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Bioassays, kits, and reagents used to analyze various properties of living cell samples. Products include apoptosis assays, signal transduction assays, and cell growth and differentiation assays.
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UK122 TFA is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. It exhibits minimal or no inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). This 4-oxazolidinone analogue acts as an anticancer agent that hinders cancer cell migration and invasion. This product is intended for research use only.
Potent and selective uPA inhibitor
Inhibits cancer cell migration and invasion
Minimal inhibition of tPA, plasmin, thrombin, and trypsin
Suitable for in vitro studies
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ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with an IC₅₀ value of 1.22 μM. It demonstrates anti-tumor activity by inhibiting the growth of cervical cancer and glioblastoma cells.
Inhibits growth of cervical cancer and glioblastoma cells
IC₅₀ value of 1.22 μM for ROS kinase
Tested on HeLa, U138, U87, LN18, and U118 cells
Effective at concentrations from 1 to 100 μM
EC₅₀ values for HeLa, U138, U87, LN18, and U118 cells were 20, 8, 8, 12, and 7 μM, respectively.
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Hydroxyproline Assay Reagent 1 has been tested and formulated to work exclusively with Cayman’s Total Collagen/Hydroxyproline Assay Kit (Item No. 702440).
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A fluorescent DNA probe; forms a fluorescent complex by binding to the minor groove of adenine and thymine-rich sequences; displays an emission maximum of 465 when bound to dsDNA upon excitation at 350 nm; has been used as a marker of nuclei in cell cycle studies and to distinguish nuclear morphology in apoptotic cells
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Potent, selective, orally bioavailable spleen tyrosine kinase (SYK) inhibitor with sub-nanomolar potency (IC50 = 0.31 nM). Characterized for in vivo oral exposure and intended for research into autoimmune disorders and hematologic cancers. Supplied as a high-purity white to off-white solid with documented solubility and storage recommendations.
Sub-nanomolar inhibitory potency against SYK (IC50 = 0.31 nM).
Orally bioavailable with demonstrated oral exposure in rodent models.
High purity suitable for biochemical and cellular assays.
Well-characterized solubility protocols for in vivo formulation.
Stable under recommended storage conditions.
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The R-PLEX Rat IL-13 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures rat interleukin 13 (IL-13) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay has high specificity and shows minimal cross-reactivity The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker reagents and calibrator The assay takes 3 5 hours to complete and has a sensitivity of 0 3 pg/mL
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The Meso Scale Discovery R-PLEX Rat IL-4 Assay is a multiplex immunoassay panel that allows simultaneous measurement of rat interleukin 4 (IL-4) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements The assay requires 50 L of sample and can be read on MSD instrument platforms The R-PLEX Rat IL-4 Assay provides a reproducible and sensitive method for measuring rat IL-4 levels in research studies
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The Meso Scale Discovery Rat NT-proANP Kit is an electrochemiluminescent immunoassay for the quantitative determination of NT-proANP in rat serum plasma and cell culture supernatants The assay uses MSD s proprietary SULFO-TAG labels and MULTI-ARRAY technology with triplexed immunoassays to provide sensitive accurate and rapid quantification of NT-proANP from a small sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG calibrators and sample diluent The kit has a typical sensitivity of 0 3 pg/mL and an assay time of 2 5 hours
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