Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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3,751 – 3,765 of 7,082 results

3,751

Enzo Life Sciences Guanfacine. HCl (100mg). CAS: 29520-14-7 / 29110-48-3

Centrally acting α2-adrenergic receptor agonist. In the guinea pig cerebral cortex, the Kd is 20 and 880 nM for the α2A- and the α2C-adrenoceptor, respectively. Antihypertensive agent. Purity: ≥98% (HPLC). Solubility: Soluble in water (25 mg/ml). Long Term Storage: Ambient.

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3,752

Medchemexpress LLC ZT-1a | 212135-62-1 | 99.8% | 445.73 | 100 MG

ZT-1a is a potent, non-ATP-competitive, and selective SPAK inhibitor. It inhibits SPAK activity and decreases SPS1-related proline/alanine-rich kinase (SPAK)-dependent phosphorylation of Na-K-2Cl cotransporter (NKCC1) and K-Cl cotransporters (KCCs).

Potent, non-ATP-competitive, and selective SPAK inhibitor
Inhibits SPAK activity with IC50s of 44.3, 35.0, and 46.7 μM
Inhibits Na-K-2Cl cotransporter (NKCC1)
Stimulates K-Cl cotransporters (KCCs)
Decreases SPAK-dependent phosphorylation
For research use only

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3,753

Medchemexpress LLC Ispinesib | 336113-53-2 | 99.6% | C30H33ClN4O2 | 100 MG

Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), exhibiting a Ki app of 1.7 nM.

Potent and highly specific inhibition of KSP.
Inhibits the growth of BT-474 and MDA-MB-468 cell lines.
Suppresses proliferation and induces apoptosis in prostate cancer cells.
Up-regulates genes for apoptosis and cell cycle arrest, while down-regulating genes for cell proliferation and survival.
Anti-proliferation and pro-apoptotic activities can be enhanced in combination with genistein.
Reduces tumor volume in mouse models bearing various breast cancer xenografts.

Pricing & Availability

3,754

Medchemexpress LLC 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, 4-amino-, 2,2-dioxide, (1R,4S,5S,6S)- | 635318-11-5 | ≥98.0% | C7H9NO6S | 100 MG

LY404039 is a potent, selective, and orally active mGluR2 and mGluR3 agonist. It exhibits >100-fold selectivity for mGluR2/3 over other receptors/transporters and has antipsychotic and anxiolytic effects.

Potent, selective, and orally active mGluR2 and mGluR3 agonist
Ki values of 149 nM and 92 nM for mGluR2 and mGluR3
Exhibits >100-fold selectivity for mGluR2/3 over other receptors/transporters
Has antipsychotic effects
Has anxiolytic effects

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3,755

Medchemexpress LLC Ribostamycin | 25546-65-0 | 99.9% | C17H34N4O10 | 100 MG

Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic effective against both Gram-Negative and Gram-Positive bacterial infections. It also inhibits the chaperone activity of Protein Disulfide Isomerase (PDI). It has been shown to inhibit *Borrelia burgdorferi* and *Escherichia coli* strains in vitro. Studies in rats indicated that ribostamycin causes little nephrotoxicity at a dosage of 40 mg/kg via intramuscular injection daily for 14 days.

Effective against Gram-Negative and Gram-Positive bacterial infections.
Inhibits the chaperone activity of PDI.
Demonstrates *in vitro* activity against *Borrelia burgdorferi*.
Inhibits *Escherichia coli* strains.
Shows low nephrotoxicity in rat studies.

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3,756

AdipoGen Ionomycin (free acid),Chemical. CAS: 56092-81-0.

Ionomycin (free acid), AdipoGen Life Sciences. Chemical. CAS: 56092-81-0. Formula: C41H72O9. MW: 709. Isolated from Streptomyces conglobatus. Antibiotic. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+. Apoptosis inducer. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA. ADAM10 agonist. Potent inducer of shedding CXCL16. TREK-1 channels inhibitor.

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3,757

Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | MFCD13184797 | 99.9% | 306.37 | C17H18N6 | 10 MG

Ruxolitinib (S enantiomer) is the single S enantiomer of ruxolitinib, an orally active and potent Janus kinase (JAK) inhibitor used in preclinical research to probe JAK-dependent signaling and related disease models. It has demonstrated in vitro suppression of interferon-β-induced gene expression and in vivo activity in myeloproliferative neoplasm models.

Orally active, potent JAK inhibitor.
Suitable for in vitro and in vivo preclinical studies.
Chemical formula C17H18N6, molecular weight 306.37.
CAS number 941685-37-6.
Reported purity 99.9%.
Available as solid and solution formats, including 10 mg solid and 10 mM in DMSO.

