing stock solutions.
Applicable to antiviral and metabolic pathway research.
For research use only; not for human or diagnostic use.

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3,626

Medchemexpress LLC HY-100521 5mg Medchemexpress, GKI-1 CAS: Purity:>98%

Medchemexpress, HY-100521 5mg GKI-1 CAS: GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 µM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 µM, but only weakly affected PKA. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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3,627

Medchemexpress LLC HY-102007A 1mg Medchemexpress, Gamitrinib TPP hexafluorophosphate CAS:1131626-47-5 Purity:>98%

Medchemexpress, HY-102007A 1mg Gamitrinib TPP hexafluorophosphate CAS:1131626-47-5 Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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3,628

Medchemexpress LLC HY-108696 10mg Medchemexpress, GNE-781 CAS:1936422-33-1 Purity:>98%

Medchemexpress, HY-108696 10mg GNE-781 CAS:1936422-33-1 GNE-781 is a highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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3,629

Medchemexpress LLC HY-100619A 5mg Medchemexpress, BMS-986020 (sodium) CAS:1380650-53-2 Purity:>98%

Medchemexpress, HY-100619A 5mg BMS-986020 (sodium) CAS:1380650-53-2 BMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC50s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively. BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF)[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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3,630

Medchemexpress LLC HY-17567B 100mg Medchemexpress, Heparin (Lithium salt) CAS:9045-22-1 Purity:>98%

Medchemexpress, HY-17567B 100mg Heparin (Lithium salt) CAS:9045-22-1 Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Antibiotics

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Selleck Chemical LLC Ciliobrevin D-5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 100 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 1 Gram Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Piperacillin, Sodium Salt, 1 Gram Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Monomethylauristatin F sodium | 1799706-65-2 | 99.6% | 753.94 g·mol⁻¹ | C39H64N5NaO8 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sri-011381 | 1629138-41-5 | 99.4% | 329.48 g/mol | C20H31N3O | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Rapamycin (Sirolimus) 100mg 53123-88-9 AY 22989NSC-2260804 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC JH-RE-06 | 1361227-90-8 | 99.9% | 468.72 | C20H16Cl3N3O4 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid | 96187-53-0 | MFCD00866437 | 99.9% | 375.37 | C23H15F2NO2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-100521 5mg Medchemexpress, GKI-1 CAS: Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-102007A 1mg Medchemexpress, Gamitrinib TPP hexafluorophosphate CAS:1131626-47-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-108696 10mg Medchemexpress, GNE-781 CAS:1936422-33-1 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-100619A 5mg Medchemexpress, BMS-986020 (sodium) CAS:1380650-53-2 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-17567B 100mg Medchemexpress, Heparin (Lithium salt) CAS:9045-22-1 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More