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Filtered Search Results
Apexbio Technology LLC Ceftriaxone Sodium Trihydrate 104376-79-6 50mg
Ceftriaxone Sodium Trihydrate (104376-79-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby disrupting peptidoglycan cross-link formation and compromising bacterial cell wall biosynthesis Ceftriaxone Sodium Trihydrate exerts its biological activity primarily through inhibition of bacterial cell wall synthesis In in vitro studies Ceftriaxone Sodium Trihydrate demonstrates broad-spectrum antimicrobial inhibitory activity with reported IC50 values typically ranging from approximately 0 1 to 4 g/mL depending on the bacterial strain and experimental conditions Based on these pharmacological properties Ceftriaxone Sodium Trihydrate holds research potential in microbiological assays including susceptibility testing drug-resistance research and mechanistic studies involving bacterial PBPs
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Medchemexpress LLC Hydroxypropyl tetrahydropyrantriol | 439685-79-7 | 98.0% | 192.21 g/mol | C8H16O5 | 100 MG
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Pro-xylane (hydroxypropyl tetrahydropyrantriol) is a 30% aqueous cosmetic active and research reagent that supports the skin extracellular matrix. It stimulates biosynthesis pathways in fibroblasts to enhance structural stability of dermal tissue, improves skin hydration and elasticity, and aids collagen and hyaluronic acid production.
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Medchemexpress LLC Protac-o4i2 | 2785323-62-6 | 99.6% | C29H29ClN6O5S | 100 MG
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PROTAC-O4I2 is a PROTAC (proteolysis-targeting chimera) that targets splicing factor 3B1 (SF3B1). It induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells and cellular apoptosis in K562 WT cells. It introduces Thalidomide to ubiquitin E3 ligase cereblon (CRBN) which selectively degrades SF3B1 and inhibits tumor growth in cells.
- Degrades and inhibits SF3B1 in K562 cells.
- Exhibits anti-proliferation effects on SF3B1 WT, SF3B1 OE, and SF3B1 K700E cells.
- Induces FLAG-SF3B1 degradation.
- Increases survival by interfering with tumor maintenance and proliferation in a Drosophila intestinal tumor model.
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Medchemexpress LLC Lyn-1604 dihydrochloride | 2310109-38-5 | 99.6% | 657.54 g·mol-1 | C33H45Cl4N3O2 | 10 MG
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LYN-1604 dihydrochloride is a small-molecule activator of UNC-51-like kinase 1 (ULK1) used to study autophagy and triple-negative breast cancer. Supplied as the dihydrochloride salt, it is provided at high purity for in vitro biochemical and cellular assays.
- Activates ULK1 with nanomolar EC50 (18.94 nM).
- High purity solid suitable for biochemical and cellular research.
- Available as small-mass solids and pre-made DMSO solution for convenience.
- Stable when stored sealed at 4°C; in solvent store at -80°C for long term.
- Dihydrochloride salt form improves solubility for assay preparation.
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Medchemexpress LLC HY-50101A 10mg Medchemexpress, Mavorixafor (trihydrochloride) CAS:2309699-17-8 Purity:>98%
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Medchemexpress, HY-50101A 10mg Mavorixafor (trihydrochloride) CAS:2309699-17-8 Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical ClIndamycIn Phosphate 5g
A lincosamide antibiotic; active against P. acnes in vitro (MIC = 0.02 UG/ml); topical administration reduces the number of bacteria at the burn site in a mouse model of P. acnes burn infection at 1% w/w
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Medchemexpress LLC Jak/HDAC-in-1 | 2284621-75-4 | 450.32 g·mol⁻¹ | C19H21Cl2N7O2 | 10MG
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JAK/HDAC-IN-1 is a small-molecule dual inhibitor of Janus kinase 2 (JAK2) and histone deacetylases (HDAC) with low-nanomolar activity in biochemical assays. It exhibits antiproliferative and proapoptotic effects in several hematological cell lines and is supplied as a research reagent for in vitro studies.
- Potent dual inhibitor of JAK2 and HDAC.
- Low-nanomolar potency in biochemical assays.
- Demonstrates antiproliferative and proapoptotic effects in hematological cell lines.
- Available in small pack sizes suitable for in vitro research.
- Molecular formula C19H21Cl2N7O2; molecular weight 450.32 g·mol⁻¹.
- For research use only; not for human consumption or therapeutic use.
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eMolecules 1037624-75-1 | R428 | MFCD21608463 | 1g
ChemScene | 2-Amino-3-(trifluoromethyl)phenol | 100mg | 536797940 | CS-0079857 | 106877-48-9 | MFCD15526973 | 177.126 | C7H6F3NO
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Medchemexpress LLC HY-112730 10mg Medchemexpress, PEO-IAA CAS:6266-66-6 Purity:>98%
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Medchemexpress, HY-112730 10mg PEO-IAA CAS:6266-66-6 PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Diiodohydroxyquinoline | 83-73-8 | 98.0% | 500 MG
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Diiodohydroxyquinoline (also known as Iodoquinol) is an orally active compound with antiparasitic properties. It has shown potent anti-SARS-CoV-2 activity and mutagenic potential in mice, with ascorbic acid acting as an antimutagen. This compound is promising for research in inflammation, intestinal amebiasis, amebic liver abscess, and chronic nonspecific diarrheas.
- Orally active with antiparasitic properties
- Exhibits mutagenic potential in mice
- Potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells
- Antimutagenic effect can be mitigated by ascorbic acid
- Suitable for research in inflammation
- Suitable for research in intestinal amebiasis
- Suitable for research in amebic liver abscess
- Suitable for research in chronic nonspecific diarrheas
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Medchemexpress LLC HY-111802 100mg Medchemexpress, 3,4'-Dihydroxyflavone CAS:14919-49-4 Purity:>98%
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Medchemexpress, HY-111802 100mg 3,4'-Dihydroxyflavone CAS:14919-49-4 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-101427 5mg Medchemexpress, Bamaquimast CAS:135779-82-7 Purity:>98%
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Medchemexpress, HY-101427 5mg Bamaquimast CAS:135779-82-7 Bamaquimast is an inhibitor of proton pump extracted from patent US2005165041, example 138. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Phosphomycin disodium salt antibacterial MurA inhibitor | MFCD22741288 | 1G
Phosphomycin disodium salt antibacterial MurA inhibitor | Mol Wt: 182.02 | MFCD22741288 | 1G
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Medchemexpress LLC HY-112762A 5mg Medchemexpress, (E)-LHF-535 CAS: Purity:>98%
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Medchemexpress, HY-112762A 5mg (E)-LHF-535 CAS: (E)-LHF-535 is the E-isomer of LHF-535. LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38, has EC 50 s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical Tetrazolyl GlycIn 50mg
An NMDA receptor agonist (IC50 = 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays); It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg); increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury when administered via intrastriatal injection at 5 µM
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