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Filtered Search Results
Apexbio Technology LLC Clarithromycin 81103-11-9 200mg
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Clarithromycin is a macrolide antibiotic exhibiting inhibitory activity against the cytochrome P450 isoform CYP3A a critical enzyme involved in drug metabolism Through CYP3A inhibition clarithromycin elevates the plasma concentrations of substrates notably statins thereby potentially altering their pharmacokinetic profiles Clarithromycin demonstrates potent CYP3A inhibition with an approximate IC50 value of 32 M making it suitable for in vitro and in vivo research investigating drug-drug interaction mechanisms and pharmacokinetic studies involving CYP3A-dependent pathways Experimental applications include assessing clarithromycin s impact on hepatic CYP3A activity evaluating the metabolic stability of CYP substrates and characterizing interaction risks between concurrent medications that share CYP3A-mediated metabolic routes
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Medchemexpress LLC HY-12912 5mg Medchemexpress, KDU691 CAS:1513879-19-0 Purity:>98%
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Medchemexpress, HY-12912 5mg KDU691 CAS:1513879-19-0 KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16289 5mg Medchemexpress, Lodoxamide (tromethamine) CAS:63610-09-3 Purity:>98%
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Medchemexpress, HY-16289 5mg Lodoxamide (tromethamine) CAS:63610-09-3 Lodoxamide tromethamine (U-42585E) is a medication for the treatment of prophylaxis of mast cell-mediated allergic disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Sibrafiban (RO 48-3657) | 172927-65-0 | 99.7% | 420.47 g/mol | C20H28N4O6 | 5 MG
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Sibrafiban (RO 48-3657) is an orally active, nonpeptide double prodrug of Ro 44-3888 that functions as a selective glycoprotein IIb/IIIa receptor antagonist. It inhibits platelet aggregation and is supplied as a high-purity research chemical for in vitro and preclinical studies.
- Orally active double prodrug with selective glycoprotein IIb/IIIa antagonism.
- Inhibits platelet aggregation for antithrombotic research.
- High purity (≈99.7%).
- Provided as a solid research reagent suitable for in vitro and preclinical assays.
- Recommended powder storage: -20°C for long-term stability.
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Medchemexpress LLC Perifosine | 157716-52-4 | 99.9% | C25H52NO4P | 5 MG
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Perifosine is an oral Akt inhibitor that inhibits the proliferation of various tumor cell lines with IC50s ranging from 0.6 to 8.9 μM. It blocks cell cycle progression of head and neck squamous carcinoma cells at G1-S and G2-M phases by inducing p21WAF1, independent of p53 function. It also inhibits multiple signaling pathways in glial progenitors and can cooperate with temozolomide to arrest cell proliferation in gliomas in vivo. This product is for research use only and not sold to patients.
- Inhibits proliferation of various tumor cell lines
- Blocks cell cycle progression at G1-S and G2-M phases
- Induces p21WAF1, independent of p53 function
- Inhibits multiple signaling pathways in glial progenitors
- Can cooperate with temozolomide to arrest cell proliferation in gliomas in vivo
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Medchemexpress LLC HY-B1790 100mg Medchemexpress, Terconazole CAS:67915-31-5 Purity:>98%
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Medchemexpress, HY-B1790 100mg Terconazole CAS:67915-31-5 Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC L-albizziin | 1483-07-4 | 98.0% | 5 MG
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L-albizziin is a non-proteinogenic amino acid that functions as a sulfhydryl group reagent and a glutamase inhibitor. It is used primarily in vitro for studies of glutamase activity and for cancer research.
- Sulfhydryl group reagent used in biochemical assays.
- Glutamase inhibitor for in vitro research applications.
- High purity: 98.0%.
- White to off-white solid, stable under recommended storage conditions.
- Available in small milligram packages suitable for laboratory studies.
