General Clinical Chemistry Analyzers and Accessories
AdipoGen N1-Acetylsulfamethoxazol
Chemical. CAS 18607-98-2. Formula C12H13N3O4S. MW 295.31. Synthetic Antibacterial pro-drug of sulfamethoxazole.
AdipoGen N4-Acetylsulfamethoxazole
Chemical. CAS 21312-10-7. Formula C12H13N3O4S. MW 295.3. Synthetic. This is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation, catalyzed by liver extramitochondrial N-acetyl transferases. Acetyl-Sulfamethoxazole is excreted in urine. Both compounds can be used as a probe for the molecular percentage enrichement of liver extramitochondrial acetyl-CoA. Acetyl-Sulfamethoxazole can also be used as a reference for sulfamethoxazole impurity and waste determination.
AdipoGen Ajmalicine
Chemical. CAS 483-04-5. Formula C21H24N2O3. MW 352.43. Synthetic. Alkaloid used to study its effects as an antagonist of adrenergic and nicotinic receptors.
AdipoGen Amicarbazone
Chemical. CAS 129909-90-6. Formula C10H19N5O2. MW 241.3. Synthetic. Herbicide with a broad spectrum of weed control. Potent inhibitor of photosynthetic electron transport, inducing chlorophyll fluorescence and interrupting oxygen evolution via binding to the Qb domain of photosystem II PSII. Compound can be used as analytical reference material.
AdipoGen Azimsulfuron
Chemical. CAS 120162-55-2. Formula C13H16N10O5S. MW 424.4. Synthetic. Reference standard.
AdipoGen 3 5-Dimethyl-NAPQI
Chemical. CAS 74827-85-3. Formula C10H11NO2. MW 177.2. Synthetic Metabolite. Oxidizing analog of N-acetyl-p-benzoquinone imine NAPQI, a toxic metabolite of acetaminophen paracetamol. Primarily oxidizes protein thiols. Shows cytotoxic properties, through disruption of intracellular Ca2 homeostasis. Compound can be used as analytical reference material.
AdipoGen BEP
Chemical. CAS 878-23-9. Formula C7H9BBrF4N. MW 273.86. Synthetic Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or Calpha,Calpha-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.
AdipoGen N1-Acetylsulfamethoxazol
Chemical. CAS 18607-98-2. Formula C12H13N3O4S. MW 295.31. Synthetic Antibacterial pro-drug of sulfamethoxazole.
AdipoGen N4-Acetylsulfamethoxazole
Chemical. CAS 21312-10-7. Formula C12H13N3O4S. MW 295.3. Synthetic. This is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation, catalyzed by liver extramitochondrial N-acetyl transferases. Acetyl-Sulfamethoxazole is excreted in urine. Both compounds can be used as a probe for the molecular percentage enrichement of liver extramitochondrial acetyl-CoA. Acetyl-Sulfamethoxazole can also be used as a reference for sulfamethoxazole impurity and waste determination.
AdipoGen R-BAIBA
Chemical. CAS 2140-95-6. Formula C4H9NO2. MW 103.12. Synthetic Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase DPD, in what constitutes the first step of the pyrimidine degradation pathway.
AdipoGen S-BAIBA
Chemical. CAS 4249-19-8. Formula C4H9NO2. MW 103.12. Synthetic Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase DPD, in what constitutes the first step of the pyrimidine degradation pathway.
AdipoGen R-BAIBA
Chemical. CAS 2140-95-6. Formula C4H9NO2. MW 103.12. Synthetic Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase DPD, in what constitutes the first step of the pyrimidine degradation pathway.
YSI 3P LifeScience SUCROSE MEMBRANE 4/PK
Sucrose Membranes. Used to measure sucrose on YSI 2700, 2900 Series and 7100 analyzers.
AdipoGen Chloroquine diphosphate
Chemical. CAS 50-63-5. Formula C18H26ClN3 . 2H3PO4. MW 319.9 . 196.0. Chloroquine is a commonly used antimalarial drug, more toxic than its derivative hydroxychloroquine Prod. No. AG-CR1-3720. Chloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their strong antiproliferative, antimutagenic, epigenetic and autophagy inhibiting and apoptosis inducing activities. Chloroquine is used to treat rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid antibody syndrome and Sjögrens syndrome. Chloroquine interfers with lysosomal activity and autophagy, interacts with membrane stability and alters signaling pathways and transcriptional activity, which can result in inhibition of cytokine production and modulation of certain co-stimulatory molecules.
AdipoGen Ruxolitinib free base
Chemical. CAS 941678-49-5. Formula C17H18N6. MW 306.4. Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 IC50=322nM. Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro.