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Filtered Search Results
Medchemexpress LLC HY-100012 5mg Medchemexpress, CBR-5884 CAS:681159-27-3 Purity:>98%
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Medchemexpress, HY-100012 5mg CBR-5884 CAS:681159-27-3 CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC 50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Nafcillin sodium monohydrate | 7177-50-6 | 98.1% | 100 MG
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Nafcillin sodium monohydrate is an antibiotic and a reversible inhibitor of β-lactamase. It is used for the research of staphylococcal infections.
- Targets: bacterial, antibiotic, beta-lactamase.
- Pathway: anti-infection.
- Solid storage: 4°C, sealed, away from moisture.
- Solvent storage: -80°C for 6 months, -20°C for 1 month (sealed, away from moisture).
- In vitro solubility in H₂O: 5.83 mg/mL (12.83 mM), requires ultrasonic.
- In vivo solubility in PBS: 100 mg/mL (220.04 mM), clear solution, requires ultrasonic.
- In vivo solubility in 10% DMSO solutions: ≥ 2.5 mg/mL (5.50 mM), clear solution.
- IC₅₀ target: β-lactam.
- Exhibits bactericidal activity against methicillin-susceptible and methicillin-resistant *Staphylococcus aureus* in mice.
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Sigma Aldrich Fine Chemicals Biosciences Toloxatone >=98% (HPLC), solid | 29218-27-7 | MFCD00865391 | 10MG
Toloxatone >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 207.23 | 29218-27-7 | MFCD00865391 | 10MG
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Sigma Aldrich Fine Chemicals Biosciences Mitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture, 50-07-7, MFCD00078109
Mitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture
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Medchemexpress LLC HY-101419 5mg Medchemexpress, CYM-5541 CAS:945128-26-7 Purity:>98%
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Medchemexpress, HY-101419 5mg CYM-5541 CAS:945128-26-7 CYM-5541 (ML249) is an selective and allosteric S1P 3 receptor agonist with an EC 50 between 72 and 132 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Lamotrigine | 84057-84-1 | 99.97% | 500 MG
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Lamotrigine is a potent, orally active anticonvulsant and antiepileptic agent. It functions by selectively blocking voltage-gated Na+ channels, which stabilizes presynaptic neuronal membranes and inhibits glutamate release. This product is used for research into conditions such as epilepsy and focal seizures.
- Potent and orally active anticonvulsant/antiepileptic agent.
- Selectively blocks voltage-gated Na+ channels.
- Stabilizes presynaptic neuronal membranes.
- Inhibits glutamate release.
- Used for research in epilepsy and focal seizures.
- High purity of 99.97%.
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Medchemexpress LLC MRS-3777 hemioxalate | 1186195-57-2 | 96.3% | 399.40 | 50 MG
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MRS-3777 hemioxalate is a selective adenosine A3 receptor antagonist. It is intended for research use only and is not sold to patients.
- Selective adenosine A3 receptor antagonist.
- Available in various quantities for purchase.
- Documentation available: Data sheet, COA, SDS, handling instructions.
- Solubility information provided for in vitro and in vivo experiments.
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![Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 5 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-K22000-5.0.JPG-250.jpg)
Research Products International Corp Kanamycin Monosulfate [Kanamycin A], 5 Grams
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Kanamycin A is a broad-spectrum aminoglycoside antibiotic derived from Streptomyces kanamyceticus. It is widely used in microbiology, molecular biology, and genetic engineering as a selective agent. Commonly added to culture media, Kanamycin A inhibits the growth of non-resistant bacteria, allowing selection of cells carrying a kanamycin resistance gene. It is frequently used in recombinant DNA experiments and as a selectable marker in plasmids and other vectors. Researchers also use it to study bacterial resistance and antimicrobial efficacy. Its potency and low toxicity make it valuable in protein expression and genetic studies.
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TARGETMOL CHEMICALS INC CLINAFLOXACIN 50MG
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Also available in 5 mg 10 mg 25 mg 100 mg and bulk. Please contact Fisher for quotes. Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic. purity: 97%
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Medchemexpress LLC VU0463271 | 1391737-01-1 | 99.8% | 382.50 | 1 ML
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VU0463271 is a selective KCC2 antagonist, with an IC50 of 61 nM. It offers a potent and selective antagonist activity, making it suitable for various research applications.
- Selective KCC2 antagonist
- IC50 of 61 nM (KCC2)
- Greater than 100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1)
- No activity in a larger panel of GPCRs, ion channels, and transporters
- Rapidly cleared in vitro
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Medchemexpress LLC Acp-5862 | 2230757-47-6 | 98.3% | C26H23N7O3 | 10MG
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ACP-5862 is the major active, circulating, pyrrolidine ring-opened metabolite of acalabrutinib that inhibits Bruton tyrosine kinase (BTK). It has been characterized for its contribution to acalabrutinib's pharmacological activity and displays potent BTK inhibition alongside weak, time-dependent inactivation of select cytochrome P450 enzymes. Supplied for research use with supporting analytical documentation.
- Potent BTK inhibition (IC50 ≈ 5.0 nM).
- Major circulating metabolite of acalabrutinib.
- Weak time-dependent inactivator of CYP3A4 and CYP2C8.
- Available as solid and as a DMSO solution.
- High analytical purity (~98.3% by HPLC).
- Supplied with certificate of analysis and safety data sheet.
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Medchemexpress LLC HY-12353A 10mg Medchemexpress, Pimodivir CAS:1629869-44-8 Purity:>98%
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Medchemexpress, HY-12353A 10mg Pimodivir CAS:1629869-44-8 Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 100 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-N51200-0.1.JPG-250.jpg)
Research Products International Corp Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate], 100 Milligrams
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Nourseothricin Sulfate, also known as Streptothricin, is a natural, broad-spectrum antibiotic derived from Streptomyces species. It is used as a selective agent in molecular biology, genetics, microbiology, and cell culture. It inhibits protein synthesis in bacterial and eukaryotic cells, enabling selection of transformed cells that express the NAT resistance gene. These cells produce Nourseothricin acetyltransferase, which inactivates the antibiotic. Nourseothricin is commonly used in gene expression studies, plasmid maintenance, and to eliminate bacterial or fungal contaminants from cultures, ensuring purity and stability of resistant strains.
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Sigma Aldrich Fine Chemicals Biosciences Clindamycin phosphate for system suitability European Pharmacopoeia (EP) Reference Standard | 24729-96-2 | MFCD07793328 |
Clindamycin phosphate for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 504.96 | 24729-96-2 | MFCD07793328 |
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eMolecules Medchem Express / Pefloxacin-d5 / 1mg / 761041256 / HY-B0147S / / 1228182-51-1 / MFCD16652561 / 338.394 / C17H20FN3O3
Medchem Express / Pefloxacin-d5 / 1mg / 761041256 / HY-B0147S / / 1228182-51-1 / MFCD16652561 / 338.394 / C17H20FN3O3
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