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Medchemexpress LLC HY-N0104 5mg Medchemexpress, Curcumol CAS:4871-97-0 Purity:>98%
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Medchemexpress, HY-N0104 5mg Curcumol CAS:4871-97-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 209219-38-5 | Medchem Express | Nastorazepide | 5mg | 446268750 | HY-17617 | MFCD26142609 | 520.63 | C29H36N4O5
Medchem Express | SU3327 | 5mg | 518570903 | HY-107597 | 40045-50-9 | MFCD01927019 | 261.290 | C5H3N5O2S3
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Medchemexpress LLC HY-19736 5mg Medchemexpress, TY-52156 CAS:934369-14-9 Purity:>98%
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Medchemexpress, HY-19736 5mg TY-52156 CAS:934369-14-9 TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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ILEX LIFE SCIENCES LLC AMPHOTERICINB 250UG/ML 6X100ML
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PAN-Biotech Amphotericin B for cell culture (Fungizone generic), 250 ug/ml (6 x 100 ml). DESCRIPTION: PAN-Biotech Amphotericin B (250 ug/ml) is a generic version of Fungizone that is used in cell culture applications. Amphotericin B is an antifungal agent produced by Streptomyces sp.. Amphotericin B increases fungal plasma membrane permeability by binding to sterols, thereby protecting cell cultures from contamination by yeast and multicellular fungi. APPLICATION: Amphotericin B is often used as an antifungal, anti-yeast and anti-mold agent to prevent fungal contamination of cell cultures. The commonly recommended working concentration ranges from 0.25-2.5 ug/mL (1-10 mL/L). LIQUID/POWDER: Liquid. STERILE: Yes. STORAGE TEMP.: -20°C. MANUFACTURER: PAN-Biotech GmbH. COUNTRY OF ORIGIN: Germany. USAGE: This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures.
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Medchemexpress LLC Clindamycin phosphate | 24729-96-2 | MFCD11982855 | 99.5% | 1 ML
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Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. It is a proagent of Clindamycin that lacks in vitro antimicrobial activity but converts rapidly in vivo to the active parent agent, Clindamycin, through phosphatase ester hydrolysis. It is used in research for conditions like acne and bacterial vaginosis, and it exhibits no cytotoxicity. When combined with platelet-rich fibrin (PRF), PRF-Clindamycin phosphate enhances antimicrobial properties.
- Broad-spectrum bacteriostatic lincosamide antibiotic.
- Proagent of Clindamycin, converting to the active form in vivo.
- Can be used for researching acne and bacterial vaginosis.
- No cytotoxicity observed.
- Enhances antimicrobial properties when combined with platelet-rich fibrin.
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Medchemexpress LLC TTA-A2 | 953778-63-7 | 99.3% | 378.39 | 100 MG
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TTA-A2 is a potent, selective, and orally active T-type voltage-gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. It is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of various human neurological diseases, including sleep disorders and epilepsy.
- Potent, selective, orally active T-type voltage-gated calcium channel antagonist.
- Reduced pregnane X receptor (PXR) activation.
- Equally potent against Cav3.1 and Cav3.2 channels.
- Used in research for neurological diseases, sleep disorders, and epilepsy.
- Exhibits high affinity in α1I binding assay (Ki of 1.2 nM).
- Excellent selectivity over hERG potassium and L-type calcium channels.
- Modifies sleep architecture in rats and mice.
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Medchemexpress LLC HY-111818 5mg Medchemexpress, TH34 CAS:2196203-96-8 Purity:>98%
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Medchemexpress, HY-111818 5mg TH34 CAS:2196203-96-8 TH34, an HDAC6 / 8 / 10 inhibitor with IC 50 s of 4.6 μM, 1.9 μM, and 7.7 μM respectively, shows high selectivity over HDAC1/2/3 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC CCT007093 176957-55-4 10mg
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CCT007093 (CAS 176957-55-4) is a small-molecule inhibitor targeting PPM1D a protein phosphatase involved in cellular stress response pathways It is a thienylidene cyclopentanone derivative that exhibits inhibitory activity against PPM1D with an IC50 of 8 4 M in vitro using recombinant phosphorylated p38 as a substrate In cellular assays CCT007093 selectively reduces viability in MCF-7 cells compared to HeLa cells decreasing cell viability by 40% after two days The compound induces cell death in a p38 kinase-dependent manner and increases p38 phosphorylation an effect reversible by the p38 inhibitor SB203580 CCT007093 is used in research on PPM1D function and in studies of stress signaling and targeted cell death
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