Goat Secondary Antibodies
Cayman Chemical Pentadecanoyl-L-carnitine (chloride), Purity: ≥98%, CAS: 173686-57-2, 50 mg
A CB receptor agonist (EC50s = 3.7 and 3.2 µM for CB1 and CB2 receptors, respectively, in a cAMP modulation assay); a 5-HT1A and 5-HT1B agonist (EC50s = 9.6 and 9.3 µM, respectively); a histamine H1 and H2 antagonist (EC50s = 10.9 and 6.1 µM, respectively); inhibits T cell proliferation in an SAg primary human cell system; reduces CCL2 levels in an Mphg primary human cell system
Cayman Chemical 4-(2-Acetoxyacetyl)phenyl acetate, Purity: ≥95%, CAS: 42528-99-4, 100 mg
A synthetic intermediate; has been used in the synthesis of phenethylamine metabolites
Cayman Chemical 2C-iP (hydrochloride), Purity: ≥98%, CAS: 1498978-47-4, 50 mg
A phenethylamine whose physiological and toxicological properties have not been investigated; intended for research and forensic applications
Cayman Chemical PPAR2regIonAB MoncLNal100uL
An internal standard for the quantification of hydroflumethiazide by GC- or LC-MS
Cayman Chemical Furazolidone, Purity: ≥98%, CAS: 67-45-8, 50 g
A nitrofuran antiprotozoal and antibacterial agent; active against G. lamblia trophozoites (IC50 = 2.9 µM), as well as metronidazole-susceptible and -resistant T. vaginalis clinical isolates (MLCs = Salmonella, Shigella, E. coli, and V. parahaemolyticus (MICs = ≤0.5-4 µg/ml); reduces splenic and hepatic parasite burden in a golden hamster model of L. chagasi infection
Cayman Chemical 5-(4,6-Dichloro-s-triazin-2-ylamino)fluorescein (hydrochloride), Purity: ≥98%, CAS: 21811-74-5, 250 mg
An amine-reactive fluorescent protein-labeling agent; has been conjugated to IgG for use as fluorescent antibodies and as a pre-column or on-column reagent to label amino acids and amino acid-containing compounds; has been used as a derivatizing agent in the analysis of ephedrine and pseudoephedrine; ex/em = 492/513 nm, respectively
Cayman Chemical Syringaldehyde, Purity: ≥98%, CAS: 134-96-3, 10 g
A polyphenol; inhibits LPS-induced COX-2 activity in RAW 264.7 cells (IC50 = 19.23 µM); inhibits proliferation of HCT116, Caco-2, and HT-29 colon cancer cells (IC50s = 56.3, 35.9, and 68.6 µM, respectively); decreases plasma glucose levels in a rat model of STZ-induced diabetes ranging from 1.8 to 7.2 mg/kg; reduces infarct size in a rat model of isoproterenol-induced myocardial infarction at 25 and 50 mg/kg
Cayman Chemical Succinylcholine (chloride hydrate), Purity: ≥95%, CAS: 6101-15-1, 25 g
An agonist of muscle-type nAChRs (EC50 = 10.8 µM in X. laevis oocytes expressing the human receptor); selective for the muscle-type nAChR over α3β2, α3β4, α4β2, or α7 subunit-containing neuronal nAChRs (IC50s = >100 µM); induces neuromuscular block in phrenic nerve-stimulated isolated rat phrenic nerve-diaphragm preparations at 600 µg
Cayman Chemical Zebrafish Peroxisome Proliferator-Activated Receptor Gamma Reporter Assay System, 96 Well
zPPARγ Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments. [INDIGO Catalog Nos. Z00101-32, Z00101]
Cayman Chemical HeTRochromatInProteIn1H100uL
An Mps1/TTK inhibitor (IC50 0.182 UM) selective for Mps1/TTK over a panel of 59 additional kinases (IC50s 5 UM for all) accelerates mitosis reducing the length of mitosis by approximately 3-fold in U2OS cells induces aneuploidy and apoptosis in A2780 ovarian cancer cells at 1 UM as well as inhibits proliferation in a panel of 127 cancer cell lines (IC50s 0.192-10 UM) reduces tumor growth in an A2780 mouse xenograft model at 90 mg/kg per day
Cayman Chemical L-Norvaline, Purity: ≥95%, CAS: 6600-40-4, 100 g
An inhibitor of arginase and p70S6K1; inhibits arginase-mediated urea production in J774A.1 macrophage lysates at 10 mM; inhibits TNF-α-induced p70S6K1 activation in HUVECs at 20 mM; reduces microgliosis and the level of amyloid-β fibrils in the hippocampus, as well as improves learning and memory in the Morris water maze in the 3xTg mouse model of Alzheimer’s disease
Cayman Chemical N-(3-Phenylpropionyl)glycine, Purity: ≥98%, CAS: 56613-60-6, 500 mg
An acylglycine; urinary levels are increased in patients with MCAD deficiency
Cayman Chemical β-Naphthoflavone, Purity: ≥98%, CAS: 6051-87-2, 5 g
An AhR agonist; activates transcription of CYP1A1 at 1 and 10 µM in HepG2 cells; inhibits hydrogen peroxide-induced apoptosis, as well as increases the activity of CAT and SOD and decreases the activity of MDA, in SH-SY5Y cells at 10 µM; has been used as a positive control for the induction of AhR transcriptional activity
Cayman Chemical Levomefolate (calcium salt hydrate), Purity: ≥98%, 1 g
A biologically active form of folic acid; methyl-group donor involved in the conversion of homocysteine to methionine; important for prevention of neural tube defects
Cayman Chemical Thiabendazole, Purity: ≥98%, CAS: 148-79-8, 50 g
A broad-spectrum anthelmintic active against a variety of helminths; kills greater than 95% of adult worms from ten genera; inhibits egg production and disrupts larval development; inhibits fumarate reductase in helminths, blocking energy production through the citric acid cycle; inhibits methionine aminopeptidase in E. coli (Ki = 40 nM; IC50 = 47.2 nM)