Sera
Cayman Chemical DIhomoLInolenIc AcId 100mg
An elongation product of γ-linolenic acid (18:3), rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4); metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins; can reduce atopic dermatitis and atherosclerosis when added to the diet of mice
Cayman Chemical Daclatsvr 50mg
An NS5A inhibitor (Kds = 8 and 210 nM for the NS5A33-202 and NS5A26-202 residues of HCV genotype 1b, respectively); potently inhibits HCV replication in multiple HCV replicon genotypes (EC50s = 9-146 pM) with the highest potency in genotypes 1b and 4a (EC50s = 9 and 12 pM, respectively); disrupts NS5A subcellular localization when used at a concentration of 1 nM; inhibits HCV RNA synthesis and virion assembly and secretion when used at a concentration of 1 nM; inhibits OAT1B1 and OAT1B3 (IC50s = 1.5 and 3.27 µM, respectively)
Cayman Chemical DapoxetInhydrochlorIde 50mg
An analytical reference standard categorized as an SSRI; intended for research and forensic applications
Cayman Chemical AcetylDLcarnItInchlorIde 100mg
A racemic mixture of acetyl-D-carnitine and acetyl-L-carnitine; increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine at 1 mM; decreases the hind limb vasculature blood flow rate in rats; decreases the levels of palmitic acid and oleic acid in the cerebral cortex during the recovery period in a dog model of insulin-induced hypoglycemic brain injury
Cayman Chemical PaeonIflorIn 50mg
A monoterpene glycoside that has analgesic and anti-inflammatory actions in mice
Cayman Chemical SalInomycIn 50mg
An antibacterial and coccidiostat compound that shows selective toxicity for HMLER breast cancer stem cells (IC50 = ~24 μM); 8 μM treatment of 4T1 and MCF-7-Ras breast cancer cell lines decreases cancer stem cell growth ~2-fold and ~3-fold, respectively; 5 mg/kg inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells in mice implanted with SUM159 human breast cancer cells
Cayman Chemical 1H 1H 2H 2HPRfluorodecnsu 50mg
A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
Cayman Chemical ImIpenmhydrate 100mg
An intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 UG/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species
American Research Products Inc Mouse Complement C1q tumor nec
Mouse Complement C1q tumor necrosis factor-related protein 3 (C1QTNF3) ELISA kit from CUSABIO Detection Range 3 12 ng/mL-200 ng/mL Sensitivity 0 78 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical DInIconazole 50mg
A triazole fungicide; inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol; fungicidal against B. cinerea, S. fimicola, F. graminearum, S. cepivorum, and B. sorokiniana (EC50s = 0.012, <0.001, 0.008, 0.02, and 0.06 mg/l, respectively); decreases height and leaf area in bean plants when applied to roots at 5 mg/l; exhibits dose-dependent toxicity in zebrafish
Cayman Chemical Estron 3sulfATsodIum sal 50mg
A steroid; selectively inhibits OATP1B1 over OATP1B3 (IC50s = 0.06 and 19.3 µM, respectively)
Cayman Chemical Importazole 50mg
An inhibitor of importin-β-mediated nuclear import (IC50 = 15 μM in HEK293 cells); does not interfere with transportin-mediated nuclear import or chromosomal maintenance 1 (CRM1)-mediated nuclear export
Cayman Chemical StevIolbIosIde 50mg
A natural non-caloric sweetener and an active metabolite of rebaudioside A; inhibits the proliferation of MDA-MB-231 cells at 250 UG/ml; active against M. tuberculosis (MIC = 3.75 UG/ml)
Cayman Chemical LY2365109hydrochlorIde 50mg
An inhibitor of GlyT1a (IC50 = 15.8 nM in BE2-C cells expressing the human transporter); selective for GlyT1a over GlyT2 (IC50 = >30 µM in RD cells expressing the human transporter); induces locomotor hyperactivity, impaired gait, compulsive walking, and labored breathing, as well as impairs the ability to stand, in rats at 10 mg/kg; prevents maximal electroshock-induced acute seizures in mice at 30 mg/kg and decreases seizure number in an electroshock-induced rat model of chronic epilepsy at 10 mg/kg
Cayman Chemical AbIrateron Acetate 50mg
A CYP17A1 inhibitor (IC50s = 17 and 18 nM for inhibition of C17,20-lyase and 17α-hydroxylase activities, respectively); prodrug form of abiraterone; reduces plasma testosterone levels, increases plasma luteinizing hormone levels, and reduces ventral prostate, seminal vesicle, testis, and kidney weight in mice at 0.1 and 0.5 mmol/kg per day; reduces SARS-CoV-2 viral load in the culture supernatant of infected Vero E6 cells (EC90 = 8.4 μM) and is active in a plaque reduction assay (EC50 = 1.94 μM)