Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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3,781 – 3,795 of 6,971 results

3,781

Cell Signaling Technology Brefeldin A 5 mg

Brefeldin A 5 mg

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3,782

Medchemexpress LLC ESI-09 | 263707-16-0 | 99.15% | 330.77 | 100 MG

ESI-09 is a novel noncyclic nucleotide EPAC antagonist that inhibits EPAC1 and EPAC2 activity, with IC50 values of 3.2 μM for EPAC1 and 1.4 μM for EPAC2. It exhibits increased potency in competing with 8-NBD-cAMP binding and inhibits cAMP-mediated GEF activity. ESI-09 has been shown to inhibit Akt phosphorylation and the migration of pancreatic cancer cells. It also suppresses EPAC1-mediated adhesion of PDA cells on collagen I and reduces bacterial counts in HUVECs infected with *R. australis*, protecting against infection in vivo.

Novel noncyclic nucleotide EPAC antagonist
Inhibits EPAC1 and EPAC2 activity
Increased potency in 8-NBD-cAMP binding competition
Inhibits cAMP-mediated EPAC2 and EPAC1 GEF activity
Inhibits Akt phosphorylation
Suppresses pancreatic cancer cell migration
Reduces bacterial counts post-infection with *R. australis*
Protects against *R. australis* infection in vivo

Pricing & Availability

3,783

Medchemexpress LLC Lyn-1604 dihydrochloride | 2310109-38-5 | 99.6% | 657.54 g/mol | C33H45Cl4N3O2 | 50 MG

LYN-1604 dihydrochloride is a small-molecule activator of UNC-51-like kinase 1 (ULK1) intended for biochemical and cellular research into autophagy and triple-negative breast cancer. The compound activates ULK1 (EC50 = 18.94 nM), shows cellular potency (IC50 = 1.66 μM in MDA-MB-231 cells), and has a measured binding affinity (KD = 291.4 nM). Supplied as the dihydrochloride salt at high purity for assay and dose-response studies.

Potent ULK1 activator (EC50 = 18.94 nM).
Demonstrated cellular activity (IC50 = 1.66 μM in MDA-MB-231 cells).
Measured binding affinity to ULK1 (KD = 291.4 nM).
High purity suitable for biochemical and cellular assays (99.55%).
Available in multiple sizes for dose-range and scale-up studies.

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3,784

Medchemexpress LLC HY-10492 10mg Medchemexpress, Dinaciclib CAS:779353-01-4 Purity:>98%

Medchemexpress, HY-10492 10mg Dinaciclib CAS:779353-01-4 Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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3,785

Medchemexpress LLC Ampicillin trihydrate | 7177-48-2 | 99.9% | 100 G

Ampicillin trihydrate is a broad-spectrum beta-lactam antibiotic effective against various gram-positive and gram-negative bacteria. For research use only.

It inhibits the growth of E. coli of swine origin in a dose-dependent manner, with an effective inhibitory concentration of 2.5 uG/mL.
It is effective in alleviating hemorrhagic enteritis symptoms in pigs.
After oral administration, ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum, and peak concentration in portal blood is twice as high as in peripheral blood.
It also provides neuroprotection against ischemia-reperfusion brain injury by reducing MMPs activities and increasing GLT-1 expression, significantly reducing medial hippocampal cell death following global forebrain ischemia.

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3,786

Bioworld Carbenicillin Disodium Salt, 1 g

Carbenicillin Disodium Salt Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin. Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.Potency >770 μg/mgHygroscopicUSP gradeMay cause sensitization by inhalation and skin contact.For in vitro lab use only. Not for human use or consumption.

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3,787

Medchemexpress LLC Menin-MLL inhibitor 20 | 2448173-47-3 | 98.8% | 100 MG

Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor that exhibits antitumor activities. It is referenced in WO2020142557A1, Intermediate 6.

