Goat Secondary Antibodies
ABclonal Technology PE anti-Human CD226/DNAM-1
This gene encodes a glycoprotein expressed on the surface of NK cells platelets monocytes and a subset of T cells It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells The protein also plays a role in megakaryocytic cell maturation Alternative splicing results in multiple transcript variants
Cayman Chemical (–)-Menthol, Purity: ≥98%, CAS: 2216-51-5, 5 g
A monoterpene with diverse biological activities; inhibits AChE (Ki = 1.25 mM for the bovine enzyme); decreases expression of the genes encoding topoisomerase I, IIα, and Iiβ in, and cell viability of, SNU-5 gastric cancer cells at 1.6 mM; reduces acetic acid-induced writhing and increases latency to paw licking in a hot plate test in mice from 3-10 mg/kg
ABclonal Technology Human Kappa Light Chain
Immunoglobulins are glycoproteins making up 20% of serum proteins playing a key role in immunity by reacting with antigens They consist of two identical heavy chains and two light chains each with constant and variable regions The constant regions are similar across all immunoglobulins while the variable regions have high sequence variability The heavy chain amino acid sequence defines the immunoglobulin class with five types IgG IgA IgM IgD and IgE IgG has four subclasses and IgA has two In serum IgA and IgG are monomers while IgM is a pentamer and IgA can form polymers The kappa light chain is used for diagnosing leukemias plasmacytomas and some non-Hodgkin s lymphomas It contains one immunoglobulin-like domain
Cayman Chemical Nimustine (hydrochloride), Purity: ≥98%, CAS: 55661-38-6, 250 mg
A pyrimidine analog and nitrosourea alkylating agent; inhibits the growth of U-251MG and EA285 glioma cells at 10 μg/ml; increases the median survival time in a Walker 256 carcinoma rat model of metastatic brain tumors at 30 mg/kg
Cayman Chemical 2-O-α-D-Glucopyranosyl-L-ascorbic Acid, Purity: ≥95%, CAS: 129499-78-1, 25 g
An L-ascorbic acid derivative with antioxidant and radioprotective activities; scavenges DPPH radicals in a cell-free assay (EC50 = 61 μM in 60% ethanol); inhibits γ-radiation-induced cell death in CHO-10B2 and radiosensitive xrs5 cells, as well as UVC- or broadband UVB-induced cell death in CHO-10B2 and UV-sensitive UV135 cells, at 5 mM; increases serum levels of ascorbic acid in rats and guinea pigs at 19.2 and 96 mg/animal, p.o., respectively; reverses weight loss and inhibits subcutaneous hemorrhage in guinea pigs fed a vitamin C-deficient diet at 19.2 mg/animal per day
ABclonal Technology FBP / FOLR1
The protein encoded by this gene is a member of the folate receptor family Members of this gene family bind folic acid and its reduced derivatives and transport 5-methyltetrahydrofolate into cells This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency Due to the presence of two promoters multiple transcription start sites and alternative splicing multiple transcript variants encoding the same protein have been found for this gene
Cayman Chemical 1-Amino-1-deoxy-D-fructose (hydrochloride), Purity: ≥95%, CAS: 39002-30-7, 500 mg
An amino monosaccharide; induces site-specific DNA damage at pyrimidine residues in cell-free assays; 1-amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines
Cayman Chemical β-D-Ribofuranose 1,2,3,5-tetraacetate, Purity: ≥98%, CAS: 13035-61-5, 25 g
A precursor in the synthesis of nucleosides with antiproliferative activity against cancer cells
Cayman Chemical 12-Bromododecanoic Acid, Purity: ≥95%, CAS: 73367-80-3, 1 g
A halogenated form of lauric acid; has been used in the synthesis of clickable forms of myristic acid and as a model fatty acid ligand to determine the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes; reduces virion DNA in the culture supernatant of primary hepatocytes isolated from a duckling model of HBV infection at 10 µg/ml and inhibits HIV replication in CEM-SS T cells (EC50 = 38 µM)
![Cayman Chemical 3,3′-[3-(2-Pyridinyl)-1,2,4-triazine-5,6-diyl]bis[benzenesulfonic acid] (sodium salt), Purity: ≥98% (mixture of isomers), CAS: 1353005-64-7, 10 g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502991760.png-250.jpg)
Cayman Chemical 3,3′-[3-(2-Pyridinyl)-1,2,4-triazine-5,6-diyl]bis[benzenesulfonic acid] (sodium salt), Purity: ≥98% (mixture of isomers), CAS: 1353005-64-7, 10 g
A colorimetric reagent that can be used in the detection of iron; ferrozine-iron complexes can be quantified by colorimetric detection at 562 nm
Kyfora Bio LipoVector Solution 5
Kyfora Bio's LipoVector Solution is a new ready-to-use liposomal transfection reagent designed for the delivery of RNA, DNA, and proteins into eukaryotic cells both in vitro and in vivo. LipoVector can reliably produce recombinant proteins, monoclonal antibodies, and viral vectors in a wide range of cell lines with low cytotoxicity. It supports transient and stable gene expression, co-transfections and is an effective tool for intracellular nucleotide delivery.
Cayman Chemical N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine, Purity: ≥95%, CAS: 68892-41-1, 500 mg
A building block; has been used in the synthesis of oligodeoxyribonucleotides
Cayman Chemical Amfenac (sodium salt hydrate), Purity: ≥98%, CAS: 61618-27-7, 10 g
A COX inhibitor (IC50s = 15.3 and 20.4 nM for the recombinant human COX-1 and COX-2, respectively) and the active metabolite of nepafenac; reduces the migration of 92.1 uveal melanoma cells at 150 nM, as well as proliferation of the same cells when used in combination with ranibizumab
Cayman Chemical Alverine (citrate), Purity: ≥98%, CAS: 5560-59-8, 5 g
An antispasmodic agent; suppresses contractions induced by potassium or ACh in isolated guinea pig detrusor smooth muscle; blocks spontaneous and vagal-stimulated colonic motility in rabbits; reduces the number of abdominal contractions induced by 5-HTP or high volume rectal distension in rats at 75 μg/animal
Cayman Chemical Sclareol, Purity: ≥98%, CAS: 515-03-7, 10 g
A diterpene with diverse biological activities; active against A. naeslundii, P. gingivalis, and P. anaerobius bacteria (MICs = 12.5, 6.2, and 3.1 μg/ml, respectively); inhibits LPS-induces increases in NO production and COX-2 and iNOS protein levels in RAW 264.7 macrophages at 5 and 10 μg/ml; reduces λ-carrageenan-induced hind paw edema in mice at 10 mg/kg; inhibits the growth of HCT116 cells (GI50 = 34 μM); induces apoptosis and halts the cell cycle at the G1 phase in HCT116 cells at 100 μM; reduces tumor growth in an HCT116 mouse xenograft model at 275 mg/kg, i.p., encapsulated in liposomes