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Filtered Search Results
Medchemexpress LLC 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine | 152121-53-4 | MFCD12405019 | 98.6% | 360.34 g·mol⁻¹ | C20H13FN4O2 | 100 MG
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PD 169316 is a selective, cell-permeable inhibitor of p38 mitogen-activated protein kinase used in biochemical and cellular research. It exhibits an IC50 of approximately 89 nM, is supplied as a high-purity solid powder, and is stored under low-temperature conditions to preserve stability.
- Selective p38 MAPK inhibition (IC50 approximately 89 nM).
- High purity suitable for research applications (reported 98.6%).
- Supplied as a solid powder for ease of handling and formulation.
- Molecular weight 360.34 g·mol⁻¹; formula C20H13FN4O2.
- Stable when stored at recommended low temperatures.
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Medchemexpress LLC HY-111818 5mg Medchemexpress, TH34 CAS:2196203-96-8 Purity:>98%
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Medchemexpress, HY-111818 5mg TH34 CAS:2196203-96-8 TH34, an HDAC6 / 8 / 10 inhibitor with IC 50 s of 4.6 μM, 1.9 μM, and 7.7 μM respectively, shows high selectivity over HDAC1/2/3 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Rifampicin, 5 Grams
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Rifampicin is an antibiotic used for its potent antibacterial properties. It belongs to the class of antibiotics known as rifamycins. Rifampicin is particularly effective against bacteria, including Mycobacterium tuberculosis, which causes tuberculosis, and other bacteria that can lead to various infections.
The mechanism of action of rifampicin involves inhibiting bacterial RNA synthesis by binding to the beta subunit of bacterial DNA-dependent RNA polymerase. This interference disrupts the transcription process, preventing the synthesis of essential RNA and proteins needed for bacterial growth and survival.
Rifampicin is often used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its use contributes to the identification and study of specific bacterial strains.
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Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98%
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HY-10373 5mg Trimetrexate CAS: 52128-35-5 Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Duocarmycin analog | 372954-15-9 | 95.9% | 611.09 g·mol⁻¹ | C34H31ClN4O5 | 1 MG
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Duocarmycin analog is a synthetic analog of duocarmycin used as a DNA alkylator and as an antibody-drug conjugate (ADC) payload for research applications. Supplied as a solid powder, it is intended for laboratory research use only and not for human or clinical use.
- Acts as a DNA alkylator and ADC cytotoxin.
- Available sizes: 1 mg, 5 mg, 10 mg.
- Purity: 95.9%.
- Cas number: 372954-15-9.
- Molecular formula: C34H31ClN4O5; molecular weight: 611.09 g·mol⁻¹.
- Storage: powder -20°C (up to 3 years); in solvent -80°C for 6 months, -20°C for 1 month.
- Appearance: off-white to light yellow solid.
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Medchemexpress LLC MC-Val-Cit-PAB-duocarmycin chloride | 2055896-98-3 | 99.0% | 1055.05 | C54H65Cl2N9O9 | 10 MG
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MC-Val-Cit-PAB-duocarmycin chloride is an antibody-drug conjugate (ADC) agent-linker conjugate that links a valine-citrulline cleavable linker and para-aminobenzyl (PAB) spacer to a duocarmycin payload for use in ADC research. It is supplied as a solid, high-purity compound intended for evaluating linker-payload performance and cytotoxic activity in preclinical studies.
- Cleavable valine-citrulline linker with para-aminobenzyl spacer.
- Duocarmycin payload that binds the DNA minor groove and alkylates DNA.
- High purity (99.0%) solid suitable for research applications.
- Supplied as a 10 MG quantity.
- Store at -80°C, protect from light; unstable in solution.
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Cambridge Isotope Laboratories 5-METHYLTETRAHYDROFOLIC ACID, CALCIUM SALT (GLUTAMIC ACID-13C5, 98%) CHEMICAL PURITY 95%, 5 MG
5-METHYLTETRAHYDROFOLIC ACID, CALCIUM SALT (GLUTAMIC ACID-13C5, 98%) CHEMICAL PURITY 95%, 5 MG
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eMolecules 30562-34-6 | Medchem Express | Geldanamycin | 10mg | 446265202 | HY-15230 | 560.644 | C29H40N2O9
ChemScene | trans-4-(Trifluoromethyl)cyclohexanol | 100mg | 536861023 | CS-W019212 | 75091-93-9 | MFCD12964322 | 168.159 | C7H11F3O
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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Medchemexpress LLC Menin-MLL inhibitor 19 | 2360487-93-8 | 98.1% | 645.70 | 50 MG
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Menin-MLL inhibitor 19 is a potent exo-aza spiro inhibitor of menin-mll interaction, identified as example A17 from patent WO2019120209A1. This compound is intended for research use only and can be utilized in the research of various diseases, including cancer, myelodysplastic syndrome (MDS), and diabetes.
- Potent exo-aza spiro inhibitor
- Used for cancer research
- Used for myelodysplastic syndrome (MDS) research
- Used for diabetes research
- Solid appearance
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Medchemexpress LLC HY-A0166 100mg Medchemexpress, Cilastatin CAS:82009-34-5 Purity:98%
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Medchemexpress,HY-A0166 100mg Cilastatin CAS:82009-34-5 Formula:C16H26N2O5S Cilastatin is a dehydropeptidase inhibitor. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Ionomycin from Streptomyces conglobatus >=98% (HPLC) | 56092-81-0 | MFCD06798385 | 5MG
Ionomycin from Streptomyces conglobatus >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 709 | 56092-81-0 | MFCD06798385 | 5MG
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Medchemexpress LLC HY-13688 100mg , PJ34 (hydrochloride) CAS:344458-15-7 Purity:98%
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Medchemexpress, HY-13688 100mg PJ34 (hydrochloride) CAS:344458-15-7 Formula:C17H18ClN3O2 IC50: 110 nM (PARP1), 86 nM (PARP2) Purity:98% PJ34 hydrochloride is a potent specific inhibitor of PARPl / 2 with IC 50 of 110 nM and 86 nM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Gold Biotechnology Inc Puromycin Dihydrochloride 1 g
Puromycin is an aminonucleoside antibiotic that causes early chain termination within the ribosome during translation. This inhibition of translation is effective in both in vivo and in vitro applications, making it an ideal tool for protein synthesis studies. While selection for E. coli cells is possible with puromycin, it is more commonly and effectively used for mammalian cell selection.
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Medchemexpress LLC HY-100384 10mg Medchemexpress, NKL 22 CAS:537034-15-4 Purity:>98%
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Medchemexpress, HY-100384 10mg NKL 22 CAS:537034-15-4 NKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 μM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13683 500mg , Mifepristone RU486;RU 38486 CAS:84371-65-3 Purity:98%
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Medchemexpress, HY-13683 500mg Mifepristone RU486;RU 38486 CAS:84371-65-3 Formula:C29H35NO2 IC50: 0.2 nM (progesterone receptor, in T47D cells), 2.6 nM (glucocorticoid receptor, in A549 cells) Purity:98% Mifepristone is a progesterone receptor ( PR ) antagonist ( IC 50 =0.2 nM) in a T47D cell-based assay, also is a glucocorticoid receptor ( GR ) antagonist ( IC 50 =2.6 nM) in an A549 cell-based assay. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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