Custom Enzymes and Inhibitors
Abnova™ Leukocyte Aggregation Inhibitor
Leukocyte Aggregation Inhibitor suppresses leukocyte aggregation
Sigma Aldrich Fine Chemicals Biosciences Protector RNase Inhibitor | 2000 units
Protector RNase Inhibitor (40 U/μl) in storage buffer: 20 mM HEPES-KOH, 50 mM KCl, 8 mM dithiothreitol, 50% glycerol (v/v), pH approximately 7.6 (+4°C).
Reprocell CHIR99021 IN SOL 2MG-10MM
The aminopyrimidine CHIR99021 is the most selective inhibitor of glycogen synthase kinase 3i� (GSK-3i�) reported to date1,2. Unlike other potent inhibitors of GSK-3, CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3i� compared to CDKs3. along with the elimination of differentiation-inducing signaling from mitogen-activated protein kinases, using CHIR99021 to block the activity of GSK-3i� enables the self-renewal of embryonic stem cells4. Stemoleculea, c CHIR99021 in Solution is a ready to use 10 mM stock solution for stem cell culture.
Reprocell Y27632 2MG IN SOLUTION
Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor1. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency2. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors3. Y27632 in combination with Pifithrin-a� significantly improves cell recovery after cryopreservation4.
Selleck Chemical LLC Y-27632 2HCl 2mg 129830-38-2
Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Reprocell STEMOLECULE CHIR99021 (10MG)
Size 2 mg (Cat. No. 04-0004) 10 mg (Cat. No. 04-0004-10) Alternate Name 6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2 pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile Chemical Formula C22H18Cl2N8 Molecular Weight 465.34 CAS Number 252917-06-9 Purity Greater than 95% by HPLC analysis Formulation Off-white solid Solubility Reconstitute in DMSO to the desired concentration. For reconstitution instructions please reference product specifications sheet. Storage and Stability Store powder at 4°C protected from light. Following reconstitution, store aliquots at -20°C. Stock solutions are stable for 6 months when stored as directed. Quality Control The purity of CHIR99021 was determined by HPLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of CHIR99021 was tested on mouse embryonic stem cells.
Sigma Aldrich Fine Chemicals Biosciences Protease from Streptomyces griseus Type XIV, >=3.5 units/mg solid, powder | 9036-06-0 | MFCD00132092 | 100MG
Protease from Streptomyces griseus Type XIV, >=3.5 units/mg solid, powder | 9036-06-0 | MFCD00132092 | 100MG
Selleck Chemical LLC BORTEZOMIB 10MM (1ML IN DMSO)
Bortezomib 10mM (1mL in DMSO) | 179324-69-7 | 1ml *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Reprocell STEMOLECULE WNT INHB IWP-2 2MG
Stemolecule™ Wnt Inhibitor IWP-2. Stemolecule Wnt Inhibitor IWP-2 was identified in a high throughput screen for antagonists of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity. It also blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin1.
Cederlane FSG67 Inhibitor of Glycerol 3-Phosphate Acyltransferase. 10mg
Inhibitor of Glycerol 3-Phosphate Acyltransferase. 10mg. CAS: 1158383-34-6; 98% by TLC NMR (Conforms) Focus Biomolecules Catalog# 10-4577.
Sigma Aldrich Fine Chemicals Biosciences Protamine sulfate, MFCD00132091, 10g
Meets USP testing specifications, Synonym: Protamine sulfate, Salmine sulfate from salmon sperm; Protamine sulfate is a cationic polypeptide having a molecular weight of 5 kDa, isolated from salmon sperm.
Reprocell Stemolecule XAV939, 284028-89-3, MFCD16879017, 2 mg
Formula: C14H11F3N2OS, MW: 312.31, White powder, Names: 2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol.
Enzo Life Sciences GM-6001, (1mg), CAS Number: 142880-36-2
MMP inhibitor. Potent broad-spectrum hydroxamate inhibitor of matrix metalloproteinases (MMPs). .in vivo. Alternative Name: Galardin, Ilomastat, N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide. Formula: C20H28N404. MW: 388.5. CAS Number: 142880-36-2. Purity: ≥98% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO (at least 25mM) or 100% ethanol (10mg/ml). Long Term Storage: -20°C
Sigma Organic Chemistry 4-Quinolinol | 1G | 611-36-9 | MFCD00006777
4-Quinolinol, 1G
About This Item:
Storage: room temp
EINECS Number: 210-268-2