Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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886 – 900 of 7,041 results

886

Chem-Impex International, Inc. Ciprofloxacin | 85721-33-1 | MFCD00185755 | 1G

Ciprofloxacin, 85721-33-1, MFCD00185755, 1G

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887

Chem-Impex International, Inc. Teicoplanin | 61036-64-4 | MFCD05664625 | 100MG

Teicoplanin, 61036-64-4, MFCD05664625, 100MG

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888

Enzo Life Sciences Alamethicin (5 mg) CAS: 27061-78-5

Antibiotic that increases membrane permeability. Mixture of alamethicin homologs. Membrane permeabilizing antibiotic. Applications include increasing [32P] incorporation into phosphatidylinositol 4-phosphate and permeabilization of sarcoplasmic reticulum vesicles. Causes fusion of lipid vesicles. Alternative Name: U-22324. Formula: C92H150N22O25. MW: 1964.3. CAS: 27061-78-5. Purity: ≥98% (TLC). Sequence Ac-2-MeAla-L-Pro-2-MeAla-L-Ala-2-MeAla-L-Ala-L-Gln-2-MeAla-L-Val-2-MeAla-Gly-L-Leu-2-MeAla-L-Pro-L-Val-2-MeAla-2-MeAla-L-Glu-L-Gln-L-phenylalaninol. Appearance: White to off-white solid. Solubility: Soluble in DMSO, 100% ethanol or methanol. Long Term Storage: +4°C. Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at 0-4°C. Stock solutions are stable for up to 3 months at -20°C.

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889

Sigma Aldrich Fine Chemicals Biosciences Kanamycin sulfate from Streptomyces kanamyceticus | 25389-94-0 | MFCD00070253 | 25 g

Kanamycin sulfate from Streptomyces kanamyceticus | Mol Wt: 582.58 | 25389-94-0 | MFCD00070253 | 25 g

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890

AdipoGen Puromycin . dihydrochloride ,Chemical. CAS: 58-58-2

Puromycin . dihydrochloride , AdipoGen Life Sciences. Chemical. CAS: 58-58-2. Formula: C22H29N7O5 . 2HCl. MW: 471.5 . 72.9. Isolated from Streptomyces alboniger. Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Apoptosis inducer. Inhibits the growth of Gram-positive bacteria, various animal and insect cells. Fungi and Gram-negative bacteria are resistant due to the low permeability to the antibiotic. Antineoplastic agent. Used in cell biology as selective agent in cell culture systems.

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891

Research Products International Corp Mitomycin C, 2 Milligrams

Mitomycin C is a potent antitumor antibiotic. It is derived from Streptomyces caespitosus and exhibits strong cytotoxic properties. It works by cross-linking DNA, inhibiting DNA synthesis, and inducing cell death. Mitomycin C finds applications in molecular biology and cell biology research. It is frequently employed as a DNA cross-linking agent in studies involving DNA damage and repair mechanisms.

Researchers use Mitomycin C to induce DNA adduct formation and study the cellular response to DNA damage. One notable feature of Mitomycin C is its ability to induce DNA cross-links in both dividing and non-dividing cells, making it useful for investigating cellular processes beyond actively dividing cells.

WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

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892

Research Products International Corp G-418 Disulfate 50 mg/ml Solution, 20 Milliliters

G-418 Disulfate, also known as Geneticin, is an aminoglycoside antibiotic derived from Micromonospora rhodorangea. It is widely used in molecular biology and cell culture as a selective agent. G-418 inhibits protein synthesis by targeting the 80S ribosome, blocking translocation. It is commonly used to select genetically modified cells that carry a G-418 resistance gene, typically introduced via plasmid vectors. This allows for the isolation and maintenance of stable transfectants in gene expression, protein production, and cell line development studies. Its selectivity makes it a key tool in genetic engineering.

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893

AdipoGen FK-506,Chemical. CAS: 109581-93-3

FK-506, AdipoGen Life Sciences. Chemical. CAS: 109581-93-3. Formula: C44H69NO12 . H2O. MW: 804.0 . 18.0. Isolated from Streptomyces FCZ0311. Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B; calcineurin), leading to disruption of T cell activation. Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Neuroprotective. Regulates nitric oxide neurotoxicity. Neurotransmitter. Ca2+ release compound. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis inducer.

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894

Research Products International Corp Puromycin Dihydrochloride, 25 Milligrams

Puromycin Dihydrochloride is a potent antibiotic. It is an amino nucleoside antibiotic that mimics the 3'-end of aminoacyl-tRNA. It enters the ribosomal A site during translation, causing premature chain termination and inhibiting protein synthesis. Puromycin is incorporated into growing polypeptide chains, leading to the release of incomplete and nonfunctional peptides.

Widely used as a tool in cell biology to study protein synthesis and investigate translation processes. Its ability to terminate protein synthesis at the ribosome makes it valuable for various applications, including pulse-chase experiments and the analysis of nascent peptides. Puromycin resistance genes are often used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Puromycin, allowing for the selection of transfected or transduced cells.

Pricing & Availability

895

AdipoGen Concanamycin A (high purity),Chemical. CAS: 80890-47-7

Concanamycin A (high purity), AdipoGen Life Sciences. Chemical. CAS: 80890-47-7. Formula: C46H75NO14. MW: 866.1. Isolated from Streptomyces sp. Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1 (Prod. No. BVT-0252). Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production.