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Filtered Search Results
Medchemexpress LLC HY-N0849 10mg Medchemexpress, Dictamine CAS:484-29-7 Purity:>98%
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Medchemexpress, HY-N0849 10mg Dictamine CAS:484-29-7 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Mitomycin C, 10 Milligrams
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Mitomycin C is a potent antitumor antibiotic. It is derived from Streptomyces caespitosus and exhibits strong cytotoxic properties. It works by cross-linking DNA, inhibiting DNA synthesis, and inducing cell death. Mitomycin C finds applications in molecular biology and cell biology research. It is frequently employed as a DNA cross-linking agent in studies involving DNA damage and repair mechanisms.
Researchers use Mitomycin C to induce DNA adduct formation and study the cellular response to DNA damage. One notable feature of Mitomycin C is its ability to induce DNA cross-links in both dividing and non-dividing cells, making it useful for investigating cellular processes beyond actively dividing cells.
WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.
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Medchemexpress LLC HY-17576 5mg Medchemexpress, Satraplatin CAS:129580-63-8 Purity:>98%
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Medchemexpress, HY-17576 5mg Satraplatin CAS:129580-63-8 Satraplatin is an alkylating agent, with potent antitumor effect. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences A-804598 >=98% (HPLC) | 1125758-85-1 | 25MG
A-804598 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 315.37 | 1125758-85-1 | 25MG
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Research Products International Corp D-Pantothenic Acid Hemicalcium Salt, 25 Grams
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D-Pantothenic Acid Hemicalcium Salt, 25 Grams
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Medchemexpress LLC Oligomycin | 1404-19-9 | 10 MG
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Oligomycin is an antifungal antibiotic that acts as an inhibitor of H+-ATP-synthase. It blocks oxidative phosphorylation and the electron transport chain. Additionally, Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells. For research use only, it is not sold to patients. The product appears as a solid, white to off-white in color.
- Antifungal antibiotic
- Inhibitor of H+-ATP-synthase
- Blocks oxidative phosphorylation
- Blocks the electron transport chain
- Inhibits HIF-1alpha expression in hypoxic tumor cells
- Suppresses TNF-induced apoptosis by inhibiting the F0 part of H+-ATP-synthase
- Sourced from microorganisms, specifically Streptomyces
- Solid, white to off-white appearance
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eMolecules Medchem Express / Necrostatin 2 / 5mg / 446264392 / HY-14622 / / 852391-19-6 / MFCD19443135 / 277.710 / C13H12ClN3O2
Medchem Express / Necrostatin 2 / 5mg / 446264392 / HY-14622 / / 852391-19-6 / MFCD19443135 / 277.710 / C13H12ClN3O2
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Medchemexpress LLC FB23 | 2243736-35-6 | 98.9% | 377.22 | 50 MG
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FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. It directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
- Potent and selective FTO demethylase inhibitor
- IC50 of 60 nM against FTO
- Directly binds to FTO
- Selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity
- Inhibits proliferation of acute myeloid leukemia (AML) cells (e.g., NB4 and MONOMAC6)
- Suppresses MYC and E2F targets
- Activates apoptosis and p53 pathways
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Medchemexpress LLC ZT-1a | 212135-62-1 | 99.8% | 445.73 | 100 MG
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ZT-1a is a potent, non-ATP-competitive, and selective SPAK inhibitor. It inhibits SPAK activity and decreases SPS1-related proline/alanine-rich kinase (SPAK)-dependent phosphorylation of Na-K-2Cl cotransporter (NKCC1) and K-Cl cotransporters (KCCs).
- Potent, non-ATP-competitive, and selective SPAK inhibitor
- Inhibits SPAK activity with IC50s of 44.3, 35.0, and 46.7 μM
- Inhibits Na-K-2Cl cotransporter (NKCC1)
- Stimulates K-Cl cotransporters (KCCs)
- Decreases SPAK-dependent phosphorylation
- For research use only
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Medchemexpress LLC Streptozotocin | 18883-66-4 | MFCD00006709 | ≥98% | 265.22 | 5 G
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Streptozotocin (STZ) is an antibiotic commonly used in experimental animal models to induce diabetes. It enters B cells via the glucose transporter (GLUT2) and causes DNA alkylation, leading to the apoptosis of β cells. This compound is suitable for constructing models of both type 1 and type 2 diabetes.
- Induces cytotoxicity, oxidative stress, and mitochondrial dysfunction in HepG2 cells.
- Specifically transported by GLUT2 in GLUT2-expressing cells.
- Highly water-soluble and often dissolved in cold acidic citric acid buffer (pH 4.0-4.7).
- Distributes widely throughout the body, including crossing the blood-brain barrier and placenta.
- Undergoes chemical modification in the liver, converting into an active form that causes DNA methylation and damages pancreatic β-cells.
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Medchemexpress LLC HY-B0117C 10mg Medchemexpress, Tigecycline (tetramesylate) CAS: Purity:>98%
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Medchemexpress, HY-B0117C 10mg Tigecycline (tetramesylate) CAS: Tigecycline tetramesylate (GAR-936 tetramesylate) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL [1] . MIC 50 and MIC 90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Gadopentetate Dimeglumine S4852-25mg
Gadopentetate Dimeglumine (Gadopentetic acid dimeglumine Gd-DTPA Meglumine gadopentetate) a complex of gadolinium with a chelating agent diethylenetriamine penta-acetic acid is an extracellular intravenous contrast agent used in magnetic resonance imaging
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Medchemexpress LLC HY-100561 200mg Medchemexpress, Tempol CAS:2226-96-2 Purity:>98%
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Medchemexpress, HY-100561 200mg Tempol CAS:2226-96-2 Tempol is a general superoxide dismutase (SOD)-mimetic drug that efficiently neutralizes reactive oxygen species (ROS). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Potassium clavulanate impurity G European Pharmacopoeia (EP) Reference Standard | 374816-32-7 |
Potassium clavulanate impurity G European Pharmacopoeia (EP) Reference Standard | Mol Wt: 281.26 | 374816-32-7 |
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Research Products International Corp RPI Nalidixic Acid Sodium Salt, 100 Grams
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Nalidixic Acid Sodium Salt is a compound of notable importance in microbiology and pharmaceutical research. This sodium salt formulation of nalidixic acid is a valuable tool for investigating bacterial resistance mechanisms and antibiotic development.
In microbiology, Nalidixic Acid Sodium Salt is widely employed to study bacterial susceptibility and resistance patterns. It serves as a selective agent in microbiological culture media, inhibiting the growth of susceptible bacteria. Researchers use it to assess the effectiveness of antibiotics and to understand the molecular mechanisms behind bacterial resistance, contributing to our understanding of microbial biology and antibiotic resistance.
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