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Filtered Search Results
Selleck Chemical LLC Tigecycline S1403-200mg
Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway
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Selleck Chemical LLC Anisomycin
Anisomycin (Flagecidin Wuningmeisu C) is a bacterial antibiotic isolated from Streptomyces griseolus which inhibits protein synthesis and also act as a JNK activator Anisomycin upregulates autophagy and increases apoptosis
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Medchemexpress LLC HY-15404 5mg Medchemexpress, Darusentan CAS:171714-84-4 Purity:>98%
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Medchemexpress, HY-15404 5mg Darusentan CAS:171714-84-4 Darusentan is a selective endothelin A ( ETA ) receptor antagonist. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a K i =13 nM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Tetracycline HCl 50mg 64-75-5 NCI-c55561
Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Medchemexpress LLC RGB-286638 CDK INHB 5MG
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RGB-286638 CDK Inhibitor 5mg; Cas No.784210-87-3; RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
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Selleck Chemical LLC Alvespimycin (17-DMAG) HCl S1142-5mg
Alvespimycin (17-DMAG NSC 707545 BMS 826476 KOS 1022) HCl is a potent HSP90 inhibitor with IC50 of 62 nM in a cell-free assay
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Medchemexpress LLC MCB-3681 | 790704-42-6 | 99.2% | 626.60 | 50 MG
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MCB-3681 is the antibacterial Oxaquin's active substance, specifically active against gram-positive bacterium. It is intended solely for research purposes and is not for patient use. The compound presents as a solid with a light yellow to yellow appearance.
- Active against gram-positive bacterium
- For research use only
- Solid, light yellow to yellow appearance
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Medchemexpress LLC Lre1 | 1252362-53-0 | 99.8% | 280.78 | C12H13ClN4S | 50 MG
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LRE1 is an allosteric inhibitor of soluble adenylyl cyclase (sAC) used in biochemical and cellular research to modulate cyclic AMP signaling. It binds the bicarbonate activator site of sAC and is supplied as a research-grade reagent with formulation guidance for in vitro and in vivo use.
- Allosteric inhibition of soluble adenylyl cyclase, targeting the bicarbonate activator site.
- High purity (99.8%) suitable for sensitive biochemical and cellular assays.
- High solubility in DMSO for concentrated stock solutions.
- Available as solid and pre-made DMSO solution formats for flexible workflows.
- Documented in vitro and in vivo formulation protocols for experimental use.
- For research use only; not for human or veterinary applications.
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Medchemexpress LLC HY-111746 5mg Medchemexpress, CWHM-1008 CAS: Purity:>98%
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Medchemexpress, HY-111746 5mg CWHM-1008 CAS: CWHM-1008 is a potent and orally active antimalarial agent, with EC 50 values of 46 and 21 nM against drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Spiramycin I | 24916-50-5 | 5 MG
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Spiramycin I is a macrolide antibiotic and antiparasitic that functions by binding to the 50S subunit of the ribosome, thereby blocking peptide chain synthesis. It is intended for research use only and not for sale to patients.
- Exhibits inhibitory activity against Gram-positive bacteria.
- Inhibits B. subtilis, M. luteus, S. aureus, S. epidermidis, and S. pneumoniae.
- Shows cytotoxicity in cancer cells HeLa, KB, MCF-7, HepG2, and U87.
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Medchemexpress LLC Dimetridazole (1,2-dimethyl-5-nitroimidazole) | 551-92-8 | 99.8% | 500 MG
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Dimetridazole is a nitroimidazole antibiotic that inhibits protein synthesis in cultures of *Campylobacter jejuni*. It is genotoxic and can be utilized in the research of protozoal and bacterial infections.
- Inhibits protein synthesis in *Campylobacter jejuni* cultures.
- Shows activity against *Bacteroides fragilis* isolates.
- Induces dose-dependent DNA damage in human lymphocytes.
- Useful in research of protozoal infections.
- Useful in research of bacterial infections.
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Selleck Chemical LLC C-176
STING inhibitor C-176 is a potent small-molecule inhibitor of STING a central signaling component of the intracellular DNA sensing pathway
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Medchemexpress LLC Streptomycin | 57-92-1 | MFCD00072108 | 99.9% | 5 G
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Streptomycin (Agrept) is an effective antibiotic against *M. tuberculosis* and is used for the research of tuberculosis (TB). It is also a bacteriocidal agent for the research of various bacterial infections. Streptomycin binds strongly to nucleic acids, interfering with and blocking protein synthesis while permitting continued RNA and DNA synthesis. As a common antibiotic in culture media, it also acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes.
- Effective antibiotic against *M. tuberculosis* for TB research.
- Bacteriocidal agent for various bacterial infections.
- Binds strongly to nucleic acids, blocking protein synthesis while allowing RNA and DNA synthesis.
- Acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes.
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Medchemexpress LLC HY-14812 5mg Medchemexpress, Karenitecin CAS:203923-89-1 Purity:>98%
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Medchemexpress, HY-14812 5mg Karenitecin CAS:203923-89-1 Karenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13750 5mg Medchemexpress, Ebselen CAS:60940-34-3 Purity:>98%
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Medchemexpress, HY-13750 5mg Ebselen CAS:60940-34-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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