Custom Peptides
Cayman Chemical CMP-SIalIc AcIdodIum salt 10mg
A form of the sugar Neu5Ac O-linked with the nucleotide CMP; serves as the substrate for sialyltransferases, which transfer Neu5Ac from CMP-sialic acid to various acceptor substrates, most commonly at terminal positions of the oligosaccharide component of glycoproteins or glycolipids
Cayman Chemical ChlorothIazIde 10mg
An analytical reference standard categorized as a thiazide diuretic; intended for analytical forensic applications
Cayman Chemical KaempfRol 3nohSpRIdosID 10mg
A flavonoid with antioxidant and antidiabetic activities; scavenges DPPH radicals (IC50 = 79.6 UG/ml); increases glucose uptake in isolated rat soleus muscle at 1 and 100 nM; increases glycogen synthesis in isolated rat soleus muscle at 1 µM; reduces serum glucose levels in a rat model of alloxan-induced diabetes at 100 mg/kg
Cayman Chemical CGP 55845hydrochlorIde 10mg
A GABAB receptor antagonist (Ki = 4.5 nM); increases electrical stimulation-induced GABA release in the absence and presence of (–)-baclofen, as well as glutamate release in the presence of (–)-baclofen, in rat cerebral cortex slices (EC50s = 8.3, 25, and 14 nM, respectively); inhibits (–)-baclofen-induced postsynaptic hyperpolarization of evoked IPSPs and fEPSPs in rat CA1 hippocampal slices at 1 µM; increases swimming time, but does not decrease immobility time, in the forced swim test in rats at 3 or 10 mg/kg; reverses age-induced impairments in olfactory discrimination learning in rats at 0.01 and 0.1 mg/kg; increases seizure intensity in a mouse model of PTZ kindling-induced epilepsy
Cayman Chemical 5CLOro HydroCLOrothIazID 10mg
A derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms
Cayman Chemical DIhydrodaIdzeIn 10mg
An active, estrogenic metabolite of daidzein; has vasodilatory action on rat isolated aortic rings at 1 UG/ml; stimulates the estrogen receptor-dependent growth of breast cancer MCF-7 cells at micromolar concentrations
Cayman Chemical PentaNacetylchItopentaose 10mg
A pentameric chito-oligosaccharide involved in root nodulation; produced by NodC, a chito-oligosaccharide synthase, and serves as a substrate for NodL, an O-acetyltransferase; binds plant root lectins, an interaction that may be important in the promotion of cell division in the root cortex
Cayman Chemical BetaxololhydrochlorIde 10mg
A β1-AR antagonist (Ki = 23 nM); selective for the β1-AR over the β2-AR (Ki = 790 nM); cytotoxic to 10.014 pRSV-T human corneal epithelial cells; reduces intraocular pressure in cynomolgus monkeys with ocular hypertension induced by laser trabeculoplasty at 150 UG/animal; inhibits veratridine-induced sodium influx in rat cortical synaptosomes (IC50 = 28.3 µM)
Cayman Chemical 7-APDBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical MetIprnolol 10mg
A β-AR antagonist; binds to primary rabbit iris and ciliary body homogenates (Ki = 34 nM); inhibits isoproterenol-induced relaxation in guinea pig atrium and fenoterol-induced relaxation in rat uterus (pA2s = 8.3 and 8.4, respectively); inhibits anoxia-induced cell death in primary rat retinal cells and sodium nitroprusside-induced lipid peroxidation in rat primary retinal homogenates (100 μM); decreases α-chymotrypsin-induced increases in IOP in rabbits when administered topically to the eye at a dose of 0.3%; inhibits the blinking response to ocular tactile stimulation in rabbits when administered topically to the eye at a dose of 0.6%
Cayman Chemical BLP3trIfluoroacetAT salt 10mg
An antibacterial peptide; active against N. meningitidis, N. gonorrhoeae, N. lactamica, and N. cinerea at 20 UG/ml; folds into an alpha-helix, which inserts into and disrupts bacteriomimetic membranes