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Filtered Search Results
Medchemexpress LLC Bimatoprost | 155206-00-1 | 99.9% | 5 MG
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Bimatoprost, a prostaglandin analog, is used in the study of open-angle glaucoma, ocular hypertension, and other forms of glaucoma. It reduces intraocular pressure by regulating scleral and trabecular outflow. Topical application can induce fat atrophy and cause a deepening of the eyelid sulcus. This product appears as a white to off-white solid with a purity of 99.94%.
- Reduces intraocular pressure
- Used for open-angle glaucoma and ocular hypertension studies
- Induces fat atrophy
- Purity: 99.94%
- Soluble in Methanol and DMSO
- Molecular weight: 415.57
- Chemical formula: C25H37NO4
- Powder storage: -20°C for 3 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC HY-14989 5mg Medchemexpress, SQ109 CAS:502487-67-4 Purity:>98%
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Medchemexpress, HY-14989 5mg SQ109 CAS:502487-67-4 SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-B0673 1g Medchemexpress, Pirfenidone CAS:53179-13-8 Purity:>98%
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Medchemexpress, HY-B0673 1g Pirfenidone CAS:53179-13-8 Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Eurofins Discoverx AssayComplete Puromycin, 1. (92-0028)
AssayComplete Puromycin is ready-to-use, sterile-filtered puromycin antibiotic shipped as a 10 mg/mL liquid stock. This antibiotic is intended to be used as a selection agent in culture of Eurofins DiscoverX cell-based assays. This product is provided as a 1 mL bottle of liquid at 10 mg/mL. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
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Medchemexpress LLC HY-15142 100mg Medchemexpress, Doxorubicin (hydrochloride) CAS:25316-40-9 Purity:>98%
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Medchemexpress, HY-15142 100mg Doxorubicin (hydrochloride) CAS:25316-40-9 Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy[2]. Doxorubicin hydrochloride inhibits human DNA topoisomerase I with an IC50 of 0.8 μM[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-114277 5mg Medchemexpress, AMG-510 CAS:2296729-00-3 Purity:>98%
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Medchemexpress, HY-114277 5mg AMG-510 CAS:2296729-00-3 AMG-510 is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. AMG-510 irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. AMG-510 is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13441 10mg Medchemexpress, (-)-Blebbistatin CAS:856925-71-8 Purity:>98%
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Medchemexpress, HY-13441 10mg (-)-Blebbistatin CAS:856925-71-8 (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10221 1g Medchemexpress, Vorinostat CAS:149647-78-9 Purity:>98%
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Medchemexpress, HY-10221 1g Vorinostat CAS:149647-78-9 Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis[4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification[7]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10518 10mg Medchemexpress, BMS-345541 (hydrochloride) CAS:547757-23-3 Purity:>98%
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Medchemexpress, HY-10518 10mg BMS-345541 (hydrochloride) CAS:547757-23-3 BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15149 1mg Medchemexpress, Romidepsin CAS:128517-07-7 Purity:>98%
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Medchemexpress, HY-15149 1mg Romidepsin CAS:128517-07-7 Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Cefixime Trihydrate, 1 Gram
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In the life sciences, Cefixime Trihydrate is widely utilized to study bacterial susceptibility and resistance patterns. It helps researchers investigate the effectiveness of antibiotics against various bacterial strains, contributing to a deeper understanding of microbial biology and antibiotic development.
In pharmaceutical research, Cefixime Trihydrate serves as a reference standard for antibiotic formulation and efficacy testing. Researchers rely on it to develop new antibiotics, optimize existing ones, and combat emerging antibiotic-resistant bacteria.
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Research Products International Corp Spectinomycin Sulfate, 1 Gram
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Spectinomycin Sulfate is an antibiotic that belongs to the class of aminocyclitol antibiotics and is effective against a variety of Gram-negative bacteria. It is frequently used as a selective agent in genetic engineering and gene expression studies.
Researchers incorporate Spectinomycin Sulfate into growth media to selectively allow the growth of cells or organisms that have been genetically modified to carry a resistance gene for Spectinomycin. This resistance gene enables the cells to survive and reproduce in the presence of Spectinomycin, while non-transformed cells are inhibited.
Spectinomycin Sulfate is known for its effectiveness against certain antibiotic-resistant strains of bacteria, making it a valuable tool in research. It works by interfering with protein synthesis in bacteria, ultimately leading to cell death.
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Enzo Life Sciences CL-82198 (25mg). CAS: 307002-71-7
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A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation. Purity: ≥98% (TLC). Solubility: Soluble in water (25mg/ml). Long Term Storage: Ambient.
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Enzo Life Sciences Clindamycin. HCl (100mg). CAS: 21462-39-5
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Active against Gram-positive bacteria. Clindamycin binds to the 50S subunit of bacterial ribosomes and suppresses protein synthesis. Alternative name: U-21251F. Purity: ≥95% (HPLC). Solubility: Soluble in water. Long Term Storage: +4°C.
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Enzo Life Sciences Decylubiquinone (10mg). CAS: 55486-00-5
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Inhibits the Ca2+ dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration. Maximum effect on Ca2+ retention capacity of rat liver mitochondria at 100μM. Inhibits etoposide-induced apoptosis in in L929 cells at 5μM. Alternative name: 2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO (10mg/ml). Long Term Storage: -20°C.
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