Signal Transduction Reagents and Kits
Promega VRK2 Kinase Enzyme System, 10microg
Recombinant human VRK2 (1-375) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. VRK2 (also known as vaccinia related kinase 2) is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.
Promega InsR Kinase Enzyme System, 1mg
Recombinant human InsR (amino acids 1011-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. InsR is the insulin receptor tyrosine kinase that is involved in insulin signaling.
Promega EIF2AK2 Kinase Enzyme System, 10microg
Recombinant human EIF2AK2 (252-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EIF2AK2 (also known as double-stranded RNA-activated protein kinase) is shown to be involved in HIV/gp120-associated neurodegeneration.
Promega MRCK alpha Kinase Enzyme System, 10microg
Recombinant human MRCKalpha (1-473) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega PRKG1 (PKG) Kinase Enzyme System, 10microg
Recombinant full-length human PRKG1 (PKG) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PRKG1 is a homodimer, with each monomer containing a regulatory cGMP-binding domain and a catalytic domain.
Promega RIPK2 Kinase Enzyme System, 10microg
RIPK2 (RIP2; RICK) is a death domain-containing protein kinase encoding a predicted 540-amino acid protein that contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain.
Promega ADP-Glo™ Kinase Assay + PASK Kinase Enzyme System
Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.
Promega EGFR (T790M, L858R) Kinase Enzyme System, 1mg
Recombinant human EGFR (T790M, L858R) (amino acids 695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EGFR is receptor for members of the EGF family and a transmembrane glycoprotein that has tyrosine kinase activity.
Promega RET (Y791F) Kinase Enzyme System, 1mg
Recombinant human RET (Y791F) (amino acids 658-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega DYRK2 Kinase Enzyme System, 1mg
Recombinant full-length human DYRK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega FGFR2 Kinase Enzyme System, 1mg
Recombinant human FGFR2 (285-end) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. FGFR2 is a member of the fibroblast growth factor receptor family, which play a role in mitogenesis and differentiation.
Promega ACK Kinase Enzyme System, 1mg
ACK is a tyrosine kinase that binds CDC42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42Hs.
Promega PAK1/CDC42 Kinase Enzyme System, 10microg
Recombinant full-length human PAK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag and combined with CDC42 at a ratio of 1:4 (PAK1:CDC42) in vitro. PAK1 is a member of the p21-activated kinases (PAKs).
Promega CLK3 Kinase Enzyme System, 10microg
Recombinant full-length human CLK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CLK3, also known as CDC-like kinase 3, encodes a serine/threonine-type protein kinase with a non-conserved N-terminal domain.
Promega ADP-Glo Kinase Assay with PIP2:3PS, 1,000 assays
The ADP-Glo Kinase assay and lipid kinase substrates PIP2:3PS and PI:3PS are components of the PI3K-Glo Class I Kinase Profiling System that are available for purchase separately.