Pricing & Availability

3,758

Medchemexpress LLC Tildipirosin | 328898-40-4 | MFCD13194925 | 10mg

Tildipirosin | Putity: 99.81% | MW: 734.02 | 328898-40-4 | MFCD13194925 | 10mg

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3,759

Medchemexpress LLC Tunicamycin | 11089-65-9 | 99.9% | 844.94 | C39H64N4O16 | 10 MG

Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT), causing accumulation of unfolded proteins in the endoplasmic reticulum and inducing ER stress. It is used in research to study the unfolded protein response, glycoprotein synthesis, and related cell cycle effects.

Inhibits N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT).
Induces ER stress and activates the unfolded protein response.
Reported antimicrobial and anti-cancer activities in the literature.
Off-white to light yellow solid with high reported purity.
Soluble in DMSO, water (requires pH adjustment), and ethanol; in vivo formulations described.
Powder storage: -20°C (long-term); in solvent: -80°C (months) or -20°C (short-term).

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3,760

Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 99.0% | 10 MG

(3S,4S)-PF-06459988 is the S-enantiomer of PF-06459988, provided as a high-purity research compound that irreversibly inhibits the T790M mutant form of the epidermal growth factor receptor (EGFR). It is intended for biochemical and cellular studies of mutant EGFR signaling, inhibitor selectivity, and related preclinical research applications.

Has selectivity for T790M mutant EGFR.
Acts as an irreversible EGFR inhibitor.
Supplied as a high-purity powder suitable for research use.
Soluble in DMSO at high concentration; in vivo formulations reported.
Stable under recommended frozen storage; follow solvent storage guidelines for prepared solutions.
Suitable for biochemical assays, cellular studies, and selectivity profiling.

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3,761

Sigma Aldrich Fine Chemicals Biosciences Lauric acid natural, >=98%, FCC, FG | 143-07-7 | MFCD00002736 | 5KG

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3,762

Enzo Life Sciences Fluphenazine-N-2-chloroethane . 2HCl (50mg). CAS: 83016-35-7

A potent irreversible inactivator of calmodulin. Possesses potent antiproliferative and cytotoxic activity. It is also an irreversible D2 dopamine receptor antagonist. Alternative name: SKF-7171A. Purity: ≥98%. Solubility: Soluble in DMSO (50mg/ml) or water (10mg/ml warm). Long Term Storage: Ambient.

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3,763

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000299027 AMPICILLIN STANDARD 10MG

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3,764

Medchemexpress LLC Vu0155041 | 1093757-42-6 | 99.10% | C14H15Cl2NO3 | 50 MG

VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD).

Potent and selective positive allosteric modulator (PAM) of mGluR4
EC50s of 798 nM for human mGluR4
EC50s of 693 nM for rat mGluR4
Potential for Parkinson's disease research
Does not affect NMDA receptor currents in striatal medium spiny neurons at 10 μM in vitro
Reverses catalepsy induced by dopamine D2 receptor antagonist Haloperidol in rats
Reverses Reserpine-induced akinesia in rats

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3,765

Medchemexpress LLC FB23 | 2243736-35-6 | 98.9% | 377.22 | 50 MG

FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. It directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

Potent and selective FTO demethylase inhibitor
IC50 of 60 nM against FTO
Directly binds to FTO
Selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity
Inhibits proliferation of acute myeloid leukemia (AML) cells (e.g., NB4 and MONOMAC6)
Suppresses MYC and E2F targets
Activates apoptosis and p53 pathways

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Antibiotics

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Enzo Life Sciences Guanfacine. HCl (100mg). CAS: 29520-14-7 / 29110-48-3 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC ZT-1a | 212135-62-1 | 99.8% | 445.73 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ispinesib | 336113-53-2 | 99.6% | C30H33ClN4O2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, 4-amino-, 2,2-dioxide, (1R,4S,5S,6S)- | 635318-11-5 | ≥98.0% | C7H9NO6S | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ribostamycin | 25546-65-0 | 99.9% | C17H34N4O10 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen Ionomycin (free acid),Chemical. CAS: 56092-81-0. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | MFCD13184797 | 99.9% | 306.37 | C17H18N6 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tildipirosin | 328898-40-4 | MFCD13194925 | 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tunicamycin | 11089-65-9 | 99.9% | 844.94 | C39H64N4O16 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 99.0% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Enzo Life Sciences Fluphenazine-N-2-chloroethane . 2HCl (50mg). CAS: 83016-35-7 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Vu0155041 | 1093757-42-6 | 99.10% | C14H15Cl2NO3 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC FB23 | 2243736-35-6 | 98.9% | 377.22 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More