General Cell Lines and Cell Cultures
Biochain Institute Inc Frozen Tissue Array - 37 Different Ovarian Tumors and 3 Corresponding Normal Controls, 5 slides/pk
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's human tumor frozen tissue arrays are designed for studying tumor tissue specific cellular localization of genes or proteins of interest in different human tissues. Same kind of tumors and corresponding normal tissues are mounted on positively charged slides.
Charles River Labs Cell Solutions PB M1 MACROPHAGE CRYO 5M
For Research Use Only. Human Normal Peripheral Blood M1 Macrophages - Cryopreserved, 5 million cells/vial. Derived from purified Monocytes. CD14 monocytes were positively selected via immunomagnetic beads and were cultured in the presence of GM-CSF for 10 days.
MSC SPI Handle, 0.501-0.625 in Range, M3 Size, Aluminum, 1 ea
This pin gage handle is designed to securely hold gage pins for various measurement applications. It accommodates pins within a specific diameter range, providing reliable performance for inspection tasks.
- Accommodates pin diameters from 0.472 in (12.00 mm) to 0.650 in (16.50 mm)
- M3 handle size for precise control
- Constructed from durable aluminum with an anodized coating
- Features an aluminum nut and metal spring-loaded plastic bushing
- No additional bushings required for holding gage pins from 0.501 in to 0.625 in
- Overall length of 6.00 in
Genscript Corporation CHO-K1/GLP1R/G15 Stable Cell
Recombinant CHO-K1 cells stably overexpress human glucagon-like peptide-1 receptor (GLP1R) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/CTLA4 Stable Cell Line
CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4) also known as CD152 (cluster of differentiation 152) is a protein receptor that functions as an immune checkpoint and downregulates immune responses CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation a phenomenon which is particularly notable in cancers It acts as an off switch when bound to CD80 or CD86 on the surface of antigen-presenting cells br/ The CTLA-4 protein is encoded by the Ctla4 gene in mice and the CTLA4 gene in humans
Genscript Corporation CHO-K1/PD-L1 Stable Cell Line
Recombinant CHO-K1 cells stably overexpress human programmed cell death 1 ligand 1 (PD-L1) on the surface The surface expression of PD-L1 is validated by FACS analysis This cell line is recommended for cell-based binding assay to screen antibodies against PD-L1 or to measure binding affinity between PD-L1 and anti-PD-L1 antibodies
Genscript Corporation CHO-K1/SST4/G15 Stable Cell L
Recombinant CHO-K1 cells stably overexpress human somatostatin receptor 4 (SST4) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/TRH1 Stable Cell Line
Thyrtropin-releasing hormone receptor1 (TRH1) is a member of G-protein coupled receptor family A This protein is a receptor for Thyrtropin-releasing hormone (TRH) Human TRH1 is expressed in lymphocytes pituitary gland and CNS It can stimulate the releasing of prolactin (PRL) thyrotropin (TSH) TRH1 receptor knockout mice exhibit a slightly reduced growth rate considerable decrease in serum T sub 3 /sub T sub 4 /sub and prolactin levels but no alteration of thyroid-stimulating hormone levels
Genscript Corporation CHO-K1/mouse CTLA4 Stable Cell
Recombinant CHO-K1 cells stably overexpress Mus musculus cytotoxic T-lymphocyte-associated protein 4 (CTLA4) on the surface The surface expression of mouse CTLA4 is validated by FACS analysis This cell line is designed for cell-based binding for screening antibodies binding with mouse CTLA4 and for evaluating target binding affinity
Genscript Corporation CHO-K1/UT2/G15 Stable Cell Li
The Urotensin II receptor (UT2) also named UTS2R GPR14 which is expressed in endothelium smooth muscle heart and pancreas Pharmacological inhibition of urotensin II receptor interactions prevents renal insufficiency following renal artery ligation
Genscript Corporation CHO-K1/human CD32A 131His Stab
Recombinant CHO-K1 cells stably overexpress human immunoglobulin gamma Fc region receptor II-a (Fc RIIa/CD32A 131His) on the surface The surface expression of CD32A 131His is validated by FACS analysis This stable cell line product is designed for measuring binding affinity and stability of Fc region of antibodies and Fc fusion proteins or antibody based biologics binding with CD32A 131His GenScript also offers CD32A 131Arg stable cell line (Cat No M00887) for Fc RIIa polymorphism study
Genscript Corporation CHO-K1/PD-L2 Stable Cell Line
Programmed cell death 1 ligand 2 (PD-L2) is a protein that in humans is encoded by the PDCD1LG2 gene PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273) Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment The programmed death-1 receptor (PD-1) with its ligands PD-L1 and PD-L2 constitutes an important member of these inhibitory pathways PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs) PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on microenvironmental stimuli
Genscript Corporation B7-H3 4Ig /B7-H3b hFc Chimer
B7-H3 a member of the B7 family of immunomodulatory molecules is overexpressed in a wide range of solid cancers B7-H3 binds to activated T cells via an as yet unidentified receptor In assays using sub-optimal amount so anti-CD3 stimulation 2Ig B7 H3 enhances T cell proliferation T cell interferon-gamma (IFN-gamma) production and cytotoxic T cells induction