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Filtered Search Results
Cayman Chemical Valinomycin Fatty Acids and De
A cyclododecadepsipeptide potassium-selective ionophore antibotic; induces apoptosis in several cell tyes, including CHO cells, by stimulating potassium efflux
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Medchemexpress LLC HY-16592 50mg , Brefeldin A CAS:20350-15-6 Purity:>98%
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HY-16592 50mg Brefeldin A CAS: 20350-15-6 Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator[5]. Brefeldin A inhibits HSV-1 and has anti-cancer activity[5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Carboxyamidotriazole Orotate | 187739-60-2 | 99.7% | 580.76 | 5 MG
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Carboxyamidotriazole Orotate is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. It functions as a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. This product demonstrates anti-tumor, anti-inflammatory, and antiangiogenic effects.
- Functions as a cytostatic inhibitor of nonvoltage-operated calcium channels.
- Inhibits calcium channel-mediated signaling pathways.
- Exhibits anti-tumor effects.
- Exhibits anti-inflammatory effects.
- Exhibits antiangiogenic effects.
- Inhibits cell proliferation of LAMA84R and K562R cell lines.
- Reduces phosphorylation of CrkL.
- Shows dose-dependent inhibition of total and phosphorylated Bcr-Abl levels.
- Displays antitumor activity on CML xenografts.
- Increased survival in animal models.
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eMolecules Medchem Express / BAY 73-6691 / 5mg / 415686514 / HY-104028 / / 794568-92-6 / [null] / 356.730 / C15H12ClF3N4O
Medchem Express / BAY 73-6691 / 5mg / 415686514 / HY-104028 / / 794568-92-6 / [null] / 356.730 / C15H12ClF3N4O
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Lkt Laboratories Imipenem Monohydrate, ≥98%, 25MG
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Carbapenem β-lactam; penicillin binding protein inhibitor. CAS: 74431-23-5. Additional sizes available upon request. Ships from Saint Paul, MN.
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Research Products International Corp 17-AAG [17(Allyamino)-17-demothoxygeldanamycin], 500 Micrograms
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17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognized for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilization.
It is often used as a tool to study Hsp90-dependent processes. By inhibiting Hsp90, 17-AAG impacts the stability and function of various client proteins, many of which are involved in critical cellular processes, including signal transduction and cell cycle regulation.
Researchers use 17-AAG to explore the molecular mechanisms of Hsp90 inhibition, with potential applications in understanding cancer biology and developing therapeutic strategies.
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Medchemexpress LLC (R)-6-chloro-N-(4-fluoro-2-(methylsulfonyl)phenyl)-7-hydroxy-4-oxo-4H-chromene-2-carboxamide | 2438637-65-9 | 99.8% | 435.81 g/mol | C19H11ClFNO6S | 5 MG
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PGAM1-IN-1 is a small-molecule inhibitor of phosphoglycerate mutase 1 (PGAM1) with an enzymatic IC50 of 6.4 μM and demonstrated cellular activity (H1299 proliferation IC50 14.1 ± 1.9 μM). Supplied as a high-purity research reagent, the compound has molecular formula C19H11ClFNO6S and molecular weight 435.81 g/mol. For research use only.
- Inhibits phosphoglycerate mutase 1 with an IC50 of 6.4 μM.
- Shows H1299 cell proliferation inhibition (IC50 14.1 ± 1.9 μM).
- High purity (>99.8%).
- Available as solid and as a 10 mM solution in DMSO.
- Molecular formula C19H11ClFNO6S; molecular weight 435.81 g/mol.
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Medchemexpress LLC Amphotericin B methyl ester | 36148-89-7 | MFCD30719782 | 83.4% | C48H75NO17 | 10MG
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Amphotericin B methyl ester is the methyl ester derivative of amphotericin B, a polyene antibiotic that binds cholesterol and exhibits antifungal activity. It has also been reported to disrupt HIV-1 particle production and inhibit viral replication, making it useful for studies of membrane interactions and viral particle formation. Supplied as a solid with characterized purity and solubility data for research use.
- Methyl ester derivative with documented antifungal activity.
- Cholesterol-binding mechanism, useful for membrane interaction studies.
- Reported to disrupt HIV-1 particle production and inhibit replication.
- Characterized purity for reproducible research results.
- High solubility in DMSO facilitates preparation of in vitro assay solutions.
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Medchemexpress LLC Relebactam | 1174018-99-5 | 348.38 | 5 MG
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Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. It also demonstrates antibacterial activity.
- Diazabicyclooctane inhibitor
- Active against wide spectrum of β-lactamases
- Shows antibacterial activity
- Used in infection research
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Medchemexpress LLC 2,2'-(1,4-phenylene)bis(4,5-diphenyl-1H-imidazole) | 4051-59-6 | 98.0% | 514.62 g/mol | C36H26N4 | 10 MG
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MSX-130 is a small-molecule antagonist of the C-X-C chemokine receptor 4 (CXCR4) used in research to inhibit CXCR4-mediated signaling and reduce cancer metastasis. It is supplied as a solid research reagent with defined storage and solubility recommendations suitable for in vitro and in vivo studies.
- Small-molecule CXCR4 antagonist for research applications.
- High purity (98.0%) suitable for biochemical assays.
- Soluble in DMSO (≈2 mg/mL with warming or sonication).
- Stable as powder when stored at recommended temperatures.
- Available in common research package sizes for dose-response work.
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Cayman Chemical AzIthromycIn-13C-d3 500ug
An internal standard for the quantification of azithromycin by GC- or LC-MS
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eMolecules AstaTech / SR9009 / 0.25g / 411869817 / 40199 / 97.000 / 1379686-30-2 / MFCD29472236 / 437.940 / C20H24ClN3O4S
AstaTech / SR9009 / 0.25g / 411869817 / 40199 / 97.000 / 1379686-30-2 / MFCD29472236 / 437.940 / C20H24ClN3O4S
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Medchemexpress LLC HY-112534 5mg Medchemexpress, GSTO-IN-2 CAS:1202710-57-3 Purity:>98%
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Medchemexpress, HY-112534 5mg GSTO-IN-2 CAS:1202710-57-3 GSTO-IN-2 is a glutathione S-transferase inhibitor with IC50s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112181 10mg Medchemexpress, KO-947 CAS:1695533-89-1 Purity:>98%
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Medchemexpress, HY-112181 10mg KO-947 CAS:1695533-89-1 KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential clinical utility in MAPK pathway dysregulated tumors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112535 5mg Medchemexpress, α-2,3-sialyltransferase-IN-1 CAS:881179-06-2 Purity:>98%
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Medchemexpress, HY-112535 5mg α-2,3-sialyltransferase-IN-1 CAS:881179-06-2 α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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