Goat Secondary Antibodies
Cayman Chemical AmIodaronhydrochlorIde 10g
A class III antiarrhythmic agent; inhibits KCNH2 with an IC50 value of 1 µM; also inhibits CYP2C8 and CYP3A4 in vitro at low micromolar concentrations
Revvity Health Sciences Inc HTRF Human IL-6 / IL6R Binding Kit, 500 Assay Points
HTRF Human IL-6 / IL6R Binding Kit, 500 Assay Points
Cayman Chemical Vonpraznfumarate 5g
A selective and reversible proton pump inhibitor; inhibits gastric H+/K+ ATPase (IC50 = 17 nM); does not inhibit porcine Na+/K+ ATPase activity (10 µM); maintains its inhibitory effect in weakly acidic and neutral pH conditions (IC50s = 19 and 28 nM, respectively); inhibits histamine-stimulated acid secretion in a dose-dependent manner in rats (1, 2, and 4 mg/kg); inhibits acid secretion for more than 48 hours in dogs (0.1 to 1 mg/kg)
ABclonal Technology NMNAT2 Rabbit pAb
This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed, this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology HSP47/SERPINH1 Rabbit pAb
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Cayman Chemical Eicosapentaenoyl Ethanolamide
An internal standard for the quantification of EPEA by GC- or LC-MS
ABclonal Technology ECI2 Rabbit pAb
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
Cayman Chemical Docetaxelhydrate 250mg
A microtubule-stabilizing agent; promotes microtubule assembly in a cell-free assay at 20 µM; is cytotoxic to J774.2 cells (EC50 = 0.05 µM); inhibits tumor growth in several cancer models, including B16 murine melanoma and P388 murine leukemia models
Cayman Chemical DexmedetomIdIn 250mg
An α2-AR agonist; selectively binds to α2-ARs over α1-ARs (Kis = 0.015 and 5 nM, respectively); prevents increases in CTnI, as well as reduces myocardial apoptosis, pyroptosis, and ferroptosis in a mouse model of CLP-induced sepsis at 50 UG/kg; induces sedation and decreases mechanical nociception in cats at 40 UG/kg
Cayman Chemical 1 2 3TrIheptnoyl GlycRol 500mg
A triacylglycerol; increases levels of propionyl-, pentanoyl-, and heptanoyl carnitine in mouse blood when administered as 35% of calories in the diet; delays the development of corneal kindling-induced seizures in mice and increases the PTZ tonic extension threshold during the chronically epileptic stage in a mouse model of pilocarpine-induced status epilepticus at 35% of calories in the diet
Cayman Chemical RoxatIdIn Acetatehydrochlo 1g
A competitive histamine H2 receptor antagonist upon conversion to its active metabolite reduces both intracellular cAMP concentrations and gastric acid secretion by parietal cells