Irreversible menin-MLL interaction inhibitor
Exhibits antitumor activities
Molecular weight: 612.72
Formula: C33H40N8O4
Appearance: Light yellow to yellow solid
Soluble in DMSO

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3,788

eMolecules 460746-46-7 | Medchem Express | ABT-239 | 5mg | 446260808 | HY-12195 | MFCD13248643 | 330.431 | C22H22N2O

ChemScene | 2-Fluoro-3-nitrobenzaldehyde | 100mg | 559781971 | CS-W003540 | 96516-29-9 | MFCD08669885 | 169.111 | C7H4FNO3

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3,789

Apexbio Technology LLC Ciclopirox ethanolamine,50mg CAS# 41621-49-2

Ciclopirox ethanolamine, a broad-spectrum antifungal agent, inhibits dermatophytes and yeasts pathogenic with a minimal inhibitory concentration (MIC) of 0.98-3.9 μg/mL.Ciclopirox ethanolamine, working as an iron chelator, suppresses a substantial number of clinically relevant dermatophytes, yeasts, and molds, including the frequently azole-resistant Candida species Candida glabrata, Candida krusei, and Candida guilliermondii. Moreover, Ciclopirox has been proved to inhibit a wide range of bacteria in humans, including many gram-positive and gram-negative species pathogenic bacteria. [1] Other sizes are also available. Please inqury us for quote.

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3,790

Medchemexpress LLC HY-107414 5mg Medchemexpress, SKA-121 CAS:1820708-73-3 Purity:>98%

Medchemexpress, HY-107414 5mg SKA-121 CAS:1820708-73-3 SKA-121 is a selective KCa3.1 activator. SKA-121 exhibits EC50s of 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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3,791

Bioworld Carbenicillin Disodium Salt, 25 g

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3,792

Medchemexpress LLC Est73502 monohydrochloride | 2535970-65-9 | 99.6% | C19H27ClF2N2O2 | 10MG

EST73502 monohydrochloride is the hydrochloride salt of EST73502, a research chemical described as a selective, orally active, blood-brain barrier penetrant dual μ-opioid receptor agonist and σ1 receptor antagonist. It is provided for laboratory research use; consult the supplier datasheet and safety data sheet for handling, storage, and certificate of analysis details.

Hydrochloride salt form for improved solubility.
Reported molecular formula C19H27ClF2N2O2.
Molecular weight 388.88 g/mol.
High reported purity in distributor listings; verify with certificate of analysis.
Intended for research use only; not for human or veterinary use.

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3,793

eMolecules 1445251-22-8 | ME0328 | MFCD27991291 | 100mg

Medchem Express | 10-Methoxycamptothecin | 5mg | 532150217 | HY-N0446 | 19685-10-0 | MFCD11975376 | 378.384 | C21H18N2O5

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3,794

Medchemexpress LLC Sulfamerazine-d4 | 1020719-84-9 | MFCD03425631 | 99.0% | 1 MG

Sulfamerazine-d4 is a deuterium-labeled version of Sulfamerazine. Sulfamerazine is a sulfonamide antibacterial that works by inhibiting bacterial synthesis of dihydrofolic acid. It does this by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes.

Can be used as a tracer.
Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.

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3,795

Medchemexpress LLC Kasugamycin hydrochloride hydrate | 200132-83-8 | 99.9% | 1 ML

Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes, exhibiting anti-infective activity. It disrupts tRNA binding by mimicking mRNA nucleotides, which inhibits canonical translation initiation. This compound also increases the sensitivity of mycobacteria to Rifampicin both in vitro and in mouse infection models.

Antibiotic with anti-infective activity
Binds to 30s and 70s ribosomes
Mimics mRNA nucleotides, disrupting tRNA binding
Inhibits canonical translation initiation
Increases sensitivity of mycobacteria to Rifampicin

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Antibiotics

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Cell Signaling Technology Brefeldin A 5 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC ESI-09 | 263707-16-0 | 99.15% | 330.77 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lyn-1604 dihydrochloride | 2310109-38-5 | 99.6% | 657.54 g/mol | C33H45Cl4N3O2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10492 10mg Medchemexpress, Dinaciclib CAS:779353-01-4 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ampicillin trihydrate | 7177-48-2 | 99.9% | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Menin-MLL inhibitor 20 | 2448173-47-3 | 98.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-107414 5mg Medchemexpress, SKA-121 CAS:1820708-73-3 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Est73502 monohydrochloride | 2535970-65-9 | 99.6% | C19H27ClF2N2O2 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfamerazine-d4 | 1020719-84-9 | MFCD03425631 | 99.0% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Kasugamycin hydrochloride hydrate | 200132-83-8 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More